메뉴 건너뛰기




Volumn 8, Issue 13, 2009, Pages 2070-2079

Stat1 is an inhibitor of Ras-MAPK signaling and Rho small GTPase expression with implications in the transcriptional signature of Ras transformed cells

Author keywords

Gene expression; MAPK signaling; Protein phosphorylation; Ras transformation; Rho GTPsases; Stat proteins

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CDC42; RAC1 PROTEIN; RAS PROTEIN; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN;

EID: 67650538799     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.13.8891     Document Type: Article
Times cited : (17)

References (104)
  • 1
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002; 3:651-662
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 2
    • 1042302005 scopus 로고    scopus 로고
    • The stats of cancer - New molecular targets come of age
    • Yu H, Jove R. The stats of cancer-new molecular targets come of age. Nat Rev Cancer 2004; 4:97-105. (Pubitemid 38198738)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 5
    • 0030788405 scopus 로고    scopus 로고
    • Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
    • Chin YE, Kitagawa M, Kuida K, Flavell RA, Fu XY. Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol 1997; 17:5328-5337 (Pubitemid 27357631)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.9 , pp. 5328-5337
    • Chin, Y.E.1    Kitagawa, M.2    Kuida, K.3    Flavell, R.A.4    Fu, X.-Y.5
  • 6
    • 0029923780 scopus 로고    scopus 로고
    • Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21(WAF1/CIP1) mediated by STAT1
    • Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 1996; 272:719-722 (Pubitemid 26152783)
    • (1996) Science , vol.272 , Issue.5262 , pp. 719-722
    • Chin, Y.-E.1    Kitagawa, M.2    Su, W.-C.S.3    You, Z.-H.4    Iwamoto, Y.5    Fu, X.-Y.6
  • 7
    • 0030659512 scopus 로고    scopus 로고
    • Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
    • DOI 10.1126/science.278.5343.1630
    • Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNFalpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 1997; 278:1630-1632 (Pubitemid 27516283)
    • (1997) Science , vol.278 , Issue.5343 , pp. 1630-1632
    • Kumar, A.1    Commane, M.2    Flickinger, T.W.3    Horvath, C.M.4    Stark, G.R.5
  • 15
    • 0034658690 scopus 로고    scopus 로고
    • Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice
    • Levy DE, Gilliland DG. Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice. Oncogene 2000; 19:2505-2510 (Pubitemid 30339206)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2505-2510
    • Levy, D.E.1    Gilliland, D.G.2
  • 16
    • 45849116295 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5A/B in prostate and breast cancers
    • DOI 10.1677/ERC-08-0013
    • Tan SH, Nevalainen MT. Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Endocr Relat Cancer 2008; 15:367-390 (Pubitemid 351880829)
    • (2008) Endocrine-Related Cancer , vol.15 , Issue.2 , pp. 367-390
    • Tan, S.-H.1    Nevalainen, M.T.2
  • 17
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002; 109:1139-1142
    • (2002) J Clin Invest , vol.109 , pp. 1139-1142
    • Bromberg, J.1
  • 18
    • 58149374051 scopus 로고    scopus 로고
    • Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1
    • Wang S, Raven JF, Durbin JE, Koromilas AE. Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1. PLoS ONE 2008; 3:3476.
