Purinergic P2X7 receptor antagonists: Chemistry and fundamentals of biological screening

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 14, 2009, Pages 4861-4865

  Gunosewoyo, Hendra ^a,b   Coster, Mark J ^c   Bennett, Maxwell R ^b   Kassiou, Michael ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c GRIFFITH UNIVERSITY   (Australia)

Author keywords

Cytokine release; LL 37; P2X7 antagonists; Rational drug design

Indexed keywords

A 740003; A 804598; A 824598; BENZAMIDE DERIVATIVE; GUANIDINE DERIVATIVE; HYDRAZIDE DERIVATIVE; MASSADINE; PROTOBERBERINE; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; STYLISSADINE A; STYLISSADINE B; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; SHORT SURVEY;

ANIMALS; BENZAMIDES; BINDING SITES; BIOLOGICAL PRODUCTS; DRUG EVALUATION, PRECLINICAL; GUANIDINES; HUMANS; HYDRAZINES; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, PURINERGIC P2; TRIAZOLES;

EID: 67650034171     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.083     Document Type: Short Survey

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