Synthesis of new acridines and hydrazones derived from cyclic β-diketone for cytotoxic and antiviral evaluation

European Journal of Medicinal Chemistry

Volumn 44, Issue 9, 2009, Pages 3680-3686

  El Sabbagh, Osama I ^a   Rady, Hanaa M ^b  

^a Zagazig University   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Acridines; Antiviral activity; Cytotoxic; Hydrazones

Indexed keywords

2 (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYLAMINO) N' (4 CHLOROBENZYLIDENE)ACETOHYDRAZIDE; 2 (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYLAMINO)ACETOHYDRAZIDE; 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ACRIDINE DERIVATIVE; AMANTADINE; ETHYL 2 [9 PHENYL 1,2,3,4,5,6,7,8 OCTAHYDRO 3,3,6,6 TETRAMETHYL 1,8 DIOXOACRIDIN 10(9H) YL]ACETATE; HYDRAZIDE DERIVATIVE; HYDRAZONE DERIVATIVE; N1 [2 (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYLAMINO)ACETYL] N4 (2 CHLOROETHYL)SEMICARBAZIDE; N1 [2 (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYLAMINO)ACETYL] N4 PHENYLTHIOSEMICARBAZIDE; THIADIAZOLE DERIVATIVE; THIOSEMICARBAZIDE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS A VIRUS; HUMAN; HUMAN CELL; NONHUMAN;

ACRIDINES; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HEPATITIS A; HEPATITIS A VIRUS; HUMANS; HYDRAZONES; LIVER; MICROBIAL SENSITIVITY TESTS; SEMICARBAZIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67650429675     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.04.001     Document Type: Article

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