    • (2008) PLoS ONE , vol.3 , pp. 3476
    • Wang, S.1    Raven, J.F.2    Durbin, J.E.3    Koromilas, A.E.4
  • 19
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • DOI 10.1126/science.1072682
    • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK JNK, and p38 protein kinases. Science 2002; 298:1911-1912 (Pubitemid 35425238)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 20
    • 0031055415 scopus 로고    scopus 로고
    • Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras
    • de Rooij J, Bos JL. Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene 1997; 14:623-625 (Pubitemid 27090966)
    • (1997) Oncogene , vol.14 , Issue.5 , pp. 623-625
    • De Rooij, J.1    Bos, J.L.2
  • 21
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 23
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA and mitogen-activated protein kinases is required for Ras transformation
    • Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA and mitogen-activated protein kinases is required for Ras transformation. Mol Cell Biol 1995; 15:6443-6453
    • (1995) Mol Cell Biol , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 26
    • 0034613161 scopus 로고    scopus 로고
    • Regulation of STAT3 by direct binding to the Rac1 GTPase
    • DOI 10.1126/science.290.5489.144
    • Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL. Regulation of STAT3 by direct binding to the Rac1 GTPase. Science 2000; 290:144-147 (Pubitemid 30752089)
    • (2000) Science , vol.290 , Issue.5489 , pp. 144-147
    • Simon, A.R.1    Vikis, H.G.2    Stewart, S.3    Fanburg, B.L.4    Cochran, B.H.5    Guan, K.-L.6
  • 27
    • 0035168740 scopus 로고    scopus 로고
    • Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in RhoA GTPase oncogenic transformation
    • Aznar S, Valeron PF, del Rincon SV, Perez LF, Perona R, Lacal JC. Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation. Mol Biol Cell 2001; 12:3282-3294 (Pubitemid 33062979)
    • (2001) Molecular Biology of the Cell , vol.12 , Issue.10 , pp. 3282-3294
    • Aznar, S.1    Valeron, P.F.2    Del Rincon, S.V.3    Perez, L.F.4    Perona, R.5    Lacal, J.C.6
  • 29
    • 0037243197 scopus 로고    scopus 로고
    • STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA
    • DOI 10.1091/mbc.E02-08-0454
    • Benitah SA, Valeron PF, Rui H, Lacal JC. STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA. Mol Biol Cell 2003; 14:40-53. (Pubitemid 36106018)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.1 , pp. 40-53
    • Benitah, S.A.1    Valeron, P.F.2    Rui, H.3    Lacal, J.C.4
  • 30
    • 0036902921 scopus 로고    scopus 로고
    • Biological role of alpha-fetoprotein in cancer: Prospects for anticancer therapy
    • Mizejewski GJ. Biological role of alpha-fetoprotein in cancer: prospects for anticancer therapy. Expert Rev Anticancer Ther 2002; 2:709-735 (Pubitemid 35469493)
    • (2002) Expert Review of Anticancer Therapy , vol.2 , Issue.6 , pp. 709-735
    • Mizejewski, G.J.1
  • 33
    • 0033030593 scopus 로고    scopus 로고
    • Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer
    • DOI 10.1002/(SICI)1096-9896(199904)187:5<530::AID-PATH293>3.0.CO;2- C
    • Braungart E, Schumacher C, Hartmann E, Nekarda H, Becker KF, Hofler H, et al. Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer. J Pathol 1999; 187:530-534 (Pubitemid 29151993)
    • (1999) Journal of Pathology , vol.187 , Issue.5 , pp. 530-534
    • Braungart, E.1    Schumacher, C.2    Hartmann, E.3    Nekarda, H.4    Becker, K.-F.5    Hofler, H.6    Atkinson, M.J.7
  • 34
    • 0035952679 scopus 로고    scopus 로고
    • Autocrine and paracrine signaling through neuropeptide receptors in human cancer
    • DOI 10.1038/sj.onc.1204183
    • Heasley LE. Autocrine and paracrine signaling through neuropeptide receptors in human cancer. Oncogene 2001; 20:1563-1569 (Pubitemid 32336844)
    • (2001) Oncogene , vol.20 , Issue.13 REV. ISS. 1 , pp. 1563-1569
    • Heasley, L.E.1
  • 36
    • 0033233233 scopus 로고    scopus 로고
    • INK4b gene methylation and myelodysplastic syndromes
    • INK4b gene methylation and myelodysplastic syndromes. Leuk Lymphoma 1999; 35:437-443
    • (1999) Leuk Lymphoma , vol.35 , pp. 437-443
    • Quesnel, B.1    Fenaux, P.2
  • 37
    • 0030299866 scopus 로고    scopus 로고
    • INK4 genes in hematologic malignancies
    • INK4 genes in hematologic malignancies. Leuk Lymphoma 1996; 23:235-245
    • (1996) Leuk Lymphoma , vol.23 , pp. 235-245
