Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance

Diabetologia

Volumn 46, Issue 9, 2003, Pages 1211-1219

  Ferrannini, E ^a,b   Gastaldelli, A ^a   Miyazaki, Y ^b   Matsuda, M ^b   Pettiti, M ^a   Natali, A ^a   Mari, A ^c   DeFronzo, R A ^b  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c CNR   (Italy)

Author keywords

Beta cell function; IGT; Insulin resistance; Insulin secretion; Mathematical modelling

Indexed keywords

C PEPTIDE; GLUCOSE;

ADULT; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GLUCONEOGENESIS; GLUCOSE TOLERANCE TEST; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; OBSERVATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADULT; BLOOD GLUCOSE; C-PEPTIDE; FASTING; FEMALE; GLUCOSE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; KINETICS; MALE; REFERENCE VALUES;

EID: 0141483058     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1169-6     Document Type: Article

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