메뉴 건너뛰기




Volumn 94, Issue 2, 2009, Pages 94-100

Finding disease-specific coordinated functions by multi-function genes: Insight into the coordination mechanisms in diseases

Author keywords

Cancer; Disease gene; Gene functions; Gene mutation; Gene ontology; Protein protein interaction

Indexed keywords

ATM PROTEIN; PROTEIN P53; SOMATOMEDIN C RECEPTOR;

EID: 67649979842     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2009.05.001     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 13944272315 scopus 로고    scopus 로고
    • Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kappaB signaling modules
    • Kim T., Yoon J., Cho H., Lee W.B., Kim J., Song Y.H., Kim S.N., Yoon J.H., Kim-Ha J., and Kim Y.J. Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kappaB signaling modules. Nat. Immunol. 6 2 (2005) 211-218
    • (2005) Nat. Immunol. , vol.6 , Issue.2 , pp. 211-218
    • Kim, T.1    Yoon, J.2    Cho, H.3    Lee, W.B.4    Kim, J.5    Song, Y.H.6    Kim, S.N.7    Yoon, J.H.8    Kim-Ha, J.9    Kim, Y.J.10
  • 4
    • 33846928211 scopus 로고    scopus 로고
    • GO-2D: identifying 2-dimensional cellular-localized functional modules in Gene Ontology
    • Zhu J., Wang J., Guo Z., Zhang M., Yang D., Li Y., Wang D., and Xiao G. GO-2D: identifying 2-dimensional cellular-localized functional modules in Gene Ontology. BMC Genomics 8 (2007) 30
    • (2007) BMC Genomics , vol.8 , pp. 30
    • Zhu, J.1    Wang, J.2    Guo, Z.3    Zhang, M.4    Yang, D.5    Li, Y.6    Wang, D.7    Xiao, G.8
  • 6
    • 18744389489 scopus 로고    scopus 로고
    • Significance analysis of functional categories in gene expression studies: a structured permutation approach
    • Barry W.T., Nobel A.B., and Wright F.A. Significance analysis of functional categories in gene expression studies: a structured permutation approach. Bioinformatics 21 9 (2005) 1943-1949
    • (2005) Bioinformatics , vol.21 , Issue.9 , pp. 1943-1949
    • Barry, W.T.1    Nobel, A.B.2    Wright, F.A.3
  • 7
    • 41449085571 scopus 로고    scopus 로고
    • Eigengene networks for studying the relationships between co-expression modules
    • Langfelder P., and Horvath S. Eigengene networks for studying the relationships between co-expression modules. BMC Syst. Biol. 1 (2007) 54
    • (2007) BMC Syst. Biol. , vol.1 , pp. 54
    • Langfelder, P.1    Horvath, S.2
  • 8
    • 43249117094 scopus 로고    scopus 로고
    • Functional maps of protein complexes from quantitative genetic interaction data
    • Bandyopadhyay S., Kelley R., Krogan N.J., and Ideker T. Functional maps of protein complexes from quantitative genetic interaction data. PLoS Comput. Biol. 4 4 (2008) e1000065
    • (2008) PLoS Comput. Biol. , vol.4 , Issue.4
    • Bandyopadhyay, S.1    Kelley, R.2    Krogan, N.J.3    Ideker, T.4
  • 9
    • 34247193051 scopus 로고    scopus 로고
    • Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks
    • Ulitsky I., and Shamir R. Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks. Mol. Syst. Biol. 3 (2007) 104
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 104
    • Ulitsky, I.1    Shamir, R.2
  • 11
    • 0034011051 scopus 로고    scopus 로고
    • Multiple functions of p27(Kip1) and its alterations in tumor cells: a review
    • Sgambato A., Cittadini A., Faraglia B., and Weinstein I.B. Multiple functions of p27(Kip1) and its alterations in tumor cells: a review. J. Cell Physiol. 183 1 (2000) 18-27
    • (2000) J. Cell Physiol. , vol.183 , Issue.1 , pp. 18-27
    • Sgambato, A.1    Cittadini, A.2    Faraglia, B.3    Weinstein, I.B.4
  • 12
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene
    • Aoki K., and Taketo M.M. Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J. Cell Sci. 120 Pt. 19 (2007) 3327-3335
    • (2007) J. Cell Sci. , vol.120 , Issue.PART 19 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 14
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin W.C., Lin F.T., and Nevins J.R. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 15 14 (2001) 1833-1844
    • (2001) Genes Dev. , vol.15 , Issue.14 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 15
    • 33646047403 scopus 로고    scopus 로고
    • E2F1-induced apoptosis: turning killers into therapeutics