    • Heyman, M.1    Einhorn, S.2
  • 38
    • 0037667420 scopus 로고    scopus 로고
    • Targeting HER1/EGFR: A molecular approach to cancer therapy
    • Arteaga C. Targeting HER1/EGFR: a molecular approach to cancer therapy. Semin Oncol 2003; 30:3-14. (Pubitemid 36828623)
    • (2003) Seminars in Oncology , vol.30 , Issue.3 SUPPL. 7 , pp. 3-14
    • Arteaga, C.L.1
  • 42
    • 0037086294 scopus 로고    scopus 로고
    • The MAGE proteins: Emerging roles in cell cycle progression, apoptosis, and neurogenetic disease
    • DOI 10.1002/jnr.10160
    • Barker PA, Salehi A. The MAGE proteins: emerging roles in cell cycle progression, apoptosis and neurogenetic disease. J Neurosci Res 2002; 67:705-712 (Pubitemid 34226281)
    • (2002) Journal of Neuroscience Research , vol.67 , Issue.6 , pp. 705-712
    • Barker, P.A.1    Salehi, A.2
  • 43
    • 0036730427 scopus 로고    scopus 로고
    • The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
    • DOI 10.1038/ng959
    • Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 2002; 32:128-134 (Pubitemid 34977207)
    • (2002) Nature Genetics , vol.32 , Issue.1 , pp. 128-134
    • Kawaguchi, Y.1    Cooper, B.2    Gannon, M.3    Ray, M.4    MacDonald, R.J.5    Wright, C.V.E.6
  • 44
    • 0842265835 scopus 로고    scopus 로고
    • Midkine and pleiotrophin in neural development and cancer
    • DOI 10.1016/S0304-3835(03)00450-6
    • Kadomatsu K, Muramatsu T. Midkine and pleiotrophin in neural development and cancer. Cancer Lett 2004; 204:127-143 (Pubitemid 38167717)
    • (2004) Cancer Letters , vol.204 , Issue.2 , pp. 127-143
    • Kadomatsu, K.1    Muramatsu, T.2
  • 46
    • 1842535903 scopus 로고    scopus 로고
    • Shutting down Wnt signal-activated cancer
    • DOI 10.1038/ng0404-320
    • Taketo MM. Shutting down Wnt signal-activated cancer. Nat Genet 2004; 36:320-322 (Pubitemid 38437248)
    • (2004) Nature Genetics , vol.36 , Issue.4 , pp. 320-322
    • Taketo, M.M.1
  • 48
    • 0038236713 scopus 로고    scopus 로고
    • Tenascins: Regulation and putative functions during pathological stress
    • DOI 10.1002/path.1415
    • Chiquet-Ehrismann R, Chiquet M. Tenascins: regulation and putative functions during pathological stress. J Pathol 2003; 200:488-499 (Pubitemid 36818249)
    • (2003) Journal of Pathology , vol.200 , Issue.4 , pp. 488-499
    • Chiquet-Ehrismann, R.1    Chiquet, M.2
  • 49
    • 4444353257 scopus 로고    scopus 로고
    • Tumor progression: The effects of thrombospondin-1 and -2
    • Lawler J, Detmar M. Tumor progression: the effects of thrombospondin-1 and -2. Int J Biochem Cell Biol 2004; 36:1038-1045
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1038-1045
    • Lawler, J.1    Detmar, M.2
  • 50
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGFbeta in homeostasis and cancer
    • Siegel PM, Massague J. Cytostatic and apoptotic actions of TGFbeta in homeostasis and cancer. Nat Rev Cancer 2003; 3:807-821 (Pubitemid 37376979)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.11 , pp. 807-820
    • Siegel, P.M.1    Massague, J.2
  • 52
    • 0038175548 scopus 로고    scopus 로고
    • Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation
    • DOI 10.1074/jbc.M210945200
    • Soon LL, Yie TA, Shvarts A, Levine AJ, Su F, Tchou-Wong KM. Overexpression of WISP-1 downregulated motility and invasion of lung cancer cells through inhibition of Rac activation. J Biol Chem 2003; 278:11465-11470 (Pubitemid 36792706)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.13 , pp. 11465-11470
    • Soon, L.L.1    Yie, T.-A.2    Shvarts, A.3    Levine, A.J.4    Su, F.5    Tchou-Wong, K.-M.6
  • 54
    • 0026774234 scopus 로고
    • Cellular retinol-binding protein functions in the regulation of retinoid metabolism
    • Wolf G. Cellular retinol-binding protein functions in the regulation of retinoid metabolism. Nutr Rev 1992; 50:197-199
    • (1992) Nutr Rev , vol.50 , pp. 197-199
    • Wolf, G.1
  • 55
    • 1842865304 scopus 로고    scopus 로고
    • Development of human lymphohematopoiesis defined by CD34 and CD81 expression
    • DOI 10.1080/1042819021000039974
    • Tsuji K, Feng MA, Wang D. Development of human lymphohematopoiesis defined by CD34 and CD81 expression. Leuk Lymphoma 2002; 43:2269-2273 (Pubitemid 35386149)
    • (2002) Leukemia and Lymphoma , vol.43 , Issue.12 , pp. 2269-2273
    • Tsuji, K.1    Ma, F.2    Wang, D.3
  • 56
    • 0034738420 scopus 로고    scopus 로고
    • p21(WAF1/Cip1): More than a break to the cell cycle?
