The diabetogenic effects of excessive ethanol: Reducing β-cell mass, decreasing phosphatidylinositol 3-kinase activity and GLUT-4 expression in rats

British Journal of Nutrition

Volumn 101, Issue 10, 2009, Pages 1467-1473

  Zhao, Li Na ^a   Hao, Li Ping ^a   Yang, Xue Feng ^a   Ying, Chen Jiang ^a   Yu, Dong ^a   Sun, Xiu Fa ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Ethanol; GLUT 4; Phosphatidylinositol 3 kinase

Indexed keywords

ALCOHOL; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE;

ALCOHOL ABUSE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; ENZYME INHIBITION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; INSULIN RESISTANCE; INSULIN SENSITIVITY; MORPHOMETRICS; NONHUMAN; PANCREAS INJURY; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALCOHOL DRINKING; ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; ETHANOL; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 4; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-SECRETING CELLS; RANDOM ALLOCATION; RATS; RATS, WISTAR; RNA, MESSENGER;

RATTUS; RATTUS NORVEGICUS;

EID: 67649419157     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508094646     Document Type: Article

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