Acrylamide-induced astrogliotic and apoptotic responses in human astrocytoma cells

Toxicology in Vitro

Volumn 23, Issue 5, 2009, Pages 855-861

  Chen, Jong Hang ^a   Wu, Kuen Yuh ^a   Chiu, Ing Ming ^b,c   Tsou, Tsui Chun ^b   Chou, Chin Cheng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Acrylamide; Apoptosis; Astrocytic cells; Astrogliosis; GFAP

Indexed keywords

ACRYLAMIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; LACTATE DEHYDROGENASE; PROTEIN P53; SERINE;

APOPTOSIS; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; ASTROCYTOSIS; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NEUROBLASTOMA CELL; PROTEIN PHOSPHORYLATION;

ACRYLAMIDE; APOPTOSIS; ASTROCYTES; ASTROCYTOMA; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; L-LACTATE DEHYDROGENASE; NEUROBLASTOMA; PHOSPHORYLATION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 67649494327     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.04.015     Document Type: Article

References (36)

1. Andersson M.N., Walum E., Kjellstrand P., and Forsby A. Acrylamide-induced effects on general and neurospecific cellular functions during exposure and recovery. Cell Biology and Toxicology 19 (2003) 43-51
2. Aschner M., Cao C., Wu Q., and Friedman M.A. The acute effects of acrylamide on astrocyte functions. Annals of the New York Academy of Sciences 993 (2003) 296-304
3. Aschner M., Wu Q., and Friedman M.A. Effects of acrylamide on primary neonatal rat astrocyte functions. Annals of the New York Academy of Sciences 1053 (2005) 444-454
4. Chen Y., Vartiainen N.E., Ying W., Dhan P.H., Koistinaho J., and Swanson R.A. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. Journal of Neurochemistry 77 (2001) 1601-1610
5. Chock V., and Giffard R. The central nervous system and inflammation: astrocytes. In: Yenari M.A., and Giffard R.G. (Eds). Glia and Inflammation in Neurodegenerative Disease (2006), Nova Science Publishers, Inc., New York 25-40
6. Cookson M.R., and Pentreath V.W. Alterations in the glial fibrillary acidic protein content of primary astrocyte cultures for evaluation of glial cell toxicity. Toxicology in Vitro 8 (1994) 351-359
7. Crofton K.M., Padilla S., Tilson H.A., Anthony D.C., Raymer J.H., and MacPhail R.C. The impact of dose rate on the neurotoxicity of acrylamide: the interaction of administered dose, target tissue concentrations, tissue damage, and functional effects. Toxicology and Applied Pharmacology 139 (1996) 163-176
8. Deng H., He F., Zhang S., Calleman C.J., and Costa L.G. Quantitative measurements of vibration threshold in healthy adults and acrylamide workers. International Archives of Occupational and Environmental Health 65 (1993) 53-56
9. DeJongh J., Andersson M.N., Ploeger B.A., and Forsby A. Estimation of systemic toxicity of acrylamide by integration of in vitro toxicity data with kinetic simulations. Toxicology and Applied Pharmacology 158 (1999) 261-268
10. Edwards P.M., and Parker V.H. A simple, sensitive, and objective method for early assessment of acrylamide neuropathy in rats. Toxicology and Applied Pharmacology 40 (1977) 589-591
11. Eng L.F., Ghirnikar R.S., and Lee Y.L. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochemical Research 25 (2000) 1439-1451
12. Friedman M.A., Dulak L.H., and Stedham M.A. A lifetime oncogenicity study in rats with acrylamide. Fundamental and Applied Toxicology 27 (1995) 95-105
13. Friedman M. Chemistry, biochemistry, and safety of acrylamide. A review. Journal of Agricultural and Food Chemistry 51 (2003) 4504-4526
14. Garey J., Ferguson S.A., and Paule M.G. Developmental and behavioral effects of acrylamide in Fischer 344 rats. Neurotoxicology and Teratology 27 (2005) 553-563
15. Hartley C.L., Anderson V.E., Anderton B.H., and Robertson J. Acrylamide and 2, 5-hexanedione induce collapse of neurofilaments in SH-SY5Y human neuroblastoma cells to form perikaryal inclusion bodies. Neuropathology and Applied Neurobiology 23 (1997) 364-372