    • Dotto GP. p21(WAF1/Cip1): more than a break to the cell cycle? Biochim Biophys Acta 2000; 1471:43-56.
    • (2000) Biochim Biophys Acta , vol.1471 , pp. 43-56
    • Dotto, G.P.1
  • 57
    • 0033574432 scopus 로고    scopus 로고
    • Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53+/+ cells
    • Reimer CL, Borras AM, Kurdistani SK, Garreau JR, Chung M, Aaronson SA, et al. Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53+/+ cells. J Biol Chem 1999; 274:11022-11029 (Pubitemid 129528309)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.16 , pp. 11022-11029
    • Reimer, C.L.1    Borras, A.M.2    Kurdistani, S.K.3    Garreau, J.R.4    Chung, M.5    Aaronson, S.A.6    Lee, S.W.7
  • 58
    • 0036101808 scopus 로고    scopus 로고
    • A regulator of the p53-Mdm2 network
    • Chen X. Cyclin G: a regulator of the p53-Mdm2 network. Dev Cell 2002; 2:518-519
    • (2002) Dev Cell , vol.2 , pp. 518-519
    • Chen, X.1    Cyclin, G.2
  • 59
    • 0035860820 scopus 로고    scopus 로고
    • Kruppel-like Factors: Three Fingers in Many Pies
    • DOI 10.1074/jbc.R100043200
    • Bieker JJ. Kruppel-like factors: three fingers in many pies. J Biol Chem 2001; 276:34355-34358 (Pubitemid 37384419)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.37 , pp. 34355-34358
    • Bieker, J.J.1
  • 60
    • 0842329848 scopus 로고    scopus 로고
    • Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • DOI 10.1038/sj.onc.1207067
    • Zhao W, Hisamuddin IM, Nandan MO, Babbin BA, Lamb NE, Yang VW. Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 2004; 23:395-402. (Pubitemid 38174993)
    • (2004) Oncogene , vol.23 , Issue.2 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3    Babbin, B.A.4    Lamb, N.E.5    Yang, V.W.6
  • 61
    • 0032899625 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-6: The "forgotten" binding protein?
