Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells

Chemical Research in Toxicology

Volumn 19, Issue 3, 2006, Pages 399-406

  Li, Chun Qi ^a   Pang, Bo ^a   Kiziltepe, Tanyel ^a   Trudel, Laura J ^a   Engelward, Bevin P ^a   Dedon, Peter C ^a   Wogan, Gerald N ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; HYPOXANTHINE; NITRIC OXIDE; NUCLEIC ACID BASE; PROTEIN KINASE B; PROTEIN P53; THYMIDINE KINASE; URACIL; XANTHINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL DAMAGE; CELL DEATH; CELL LINE; CELL PROTECTION; CELL STRAIN NH32; CELL STRAIN TK6; CELL TYPE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEAMINATION; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; GENE; GENE DELIVERY SYSTEM; GENE LOCUS; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MAXIMUM ALLOWABLE CONCENTRATION; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MUTAGENESIS; NULL ALLELE; SIGNAL TRANSDUCTION; STEADY STATE; TK1 GENE; TUMOR SUPPRESSOR GENE;

BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMET ASSAY; DNA DAMAGE; DNA REPAIR; HUMANS; MASS SPECTROMETRY; MEMBRANE POTENTIALS; MUTAGENESIS; NITRIC OXIDE; SISTER CHROMATID EXCHANGE; THYMIDINE KINASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33645470326     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050283e     Document Type: Article

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