Organocatalytic conjugate addition of malonates to α,β- unsaturated aldehydes: Asymmetric formal synthesis of (-)-paroxetine, chiral lactams, and lactones

Angewandte Chemie - International Edition

Volumn 45, Issue 26, 2006, Pages 4305-4309

  Brandau, Sven ^a   Landa, Aitor ^a   Franzén, Johan ^a   Marigo, Mauro ^a   Jørgensen, Karl Anker ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Asymmetric; Lactams; Lactones; Malonates; Organocatalysis; Synthesis

Indexed keywords

ASYMMETRIC; LACTAMS; LACTONES; MALONATES; ORGANOCATALYSIS;

CATALYSIS; CHELATION; COMPLEXATION; SYNTHESIS (CHEMICAL);

DRUG PRODUCTS;

ALDEHYDE; ANTIDEPRESSANT AGENT; LACTAM; LACTONE; MALONIC ACID DERIVATIVE; PAROXETINE; SOLVENT;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALDEHYDES; ANTIDEPRESSIVE AGENTS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; LACTAMS; LACTONES; MALONATES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PAROXETINE; SOLVENTS; STEREOISOMERISM;

EID: 33746290813     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200601025     Document Type: Article

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