-
1
-
-
33947720523
-
Development in motion: Helper T cells at work
-
Reiner, S. L. 2007. Development in motion: helper T cells at work. Cell 129: 33-36.
-
(2007)
Cell
, vol.129
, pp. 33-36
-
-
Reiner, S.L.1
-
2
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel, K. M., I. Djuretic, B. Tanasa, and A. Rao. 2006. Regulation of Th2 differentiation and Il4 locus accessibility. Annu. Rev. Immunol. 24: 607-656.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
3
-
-
33646012294
-
T helper cell differentiation: Regulation by cis elements and epigenetics
-
Lee, G. R., S. T. Kim, C. G. Spilianakis, P. E. Fields, and R. A. Flavell. 2006. T helper cell differentiation: regulation by cis elements and epigenetics. Immunity 24: 369-379.
-
(2006)
Immunity
, vol.24
, pp. 369-379
-
-
Lee, G.R.1
Kim, S.T.2
Spilianakis, C.G.3
Fields, P.E.4
Flavell, R.A.5
-
5
-
-
3843060051
-
Chromatin landscape dynamics of the Il4 -Il13 locus during T helper 1 and 2 development
-
Baguet, A., and M. Bix. 2004. Chromatin landscape dynamics of the Il4 -Il13 locus during T helper 1 and 2 development. Proc. Natl. Acad. Sci. USA 101: 11410-11415.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11410-11415
-
-
Baguet, A.1
Bix, M.2
-
6
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita M., M. Ukai-Tadenuma, M. Kimura, M. Omori, M. Inami, M. Taniguchi, and T. Nakayama. 2002. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J. Biol. Chem. 277: 42399-42408.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42399-42408
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Kimura, M.3
Omori, M.4
Inami, M.5
Taniguchi, M.6
Nakayama, T.7
-
7
-
-
0036305450
-
TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni, O., D. Lee, F. Macian, S. J. Szabo, L. H. Glimcher, and A. Rao. 2002. TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 3: 643-651.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 643-651
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
8
-
-
0037100265
-
Cutting edge: Changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation
-
Fields, P. E., S. T. Kim, and R. A. Flavell. 2002. Cutting edge: changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation. J. Immunol. 169: 647-650.
-
(2002)
J. Immunol.
, vol.169
, pp. 647-650
-
-
Fields, P.E.1
Kim, S.T.2
Flavell, R.A.3
-
9
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. 2002. DNA methylation patterns and epigenetic memory. Genes Dev. 16: 6-21.
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
10
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenisch, R., and A. Bird. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33(Suppl): 245-254.
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
11
-
-
0036279221
-
Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
-
Lee, D. U., S. Agarwal, and A. Rao. 2002. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity 16: 649-660.
-
(2002)
Immunity
, vol.16
, pp. 649-660
-
-
Lee, D.U.1
Agarwal, S.2
Rao, A.3
-
12
-
-
10344234192
-
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
-
Fields, P. E., G. R. Lee, S. T. Kim, V. Bartsevich, and R. A. Flavell. 2004. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity 21: 865-876.
-
(2004)
Immunity
, vol.21
, pp. 865-876
-
-
Fields, P.E.1
Lee, G.R.2
Kim, S.T.3
Bartsevich, V.4
Flavell, R.A.5
-
13
-
-
0346752253
-
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
-
Makar, K. W., M. Pérez-Melgosa, M. Shnyreva, W. M. Weaver, D. R. Fitzpatrick, and C. B. Wilson. 2003. Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells. Nat. Immunol. 4: 1183-1190.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1183-1190
-
-
Makar, K.W.1
Pérez-Melgosa, M.2
Shnyreva, M.3
Weaver, W.M.4
Fitzpatrick, D.R.5
Wilson, C.B.6
-
14
-
-
4644231710
-
DNA methylation is a nonredundant repressor of the Th2 effector program
-
Makar, K. W., and C. B. Wilson. 2004. DNA methylation is a nonredundant repressor of the Th2 effector program. J. Immunol. 173: 4402-4406.
-
(2004)
J. Immunol.
, vol.173
, pp. 4402-4406
-
-
Makar, K.W.1
Wilson, C.B.2
-
15
-
-
0037340215
-
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
-
Bruniquel, D., and R. H. Schwartz. 2003. Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat. Immunol. 4: 235-240.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 235-240
-
-
Bruniquel, D.1
Schwartz, R.H.2
-
16
-
-
33646058925
-
Rapid demethylation of the IFN-γ gene occurs in memory but not naive CD8 T cells
-
Kersh, E. N., D. R. Fitzpatrick, K. Murali-Krishna, J. Shires, S. H. Speck, J. M. Boss, and R. Ahmed. 2006. Rapid demethylation of the IFN-γ gene occurs in memory but not naive CD8 T cells. J. Immunol. 176: 4083-4093.
-
(2006)
J. Immunol.
, vol.176
, pp. 4083-4093
-
-
Kersh, E.N.1
Fitzpatrick, D.R.2
Murali-Krishna, K.3
Shires, J.4
Speck, S.H.5
Boss, J.M.6
Ahmed, R.7
-
17
-
-
36749029364
-
Demethylation of a specific hypersensitive site in the Th2 locus control region
-
Kim, S. T., P. E. Fields, and R. A. Flavell. 2007. Demethylation of a specific hypersensitive site in the Th2 locus control region. Proc. Natl. Acad. Sci. USA 104: 17052-17057.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17052-17057
-
-
Kim, S.T.1
Fields, P.E.2
Flavell, R.A.3
-
18
-
-
0034616398
-
Identification of a coordinate regulator of interleukins 4, 13 and 5 by cross-species sequence comparisons
-
Loots, G. G., R. M. Locksley, C. M. Blankespoor, Z. E. Wang, W. Miller, E. M. Rubin, and K. A. Frazer. 2000. Identification of a coordinate regulator of interleukins 4, 13 and 5 by cross-species sequence comparisons. Science 288: 136-140.
