Recepteur d'origine nantais tyrosine kinase is a direct target of hypoxia-inducible factor-1α-mediated invasion of breast carcinoma cells

Journal of Biological Chemistry

Volumn 284, Issue 21, 2009, Pages 14001-14010

  Thangasamy, Amalraj ^a   Rogge, Jessica ^a   Ammanamanchi, Sudhakar ^a,b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b University of Texas Health Science Center at San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER CELLS; BREAST CARCINOMA CELLS; CARCINOMA CELLS; CELL LINES; CHROMATIN IMMUNOPRECIPITATION ANALYSIS; HYPOXIA-INDUCIBLE FACTOR 1; MOLECULAR TARGETS; OVER-EXPRESSION; RON TYROSINE KINASE; SHORT HAIRPIN RNA; SITE DIRECTED MUTAGENESIS; TUMOR CELL LINES; TYROSINE KINASE;

AMINO ACIDS; BINDING ENERGY; BINDING SITES; CELL CULTURE; CELL MEMBRANES; GENE EXPRESSION; MACROPHAGES; NUCLEIC ACIDS; RNA; TUMORS;

TARGETS;

ECHINOMYCIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MACROPHAGE STIMULATING PROTEIN; PROTEIN; RECEPTEUR D ORIGINE NANTAIS; SHORT HAIRPIN RNA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; CELL EXTRACT; HIF1A PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; RON PROTEIN; SCATTER FACTOR; SMALL INTERFERING RNA;

ARTICLE; BINDING SITE; BREAST CARCINOMA; CANCER INVASION; CARCINOMA CELL; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS; BREAST TUMOR; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE SILENCING; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; CELL EXTRACTS; CELL LINE, TUMOR; ECHINOMYCIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEPATOCYTE GROWTH FACTOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOPLASM INVASIVENESS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, SMALL INTERFERING;

EID: 67649774148     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809320200     Document Type: Article

References (22)

1. Kimbro, K. S., and Simons, J. W. (2006) Endocr. Relat Cancer 13, 739-749
2. Bos, R., Vander Groep, P., Greijer, A. E., Shvartis, A., Meijer, S., Pinedo, H. M., Semenzi, G. L., Van Diest, P. J., and Van der Wall, E. (2003) Cancer 97, 1573-1581
3. Vleugel, M. M., Greijer, A. E., Shvarts, A., Van der groep, P., Van Berkel, M., Aarbodem, Y., Van Tinteren, H., Harris, A. L., Van Diest, P. J., and Van der Wall, E. (2005) J. Clin. Pathol. (Lond.) 58, 172-177
4. Gruber, G., Greiner, R. H., Hlushchuk, R., Aebersold, D. M., Altermatt, H. J., Berclaz, G, and Djonov, V. (2004) Breast Cancer Res. 6, R191-R198
5. Dales, J. P., Garcia, S., Meunier-Carpentier, S., Andrae-Meyer, L., Haddad, O., Lavaut, M. N., Allasia, C., Bonnier, P., and Charpin, C. (2005) Int. J. Cancer 116, 731-739
6. Kronbald, A., Sirstrom, K., Ryden, L., Nordenskjold, B., and Landberg, G. (2006) Int. J. Cancer 118, 2609-2616
7. Bos, R., Zhong, H., Hanrahan, C. F., Mommers, E. C. M., Semenza, G. L., Pinedo, H. M., Abeloff, M. D., Simons, J. W., Van diest, P. J., and Van der Wall, E. (2001) J. Natl. Cancer Inst. 93, 309-314
8. Yamamoto, Y., Ibusuki, M., Okumura, Y., Kawasoe, T., Kai, K., Iyama, K, and Iwase, H. (2008) Breast Cancer Res. Treat. 110, 465-475
9. Hiraga, T., Kizaka-Kondoh, S., Hirota, K., Hiraoka, M., and Yoneda, T. (2007) Cancer Res. 67, 4157-4163
10. Liao, D., Corele, C., Seagroves, T. N., and Johnson, R. (2007) Cancer Res. 67, 563-572
11. Fukuda, R., Hirota, K., Fan, F., Jung, Y. D., Ellis, L. M., and Semenza, G. L. (2002) J. Biol. Chem. 277, 38295-38311
12. Zhong. H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M.-M., Simons, J. W., and Semenza, G. L. (2000) Cancer Res. 60, 1541-1545
13. Wang, M. H., Lee, W., Luo, Y. L., Weis, M. T., and Yao, H. P. (2007) J. Pathol. 213, 402-411
14. Leonis, M. A., Thobe, M. N., and Waltz, S. (2007) Future Oncol. 3, 441-448
15. Zinser, G. M., Leonis, M. A., Toney, K., Pathrose, P., Thobe, M., Kader, S. A., Peace, B. F., Beauman, S. R., Collins, M. H., and Waltz, S. E. (2006) Cancer Res. 66, 11967-11974
16. Lee, W.-Y., Chen, H. H., Chow, N. H., Su, W. C., Lin, P. W., and Guo, H. R. (2005) Clin. Cancer Res. 11, 2222-2228
17. Thangasamy, A., Rogge, I., and Ammanamanchi, S. (2008) J. Biol. Chem. 283, 5335-5343
18. Kong, D., Park., E. J., Stephen, A. G., Calvani, M., Cardellina, J. H., Monks, A., Fisher, R. J., Shoemaker, R. H., and Melillo, G. (2005) Cancer Res. 65, 9047-9055
19. Danilkovitch-Miagkova, A., Miagkov, A., Skeel, A., Nakaigawa, N., Zbar, B., and Leonard, E. J. (2001) Mol. Cell Biol. 21, 5857-5868
20. Del Gatto, F., Gilbert, E., Ronsin, C., and Breathnach, R. (1995) Biochim. Biophys. Acta 1263, 93-95
21. Narasimhan, M., and Ammanamanchi, S. (2008) Cancer Res. 68, 5185-5192
22. Welm, A. L., Sneddon, J. B., Taylor, C., Nuyten, D. S. A., Van de Vijver, M. J., Hasegawa, B. H., and Bishop, M. J. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 7570-7575