Synthesis of 9-acridinyl sulfur derivatives: Sulfides, sulfoxides and sulfones. Comparison of their activity on tumour cells

European Journal of Medicinal Chemistry

Volumn 39, Issue 12, 2004, Pages 1029-1038

  Santelli Rouvier, Christiane ^a   Barret, Jean Marc ^b   Farrell, Christopher M ^c   Sharples, Derek ^c   Hill, Bridget T ^b   Barbe, Jacques ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b Centre d'Immunologie Pierre Fabre   (France)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Acridine sulfides; Anticancer activity; DNA interaction; Sulfones; Sulfoxides

Indexed keywords

2,7 DIMETHOXY 9 (2' CHLOROETHYLSULFINYL)ACRIDINE; 2,7 DIMETHOXY 9 (2' CHLOROETHYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 (2' DIETHYLAMINOETHYLSULFINYL)ACRIDINE; 2,7 DIMETHOXY 9 (2' DIETHYLAMINOETHYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 (2' HYDROXYETHYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 (2',3' EPOXYPROPYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 (4' NITROBENZYLSULFINYL)ACRIDINE; 2,7 DIMETHOXY 9 (4' NITROBENZYLSULFONYL)ACRIDINE; 2,7 DIMETHOXY 9 (4' NITROBENZYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 (BENZYLSULFINYL)ACRIDINE; 2,7 DIMETHOXY 9 (ETHENOSULFONYL)ACRIDINE; 2,7 DIMETHOXY 9 (ETHYLSULFINYL)ACRIDINE; 2,7 DIMETHOXY 9 (ETHYLSULFONYL)ACRIDINE; 2,7 DIMETHOXY 9 (ETHYLTHIO)ACRIDINE; 2,7 DIMETHOXY 9 BENZYLTHIOACRIDINE; 3 CHLORO 9 (2',3' EPOXYPROPYLTHIO)ACRIDINE; 9 (2' CHLOROETHYLSULFINYL)ACRIDINE; 9 (2' CHLOROETHYLTHIO)ACRIDINE; 9 (2',3' EPOXYPROPYLTHIO)ACRIDINE; 9 (4' CHLOROBUTYLTHIO)ACRIDINE; MUSTARD GAS; SULFIDE; SULFONE; SULFOXIDE; SULFUR DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATION; SCREENING TEST; TUMOR CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES; SULFONES; SULFOXIDES;

EID: 9644273901     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.06.015     Document Type: Article

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