Evidence for a second, high affinity Gβγ binding site on Gαi1 (GDP) subunits

Journal of Biological Chemistry

Volumn 284, Issue 25, 2009, Pages 16906-16913

  Wang, Jingting ^a   Sengupta, Parijat ^a   Guo, Yuanjian ^a   Golebiewska, Ursula ^b   Scarlata, Suzanne ^c  

^a STONY BROOK UNIVERSITY   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

^c QUEENSBOROUGH COMMUNITY COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR PROTEINS; CONFORMATIONAL CHANGE; CULTURED CELL; G PROTEIN; HETEROTRIMER; HIGH AFFINITY; IN-CELL; MOLECULAR DOCKING; PHOSPHOLIPASE C; SYNTHETIC PEPTIDE;

AMINES; BINDING ENERGY; PROTEINS;

BINDING SITES;

CYAN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; PHOSPHOLIPASE C BETA2; YELLOW FLUORESCENT PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; BIOPHYSICS; CELL CULTURE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE;

BINDING SITES; CELL LINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; KINETICS; LUMINESCENT PROTEINS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS;

EID: 67650532176     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.006585     Document Type: Article

References (44)

1. Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., and Watson, J. (1994) Molecular Biology of the Cell, pp. 734-758, Garland, New York
2. Edidin, M. (2003) Annu. Rev. Biophys. Biomol. Struct. 32, 257-283
3. Anderson, R. G. (1998) Annu. Rev. Biochem. 67, 199-225
4. Bünemann, M., Frank, M., and Lohse, M. J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 16077-16082
5. Nobles, M., Benians, A., and Tinker, A. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 18706-18711
6. Dowal, L., Provitera, P., and Scarlata, S. (2006) J. Biol. Chem. 281, 23999-24014
7. Philip, F., Sengupta, P., and Scarlata, S. (2007) J. Biol. Chem. 282, 19203-19216
8. Golebiewska, U., and Scarlata, S. (2008) Biophys. J. 95, 2575-2582
9. Neer, E. J. (1995) Cell 80, 249-257
10. Neer, E. J. (1994) Protein Science 3, 3-14
11. Birnbaumer, L. (2007) Biochim. Biophys. Acta 1768, 772-793
12. Exton, J. H. (1997) Eur. J. Biochem. 243, 10-20
13. Runnels, L. W., and Scarlata, S. F. (1999) Biochemistry 38, 1488-1496
14. Janetopoulos, C., Jin, T., and Devreotes, P. (2001) Science 291, 2408-2411
15. Hughes, T. E., Zhang, H., Logothetis, D. E., and Berlot, C. H. (2001) J. Biol. Chem. 276, 4227-4235
16. Hynes, T. R., Mervine, S. M., Yost, E. A., Sabo, J. L., and Berlot, C. H. (2004) J. Biol. Chem. 279, 44101-44112
17. Digby, G. J., Lober, R. M., Sethi, P. R., and Lambert, N. A. (2006) Proc. Nat. Acad. Sci. U. S. A. 103, 17789-17794
18. Hildebrandt, J. D. (1997) Biochem. Pharmacol. 54, 325-339
19. Sarvazyan, N. A., Lim, W. K., and Neubig, R. R. (2002) Biochemistry 41, 12858-12867
20. Wedegaertner, P. B., Wilson, P. T., and Bourne, H. R. (1995) J. Biol. Chem. 270, 503-506
21. Tesmer, J. J., Berman, D. M., Gilman, A. G., and Sprang, S. R. (1997) Cell 89, 251-261
22. Tesmer, J. J., Sunahara, R. K., Gilman, A. G., and Sprang, S. R. (1997) Science 278, 1907-1916
23. Rebecchi, M. J., and Pentyala, S. N. (2000) Physiol. Rev. 80, 1291-1335
24. Wang, J., Golebiewska, U., and Scarlata, S. (2009) J. Molec. Biol. 387, 92-103
25. Medkova, M., Preininger, A. M., Yu, N. J., Hubbell, W. L., and Hamm, H. E. (2002) Biochemistry 41, 9962-9972
26. Skiba, N. P., Bae, H., and Hamm, H. E. (1996) J. Biol. Chem. 271, 413-424
27. Chidiac, P., Markin, V. S., and Ross, E. M. (1999) Biochem. Pharm. 58, 39-48
28. Runnels, L. W., and Scarlata, S. F. (1998) Biochemistry 37, 15563-15574
29. Chen, Y., Müller, J. D., So, P. T. C., and Gratton, E. (1999) Biophys. J. 77, 553-567
30. van der Meer, W., Coker G., and Chen, S. S. Y. (1994) Resonance Energy Transfer, Theory and Data, pp. 148-164, VCH Publishers, Inc., New York
31. Wall, M. A., Coleman, D. E., Lee, E., Iñiguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., and Sprang, S. R. (1995) Cell 83, 1047-1058
32. Schwille, P. (2001) Cell. Biochem. Biophys. 34, 383-408
33. Exton, J. H. (1994) Annu. Rev. physiol. 56, 349-369
34. Suh, P. G., Park, J. I., Manzoli, L., Cocco, L., Peak, J. C., Katan, M., Fukami, K., Kataoka, T., Yun, S., and Ryu, S. H. (2008) BMB reports 41, 415-434
35. Li, Y., Sternweis, P. M., Charnecki, S., Smith, T. F., Gilman, A. G., Neer, E. J., and Kozasa, T. (1998) J. Biol. Chem. 273, 16265-16272
36. Panchenko, M. P., Saxena, K., Li, Y., Charnecki, S., Sternweis, P. M., Smith, T. F., Gilman, A. G., Kozasa, T., and Neer, E. J. (1998) J. Biol. Chem. 273, 28298-28304
37. Buck, E., Li, J., Chen, Y., Weng, G., Scarlata, S., and Iyengar, R. (1999) Science 283, 1332-1335
38. Murray, D., McLaughlin, S., and Honig, B. (2001) J. Biol. Chem. 276, 45153-45159
39. Drin, G., and Scarlata, S. (2007) Cell. Signal. 19, 1383-1392
40. Drin, G., Douguet, D., and Scarlata, S. (2006) Biochemistry 45, 5712-5724
41. Cabrera-Vera, T. M., Vanhauwe, J., Thomas, T. O., Medkova, M., Preininger, A., Mazzoni, M. R., and Hamm, H. E. (2003) Endocr. Rev. 24, 765-781
42. Lodowski, D. T., Pitcher, J. A., Capel, W. D., Lefkowitz, R. J., and Tesmer, J. J. (2003) Science 300, 1256-1262
43. Diel, S., Klass, K., Wittig, B., and Kleuss, C. (2006) J. Biol. Chem. 281, 288-294
44. Buck, E., Schatz, P., Scarlata, S., and Iyengar, R. (2002) J. Biol. Chem. 277, 49707-49715