    • Bach LA. Insulin-like growth factor binding protein-6: the "forgotten" binding protein? Horm Metab Res 1999; 31:226-234
    • (1999) Horm Metab Res , vol.31 , pp. 226-234
    • Bach, L.A.1
  • 63
    • 1542269303 scopus 로고    scopus 로고
    • Integrins: Roles in cancer development and as treatment targets
    • DOI 10.1038/sj.bjc.6601576
    • Jin H, Varner J. Integrins: roles in cancer development and as treatment targets. Br J Cancer 2004; 90:561-565 (Pubitemid 38297190)
    • (2004) British Journal of Cancer , vol.90 , Issue.3 , pp. 561-565
    • Jin, H.1    Varner, J.2
  • 64
    • 0035479918 scopus 로고    scopus 로고
    • The alpha6beta4 integrin and epithelial cell migration
    • DOI 10.1016/S0955-0674(00)00249-0
    • Mercurio AM, Rabinovitz I, Shaw LM. The alpha6beta4 integrin and epithelial cell migration. Curr Opin Cell Biol 2001; 13:541-545 (Pubitemid 32817011)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.5 , pp. 541-545
    • Mercurio, A.M.1    Rabinovitz, I.2    Shaw, L.M.3
  • 65
    • 0037216328 scopus 로고    scopus 로고
    • Induction of p202, a modulator of apoptosis, during oncogenic transformation of NIH 3T3 cells by activated H-ras (Q61 L) contributes to cell survival
    • DOI 10.1002/jcb.10372
    • Xin H, Geng Y, Pramanik R, Choubey D. Induction of p202, a modulator of apoptosis, during oncogenic transformation of NIH 3T3 cells by activated H-Ras (Q61L) contributes to cell survival. J Cell Biochem 2003; 88:191-204. (Pubitemid 36015088)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.1 , pp. 191-204
    • Xin, H.1    Geng, Y.2    Pramanik, R.3    Choubey, D.4
  • 66
    • 0029656068 scopus 로고    scopus 로고
    • The interferon-inducible p202 protein as a modulator of transcription: Inhibition of NF-kappaB, c-Fos, and c-Jun activities
    • Min W, Ghosh S, Lengyel P. The interferon-inducible p202 protein as a modulator of transcription: inhibition of NFkappa B, c-Fos and c-Jun activities. Mol Cell Biol 1996; 16:359-368 (Pubitemid 126506982)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.1 , pp. 359-368
    • Min, W.1    Ghosh, S.2    Lengyel, P.3
  • 69
    • 0038069515 scopus 로고    scopus 로고
    • MHC class I antigens, immune surveillance, and tumor immune escape
    • DOI 10.1002/jcp.10290
    • Garcia-Lora A, Algarra I, Garrido F. MHC class I antigens, immune surveillance and tumor immune escape. J Cell Physiol 2003; 195:346-355 (Pubitemid 36529863)
    • (2003) Journal of Cellular Physiology , vol.195 , Issue.3 , pp. 346-355
    • Garcia-Lora, A.1    Algarra, I.2    Garrido, F.3
  • 70
    • 3042841001 scopus 로고    scopus 로고
    • Characterization of human mesothelin transcripts in ovarian and pancreatic cancer
    • DOI 10.1186/1471-2407-4-19
    • Muminova ZE, Strong TV, Shaw DR. Characterization of human mesothelin transcripts in ovarian and pancreatic cancer. BMC Cancer 2004; 4:19. (Pubitemid 38851354)
    • (2004) BMC Cancer , vol.4 , pp. 19
    • Muminova, Z.E.1    Strong, T.V.2    Shaw, D.R.3
  • 72
    • 1542395668 scopus 로고    scopus 로고
    • Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors
    • DOI 10.1016/j.gene.2003.12.002, PII S0378111903011314
    • Bowers AJ, Boylan JF. Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Gene 2004; 328:135-142 (Pubitemid 38352890)
    • (2004) Gene , vol.328 , Issue.1-2 , pp. 135-142
    • Bowers, A.J.1    Boylan, J.F.2
  • 73
    • 0032692783 scopus 로고    scopus 로고
    • Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus and agenesis of the corpus callosum
    • das Neves L, Duchala CS, Tolentino-Silva F, Haxhiu MA, Colmenares C, Macklin WB, et al. Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus and agenesis of the corpus callosum. Proc Natl Acad Sci USA 1999; 96:11946-11951
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11946-11951
    • Das Neves, L.1    Duchala, C.S.2    Tolentino-Silva, F.3    Haxhiu, M.A.4    Colmenares, C.5    Macklin, W.B.6
  • 74
    • 0037047430 scopus 로고    scopus 로고
    • Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta- mediated nuclear protein import
    • DOI 10.1016/S0092-8674(02)00836-X
    • Lindsay ME, Plafker K, Smith AE, Clurman BE, Macara IG. Npap60/Nup50 is a tristable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell 2002; 110:349-360 (Pubitemid 34899383)
    • (2002) Cell , vol.110 , Issue.3 , pp. 349-360
    • Lindsay, M.E.1    Plafker, K.2    Smith, A.E.3    Clurman, B.E.4    Macara, I.G.5
  • 75
    • 0034673929 scopus 로고    scopus 로고
    • Groucho/TLE family proteins and transcriptional repression
    • DOI 10.1016/S0378-1119(00)00161-X, PII S037811190000161X
    • Chen G, Courey AJ. Groucho/TLE family proteins and transcriptional repression. Gene 2000; 249:1-16. (Pubitemid 30265483)
    • (2000) Gene , vol.249 , Issue.1-2 , pp. 1-16
    • Chen, G.1    Courey, A.J.2
  • 76
    • 0033093561 scopus 로고    scopus 로고
    • Is CD81 the key to hepatitis C virus entry?
