A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies

Journal of Immunological Methods

Volumn 318, Issue 1-2, 2007, Pages 113-124

  Li, Jiandong ^a   Menzel, Christian ^a   Meier, Doris ^a   Zhang, Congcong ^a   Dübel, Stefan ^a   Jostock, Thomas ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

EMCV IRES; IgG expression; Promoter; Stable expression

Indexed keywords

CHIMERIC ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PHENYLALANINE; PLASMID VECTOR; POLYPEPTIDE; PROLINE; RECOMBINANT ANTIBODY; TYROSINE;

ANIMAL CELL; ANTIBODY ENGINEERING; ANTIBODY PRODUCTION; ARTICLE; CELL LINE; CHO CELL; CISTRON; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EXPRESSION VECTOR; FLUORESCENCE ACTIVATED CELL SORTING; GENE CASSETTE; GENE CONSTRUCT; GENE EXPRESSION; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE;

5' UNTRANSLATED REGIONS; ANIMALS; ANTIBODIES, MONOCLONAL; BACTERIAL PROTEINS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; CYTOMEGALOVIRUS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENCEPHALOMYOCARDITIS VIRUS; FLOW CYTOMETRY; GENE EXPRESSION; GENES, REPORTER; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; LUMINESCENT PROTEINS; MICE; MOLECULAR WEIGHT; PEPTIDE ELONGATION FACTOR 1; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; TRANSFECTION;

ENCEPHALOMYOCARDITIS VIRUS; MAMMALIA;

EID: 33845906594     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2006.10.010     Document Type: Article

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