Acid sphingomyelinase deficiency prevents diet-induced hepatic triacylglycerol accumulation and hyperglycemia in mice

Journal of Biological Chemistry

Volumn 284, Issue 13, 2009, Pages 8359-8368

  Deevska, Gergana M ^a   Rozenova, Krassimira A ^a   Giltiay, Natalia V ^a   Chambers, Melissa A ^a   White, James ^a   Boyanovsky, Boris B ^a   Wei, Jia ^a   Daugherty, Alan ^b   Smart, Eric J ^a   Reid, Michael B ^a   Merrill Jr , Alfred H ^a   Nikolova Karakashian, Mariana ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SPHINGOMYELINASE; BODY FATS; CERAMIDE; GLUCOSE METABOLISM; HEPATIC TRIACYLGLYCEROL; HEPATOCYTES; HYPERCHOLESTEROLEMIA; IN-VIVO; INSULIN RESISTANCE; LOW DENSITY LIPOPROTEIN RECEPTORS; RATE-LIMITING ENZYMES; SATURATED FATS; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; SPHINGOLIPIDS; SPHINGOMYELIN; TRIACYL GLYCERIDE;

ACIDS; AGRICULTURAL PRODUCTS; AMIDES; AMINO ACIDS; ECOLOGY; FATTY ACIDS; GLUCOSE; GLYCEROL; INSULIN; LIPIDS; NUTRITION; PHYSIOLOGY;

ACID RESISTANCE;

GLUCOSE; LOW DENSITY LIPOPROTEIN RECEPTOR; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; CHOLESTEROL DIET; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENOTYPE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; IN VIVO STUDY; INSULIN RESISTANCE; LIPID DIET; LIPID STORAGE; LIVER CELL; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; FOOD, FORMULATED; GLUCOSE; HEPATOCYTES; HYPERGLYCEMIA; INSULIN RESISTANCE; LIVER; MICE; MICE, KNOCKOUT; PALMITATES; RECEPTORS, LDL; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS; SPHINGOMYELIN PHOSPHODIESTERASE; TRIGLYCERIDES;

MUS;

EID: 67649763475     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807800200     Document Type: Article

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