    • Stanelle J., and Putzer B.M. E2F1-induced apoptosis: turning killers into therapeutics. Trends Mol. Med. 12 4 (2006) 177-185
    • (2006) Trends Mol. Med. , vol.12 , Issue.4 , pp. 177-185
    • Stanelle, J.1    Putzer, B.M.2
  • 16
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan M.B., and Bartek J. Cell-cycle checkpoints and cancer. Nature 432 7015 (2004) 316-323
    • (2004) Nature , vol.432 , Issue.7015 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 17
    • 0030910037 scopus 로고    scopus 로고
    • p53 and ATM: cell cycle, cell death, and cancer
    • Morgan S.E., and Kastan M.B. p53 and ATM: cell cycle, cell death, and cancer. Adv. Cancer Res. 71 (1997) 1-25
    • (1997) Adv. Cancer Res. , vol.71 , pp. 1-25
    • Morgan, S.E.1    Kastan, M.B.2
  • 18
    • 0027983669 scopus 로고
    • Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
    • Cho Y., Gorina S., Jeffrey P.D., and Pavletich N.P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265 5170 (1994) 346-355
    • (1994) Science , vol.265 , Issue.5170 , pp. 346-355
    • Cho, Y.1    Gorina, S.2    Jeffrey, P.D.3    Pavletich, N.P.4
  • 20
    • 0025193635 scopus 로고
    • Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
    • Raycroft L., Wu H.Y., and Lozano G. Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene. Science 249 4972 (1990) 1049-1051
    • (1990) Science , vol.249 , Issue.4972 , pp. 1049-1051
    • Raycroft, L.1    Wu, H.Y.2    Lozano, G.3
  • 22
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • Cavallaro U., and Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat. Rev. Cancer 4 2 (2004) 118-132
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.2 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 23
    • 23844543408 scopus 로고    scopus 로고
    • Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation
    • Nathke I. Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation. Biochem. Soc. Trans. 33 Pt. 4 (2005) 694-697
    • (2005) Biochem. Soc. Trans. , vol.33 , Issue.PART 4 , pp. 694-697
    • Nathke, I.1
  • 24
    • 0035837241 scopus 로고    scopus 로고
    • The role of tetramerization in p53 function
    • Chene P. The role of tetramerization in p53 function. Oncogene 20 21 (2001) 2611-2617
    • (2001) Oncogene , vol.20 , Issue.21 , pp. 2611-2617
    • Chene, P.1
  • 25
    • 11044222422 scopus 로고    scopus 로고
    • Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage
    • Yoshida K., and Miki Y. Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage. Cancer Sci. 95 11 (2004) 866-871
    • (2004) Cancer Sci. , vol.95 , Issue.11 , pp. 866-871
    • Yoshida, K.1    Miki, Y.2
  • 26
    • 3543144346 scopus 로고    scopus 로고
    • E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis 1 1 American Cancer Society (ES Knudsen) and NIH (grants CA98601, ES11047, ES07784, CA16672, and T32ESO7247)
    • Powers J.T., Hong S.K., Mayhew C.N., Rogers P.M., Knudsen E.S., and Johnson D.G. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis 1 1 American Cancer Society (ES Knudsen) and NIH (grants CA98601, ES11047, ES07784, CA16672, and T32ESO7247). Mol. Cancer Res. 2 4 (2004) 203-214
    • (2004) Mol. Cancer Res. , vol.2 , Issue.4 , pp. 203-214
    • Powers, J.T.1    Hong, S.K.2    Mayhew, C.N.3    Rogers, P.M.4    Knudsen, E.S.5    Johnson, D.G.6
  • 27
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B., and Kinzler K.W. Cancer genes and the pathways they control. Nat. Med. 10 8 (2004) 789-799
    • (2004) Nat. Med. , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 28
    • 67649982444 scopus 로고    scopus 로고
    • Hill M: http://embryology.med.unsw.edu.au/DNA/DNA10.htm. 1999.
    • (1999)
    • Hill, M.1
  • 29
    • 0033599012 scopus 로고    scopus 로고
    • The breast cancer gene database: a collaborative information resource
    • Baasiri R.A., Glasser S.R., Steffen D.L., and Wheeler D.A. The breast cancer gene database: a collaborative information resource. Oncogene 18 56 (1999) 7958-7965
    • (1999) Oncogene , vol.18 , Issue.56 , pp. 7958-7965
    • Baasiri, R.A.1    Glasser, S.R.2    Steffen, D.L.3    Wheeler, D.A.4
  • 30
    • 0344464738 scopus 로고    scopus 로고
    • TSGDB: a database system for tumor suppressor genes
    • Yang Y., and Fu L.M. TSGDB: a database system for tumor suppressor genes. Bioinformatics 19 17 (2003) 2311-2312