    • Rice CM. Is CD81 the key to hepatitis C virus entry? Hepatology 1999; 29:990-992
    • (1999) Hepatology , vol.29 , pp. 990-992
    • Rice, C.M.1
  • 77
    • 0031895778 scopus 로고    scopus 로고
    • CD81 (TAPA-1): A molecule involved in signal transduction and cell adhesion in the immune system
    • DOI 10.1146/annurev.immunol.16.1.89
    • Levy S, Todd SC, Maecker HT. CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu Rev Immunol 1998; 16:89-109. (Pubitemid 28183360)
    • (1998) Annual Review of Immunology , vol.16 , pp. 89-109
    • Levy, S.1    Todd, S.C.2    Maecker, H.T.3
  • 78
    • 0347133261 scopus 로고    scopus 로고
    • The Role of CSF-1 in Normal Physiology of Mammary Gland and Breast Cancer: An Update
    • Sapi E. The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood) 2004; 229:1-11. (Pubitemid 38101673)
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.1 , pp. 1-11
    • Sapi, E.1
  • 81
    • 0036337388 scopus 로고    scopus 로고
    • Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins
    • DOI 10.1128/MCB.22.17.6100-6110.2002
    • Brott BK, Sokol SY. Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol Cell Biol 2002; 22:6100-6110 (Pubitemid 34857830)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.17 , pp. 6100-6110
    • Brott, B.K.1    Sokol, S.Y.2
  • 82
    • 0034649592 scopus 로고    scopus 로고
    • Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling
    • DOI 10.1016/S0960-9822(00)00868-X
    • Wu W, Glinka A, Delius H, Niehrs C. Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling. Curr Biol 2000; 10:1611-1614 (Pubitemid 32062666)
    • (2000) Current Biology , vol.10 , Issue.24 , pp. 1611-1614
    • Wu, W.1    Glinka, A.2    Delius, H.3    Niehrs, C.4
  • 86
    • 0034077278 scopus 로고    scopus 로고
    • Increased expression of heparin binding EGF (HB-EGF), amphiregulin, TGFalpha and epiregulin in androgen-independent prostate cancer cell lines
    • Torring N, Jorgensen PE, Sorensen BS, Nexo E. Increased expression of heparin binding EGF (HB-EGF), amphiregulin, TGFalpha and epiregulin in androgen-independent prostate cancer cell lines. Anticancer Res 2000; 20:91-95
    • (2000) Anticancer Res , vol.20 , pp. 91-95
    • Torring, N.1    Jorgensen, P.E.2    Sorensen, B.S.3    Nexo, E.4
  • 87
    • 0042855006 scopus 로고    scopus 로고
    • IGF-binding protein-4: Biochemical characteristics and functional consequences
    • DOI 10.1677/joe.0.1780177
    • Zhou R, Diehl D, Hoeflich A, Lahm H, Wolf E. IGF-binding protein-4: biochemical characteristics and functional consequences. J Endocrinol 2003; 178:177-193 (Pubitemid 37063060)
    • (2003) Journal of Endocrinology , vol.178 , Issue.2 , pp. 177-193
    • Zhou, R.1    Diehl, D.2    Hoeflich, A.3    Lahm, H.4    Wolf, E.5
  • 90
    • 0034566515 scopus 로고    scopus 로고
    • Regulation of interleukin-6 secretion from breast cancer cells and its clinical implications
    • Kurebayashi J. Regulation of interleukin-6 secretion from breast cancer cells and its clinical implications. Breast Cancer 2000; 7:124-129
    • (2000) Breast Cancer , vol.7 , pp. 124-129
    • Kurebayashi, J.1
  • 91
    • 0141721621 scopus 로고    scopus 로고
    • Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: Novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders
