An in vivo and in vitro comparison of CYP gene induction in mice using liver slices and quantitative RT-PCR

Toxicology in Vitro

Volumn 20, Issue 1, 2006, Pages 125-131

  Martignoni, Marcella ^a   De Kanter, Ruben ^a   Grossi, Pietro ^a   Saturno, Grazia ^a   Barbaria, Elena ^a   Monshouwer, Mario ^a  

^a Preclinical Development   (Italy)

Author keywords

CYP induction; In vitro; Liver; Methods; Mouse; Slices

Indexed keywords

BETA NAPHTHOFLAVONE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; DEXAMETHASONE; MESSENGER RNA; PHENOBARBITAL; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE INDUCTION; IN VITRO STUDY; IN VIVO STUDY; LIVER SLICE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAFETY; TIME;

ANIMALS; BETA-NAPHTHOFLAVONE; BIOLOGICAL ASSAY; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIVER; MALE; MICE; MICE, INBRED STRAINS; PHENOBARBITAL; RNA, MESSENGER;

ANIMALIA;

EID: 29144489368     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.06.040     Document Type: Article

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