16. Holden L.J., and Coleman M.D. Assessment of the astrogliotic responses of three human astrocytoma cell lines to ethanol, trimethyl tin chloride and acrylamide. Toxicology 241 (2007) 75-83
17. International Agency for Research on Cancer (IARC). Acrylamide, IARC monographs on the evaluation of carcinogenic risks to humans. Some Industrial Chemicals 60 (1994) 389-433
18. Johnson K.A., Gorzinski S.J., Bodner K.M., Campbell R.A., Wolf C.H., Friedman M.A., and Mast R.W. Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats. Toxicology and Applied Pharmacology 85 (1986) 154-168
19. Khanna P., and Nehru B. Antioxidant enzymatic system in neuronal and glial cells enriched fractions of rat brain after aluminum exposure. Cellular and Molecular Neurobiology 27 (2007) 959-969
20. Konings E.J.M., Bears A.J., van Klaveren J.D., Spanjer M.C., Rensen P.M., Hiemstra M., van Kooij J.A., and Peters P.W.J. Acrylamide exposure from foods of the Dutch population and an assessment of the consequent risks. Food and Chemical Toxicology 41 (2003) 1569-1579
21. Lehning E.J., Persaud A., Dyer K.R., Jortner B.S., and LoPachin R.M. Biochemical and morphologic characterization of acrylamide peripheral neuropathy. Toxicology and Applied Pharmacology 151 (1998) 211-221
22. Liu J.M., Mao B.Y., Hong S., Liu Y.H., and Wang X.J. The postoperative brain tumour stem cell (BTSC) niche and cancer recurrence. Advances in Therapy 25 (2008) 389-398
23. Liu Y., Ray S.K., Yang X.Q., Leybman V.L., and Chiu I.M. A splice variant of E2-2 basic helix-loop-helix protein represses the brain-specific fibroblast growth factor 1 promoter through the binding to an imperfect E-box. Journal of Biological Chemistry 273 (1998) 19269-19276
24. LoPachin P.M. The role of fast axonal transport in acrylamide pathophysiology: mechanism or epiphenomenon?. NeuroToxicology 23 (2002) 253-257
25. LoPachin P.M., Balaban C.D., and Ross J.F. Acrylamide axonopathy revisited. Toxicology and Applied Pharmacology 188 (2003) 135-153
26. Matyja E., Grajkowska W., Taraszewska A., Marchel A., Bojarski P., and Nauman P. Advanced reactive astrogliosis associated with hemangioblastoma versus astroglial-vascular neoplasm ("angioglioma"). Folia Neuropathologica 45 (2007) 120-125
27. Myers R.L., Ray S.K., Eldridge R., Chotani M.A., and Chiu I.M. Functional characterization of the brain-specific FGF-1 promoter, FGF-1.B. Journal of Biological Chemistry 270 (1995) 8257-8266
28. Okuno T., Matsuoka M., Sumizawa T., and Igisu H. Involvement of the extracellular signal-regulated protein kinase pathway in phosphorylation of p53 protein and exerting cytotoxicity in human neuroblastoma cells (SH-SY5Y) exposed to acrylamide. Archives of Toxicology 80 (2006) 146-153
29. Rice J.M. The carcinogenicity of acrylamide. Mutation Research 580 (2005) 3-20
30. Ray S.K., Yang X.Q., and Chiu I.M. Transcriptional activation of fibroblast growth factor 1.B promoter is mediated through an 18-base pair cis-acting element. Journal of Biological Chemistry 272 (1997) 7546-7555
31. Smith C.J., Perfetti T.A., Rumple M.A., Rodgman A., and Doolittle D.J. IARC group 2A carcinogens' reported in cigarette mainstream smoke. Food and Chemical Toxicology 39 (2001) 183-205
32. Sumizawa T., and Igisu H. Apoptosis induced by acrylamide in SH-SY5Y cells. Archives of Toxicology 81 (2007) 279-282
33. Svensson K., Abramsson L., Becker W., Glynn A., Hellenas K.E., Lind Y., and Rosen J. Dietary intake of acrylamide in Sweden. Food and Chemical Toxicology 41 (2003) 1581-1586
34. Tareke E., Rydberg P., Karlsson P., Eriksson S., and Tornqvist M. Acrylamide: a cooking carcinogen?. Chemical Research in Toxicology 13 (2000) 517-522
35. Tibbetts R.S., Brumbaugh K.M., Williams J.M., Sarkaria J.N., Cliby W.A., Shieh S.Y., Taya Y., Prives C., and Abraham R.T. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes and Development 13 (1999) 152-157
36. Vazquez A., Bond E.E., Levine A.J., and Bond G. The genetics of the p53 pathway, apoptosis and cancer therapy. Nature Reviews Drug Discovery 7 (2008) 979-987