    • Autiero M, Luttun A, Tjwa M, Carmeliet P. Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders. J Thromb Haemost 2003; 1:1356-1370
    • (2003) J Thromb Haemost , vol.1 , pp. 1356-1370
    • Autiero, M.1    Luttun, A.2    Tjwa, M.3    Carmeliet, P.4
  • 92
    • 0037380709 scopus 로고    scopus 로고
    • Novel PDGF family members: PDGF-C and PDGF-D
    • DOI 10.1016/S1359-6101(02)00090-4
    • Li X, Eriksson U. Novel PDGF family members: PDGF-C and PDGF-D. Cytokine Growth Factor Rev 2003; 14:91-98 (Pubitemid 36389523)
    • (2003) Cytokine and Growth Factor Reviews , vol.14 , Issue.2 , pp. 91-98
    • Li, X.1    Eriksson, U.2
  • 93
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • DOI 10.1038/nrc1075
    • Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003; 3:362-374 (Pubitemid 37328856)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 94
    • 4444221676 scopus 로고    scopus 로고
    • From structure to disease: The evolving tale of aquaporin biology
    • DOI 10.1038/nrm1469
    • King LS, Kozono D, Agre P. From structure to disease: the evolving tale of aquaporin biology. Nat Rev Mol Cell Biol 2004; 5:687-698 (Pubitemid 39208179)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.9 , pp. 687-698
    • King, L.S.1    Kozono, D.2    Agre, P.3
  • 95
    • 0033541389 scopus 로고    scopus 로고
    • The CCN family of angiogenic regulators: The integrin connection
    • DOI 10.1006/excr.1999.4456
    • Lau LF, Lam SC. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 1999; 248:44-57. (Pubitemid 29393928)
    • (1999) Experimental Cell Research , vol.248 , Issue.1 , pp. 44-57
    • Lau, L.F.1    Lam, S.C.-T.2
  • 99
    • 33645839013 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs
    • Klampfer L. Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs. Curr Cancer Drug Targets 2006; 6:107-121
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 107-121
    • Klampfer, L.1
  • 101
    • 0035958080 scopus 로고    scopus 로고
    • Enhanced Antiviral and Antiproliferative Properties of a STAT1 Mutant Unable to Interact with the Protein Kinase PKR
    • Wong AH, Durbin JE, Li S, Dever TE, Decker T, Koromilas AE. Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR. J Biol Chem 2001; 276:13727-13737 (Pubitemid 37391746)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.17 , pp. 13727-13737
    • Wong, A.H.-T.1    Durbin, J.E.2    Li, S.3    Dever, T.E.4    Decker, T.5    Koromilas, A.E.6
  • 102
  • 103
    • 0038660670 scopus 로고    scopus 로고
    • RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation
    • DOI 10.1074/jbc.M212776200
    • Sauzeau V, Rolli-Derkinderen M, Marionneau C, Loirand G, Pacaud P. RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation. J Biol Chem 2003; 278:9472-9480 (Pubitemid 36800439)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.11 , pp. 9472-9480
    • Sauzeau, V.1    Rolli-Derkinderen, M.2    Marionneau, C.3    Loirand, G.4    Pacaud, P.5
  • 104
    • 0035699287 scopus 로고    scopus 로고
    • Characterization of variability in large-scale gene expression data: Implications for study design
    • Novak JP, Sladek R, Hudson TJ. Characterization of variability in large-scale gene expression data: implications for study design. Genomics 2002; 79:104-113
    • (2002) Genomics , vol.79 , pp. 104-113
    • Novak, J.P.1    Sladek, R.2    Hudson, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.