GSH-dependent iNOS and HO-1 mediated apoptosis of human Jurkat cells induced by nickel(II)

Environmental Toxicology

Volumn 24, Issue 4, 2009, Pages 404-414

  Zhang, Dongmei ^a   Shen, Jie ^a   Wang, Cuicui ^a   Zhang, Xin ^a   Chen, Junhui ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; HO 1; Nickel; Nitric oxide; ROS

Indexed keywords

ANTIAPOPTOTIC; APOPTOSIS; DOWN-REGULATION; ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); EXPRESSION LEVELS; GLUTATHIONE; HEME OXYGENASE-1; HO-1; HUMAN T LYMPHOCYTES; IMMUNE CELLS; IN-CELL; INDUCED APOPTOSIS; INDUCIBLE NITRIC OXIDE SYNTHASE (INOS); JURKAT CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PATHWAYS; MOLECULAR MECHANISM; MRNA LEVEL; N-ACETYLCYSTEINE; NITRATE LEVELS; PRELIMINARY DATA; REACTIVE OXYGEN SPECIES; ROS; TIME-DEPENDENT;

CELL DEATH; CELL MEMBRANES; ENDOTHELIAL CELLS; ENZYMES; LAWS AND LEGISLATION; NICKEL; NICKEL ALLOYS; NITRIC OXIDE; OXYGEN; PORPHYRINS; SULFUR COMPOUNDS; TOXICITY; TRANSITION METAL COMPOUNDS;

NICKEL OXIDE;

ACETYLCYSTEINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NICKEL; NITRATE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; CYTOLOGY; GENE EXPRESSION; HORMONE; NICKEL;

APOPTOSIS; ARTICLE; ASSAY; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOTOXICITY; INBORN ERROR OF METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ACETYLCYSTEINE; ANTIOXIDANTS; APOPTOSIS; CELLS, CULTURED; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEME OXYGENASE-1; HUMANS; JURKAT CELLS; NICKEL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTES;

EID: 67650477734     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20440     Document Type: Article

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