    • (2003) Bioinformatics , vol.19 , Issue.17 , pp. 2311-2312
    • Yang, Y.1    Fu, L.M.2
  • 32
    • 33846859096 scopus 로고    scopus 로고
    • IGF1R signalling and its inhibition
    • Riedemann J., and Macaulay V.M. IGF1R signalling and its inhibition. Endocr. Relat. Cancer 13 Suppl. 1 (2006) S33-S43
    • (2006) Endocr. Relat. Cancer , vol.13 , Issue.SUPPL. 1
    • Riedemann, J.1    Macaulay, V.M.2
  • 33
    • 0032521210 scopus 로고    scopus 로고
    • Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer
    • Resnik J.L., Reichart D.B., Huey K., Webster N.J., and Seely B.L. Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer. Cancer Res. 58 6 (1998) 1159-1164
    • (1998) Cancer Res. , vol.58 , Issue.6 , pp. 1159-1164
    • Resnik, J.L.1    Reichart, D.B.2    Huey, K.3    Webster, N.J.4    Seely, B.L.5
  • 34
    • 13444266370 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
    • Hamosh A., Scott A.F., Amberger J.S., Bocchini C.A., and McKusick V.A. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res. 33 Database issue (2005) D514-D517
    • (2005) Nucleic Acids Res. , vol.33 , Issue.Database issue
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.S.3    Bocchini, C.A.4    McKusick, V.A.5
  • 35
    • 0035257202 scopus 로고    scopus 로고
    • Human genetics: affairs of the heart
    • Patterson M. Human genetics: affairs of the heart. Nature Rev. Genet. 2 (2001) 86
    • (2001) Nature Rev. Genet. , vol.2 , pp. 86
    • Patterson, M.1
  • 36
    • 0035841636 scopus 로고    scopus 로고
    • Cardiomyopathies: from genetics to the prospect of treatment
    • Franz W.M., Muller O.J., and Katus H.A. Cardiomyopathies: from genetics to the prospect of treatment. Lancet 358 9293 (2001) 1627-1637
    • (2001) Lancet , vol.358 , Issue.9293 , pp. 1627-1637
    • Franz, W.M.1    Muller, O.J.2    Katus, H.A.3
  • 40
    • 58349102521 scopus 로고    scopus 로고
    • Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy
    • Wang L., Sun F., and Chen T. Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy. Genome Biol. 9 12 (2008) R174
    • (2008) Genome Biol. , vol.9 , Issue.12
    • Wang, L.1    Sun, F.2    Chen, T.3
  • 41
    • 45549107329 scopus 로고    scopus 로고
    • Use and misuse of the gene ontology annotations
    • Rhee S.Y., Wood V., Dolinski K., and Draghici S. Use and misuse of the gene ontology annotations. Nat. Rev. Genet. 9 7 (2008) 509-515
    • (2008) Nat. Rev. Genet. , vol.9 , Issue.7 , pp. 509-515
    • Rhee, S.Y.1    Wood, V.2    Dolinski, K.3    Draghici, S.4
  • 46
    • 0346366819 scopus 로고    scopus 로고
    • Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains
    • Xing Y., Xu Q., and Lee C. Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains. FEBS Lett. 555 3 (2003) 572-578
    • (2003) FEBS Lett. , vol.555 , Issue.3 , pp. 572-578
    • Xing, Y.1    Xu, Q.2    Lee, C.3
  • 47
    • 0033472709 scopus 로고    scopus 로고
    • Resampling-based false discovery rate controlling multiple test procedures for correlated test statistics
    • Yekutieli D., and Benjamini Y. Resampling-based false discovery rate controlling multiple test procedures for correlated test statistics. J. Stat. Plan. Inference 82 1-2 (1999) 171-196
    • (1999) J. Stat. Plan. Inference , vol.82 , Issue.1-2 , pp. 171-196
    • Yekutieli, D.1    Benjamini, Y.2
  • 48
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. 57 1 (1995) 289-300
    • (1995) J. R. Stat. Soc. , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 49
    • 4444294164 scopus 로고    scopus 로고
    • Improving false discovery rate estimation
    • Pounds S., and Cheng C. Improving false discovery rate estimation. Bioinformatics 20 11 (2004) 1737-1745
    • (2004) Bioinformatics , vol.20 , Issue.11 , pp. 1737-1745
    • Pounds, S.1    Cheng, C.2
  • 50
    • 0043028206 scopus 로고    scopus 로고
    • Mutual-information-based registration of medical images: a survey
    • Pluim J.P., Maintz J.B., and Viergever M.A. Mutual-information-based registration of medical images: a survey. IEEE Trans. Med. Imaging 22 8 (2003) 986-1004
    • (2003) IEEE Trans. Med. Imaging , vol.22 , Issue.8 , pp. 986-1004
    • Pluim, J.P.1    Maintz, J.B.2    Viergever, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.