-
(2000)
Science
, vol.288
, pp. 136-140
-
-
Loots, G.G.1
Locksley, R.M.2
Blankespoor, C.M.3
Wang, Z.E.4
Miller, W.5
Rubin, E.M.6
Frazer, K.A.7
-
19
-
-
0031593671
-
Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region
-
Takemoto, N., N. Koyano-Nakagawa, T. Yokota, N. Arai, S. Miyatake, and K. Arai. 1998. Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region. Int. Immunol. 10: 1981-1985.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1981-1985
-
-
Takemoto, N.1
Koyano-Nakagawa, N.2
Yokota, T.3
Arai, N.4
Miyatake, S.5
Arai, K.6
-
20
-
-
0035555263
-
Deletion of a coordinate regulator of type 2 cytokine expression in mice
-
Mohrs, M., C. M. Blankespoor, Z.-E. Wang, G. G. Loots, V. Afzal, H. Hadeiba, K. Shinkai, E. M. Rubin, and R. M. Locksley. 2001. Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat. Immunol. 2: 842-847.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 842-847
-
-
Mohrs, M.1
Blankespoor, C.M.2
Wang, Z.-E.3
Loots, G.G.4
Afzal, V.5
Hadeiba, H.6
Shinkai, K.7
Rubin, E.M.8
Locksley, R.M.9
-
21
-
-
0025886982
-
+ T cells acquire specific lymphokine secretion potentials during thymic maturation
-
Bendelac, A., and R. H. Schwartz. 1991. CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation. Nature 353: 68-71. (Pubitemid 21912457)
-
(1991)
Nature
, vol.353
, Issue.6339
, pp. 68-71
-
-
Bendelac, A.1
Schwartz, R.H.2
-
23
-
-
1042269476
-
Immunologic immaturity, but high IL-4 productivity, of murine neonatal thymic CD4 single-positive T cells in the last stage of maturation
-
Koyanagi, M., K. Imanishi, Y. Arimura, H. Kato, J. Yagi, and T. Uchiyama. 2004. Immunologic immaturity, but high IL-4 productivity, of murine neonatal thymic CD4 single-positive T cells in the last stage of maturation. Int. Immunol. 16: 315-326.
-
(2004)
Int. Immunol.
, vol.16
, pp. 315-326
-
-
Koyanagi, M.1
Imanishi, K.2
Arimura, Y.3
Kato, H.4
Yagi, J.5
Uchiyama, T.6
-
25
-
-
33645962818
-
Replication initiation from a novel origin identified in the Th2 cytokine cluster locus requires a distant conserved noncoding sequence
-
Hayashida, T., M. Oda, K. Ohsawa, A. Yamaguchi, T. Hosozawa, R. M. Locksley, M. Giacca, H. Masai, and S. Miyatake. 2006. Replication initiation from a novel origin identified in the Th2 cytokine cluster locus requires a distant conserved noncoding sequence. J. Immunol. 176: 5446-5454.
-
(2006)
J. Immunol.
, vol.176
, pp. 5446-5454
-
-
Hayashida, T.1
Oda, M.2
Ohsawa, K.3
Yamaguchi, A.4
Hosozawa, T.5
Locksley, R.M.6
Giacca, M.7
Masai, H.8
Miyatake, S.9
-
27
-
-
0036345455
-
Gene silencing quantitatively controls the function of a developmental trans-activator
-
Hutchins, A. S., A. C. Mullen, H. W. Lee, K. J. Sykes, F. A. High, B. D. Hendrich, A. P. Bird, and S. L. Reiner. 2002. Gene silencing quantitatively controls the function of a developmental trans-activator. Mol. Cell 10: 81-91.
-
(2002)
Mol. Cell
, vol.10
, pp. 81-91
-
-
Hutchins, A.S.1
Mullen, A.C.2
Lee, H.W.3
Sykes, K.J.4
High, F.A.5
Hendrich, B.D.6
Bird, A.P.7
Reiner, S.L.8
-
28
-
-
27144534809
-
Cutting edge: A critical role for gene silencing in preventing excessive type 1 immunity
-
Hutchins, A. S., D. Artis, B. D. Hendrich, A. P. Bird, P. Scott, and S. L. Reiner. 2005. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. J. Immunol. 175: 5606-5610.
-
(2005)
J. Immunol.
, vol.175
, pp. 5606-5610
-
-
Hutchins, A.S.1
Artis, D.2
Hendrich, B.D.3
Bird, A.P.4
Scott, P.5
Reiner, S.L.6
-
29
-
-
59849085588
-
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation
-
Girdhari L., N. Zhang, W. van der Touw, Y. Ding, W. Ju, E. P. Bottinger, S. P. Reid, D. E. Levy, and J. S. Bromberg. 2009. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J. Immunol. 182: 259-273.
-
(2009)
J. Immunol.
, vol.182
, pp. 259-273
-
-
Girdhari, L.1
Zhang, N.2
Van Der Touw, W.3
Ding, Y.4
Ju, W.5
Bottinger, E.P.6
Reid, S.P.7
Levy, D.E.8
Bromberg, J.S.9
-
30
-
-
24744462507
-
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells
-
Koyanagi, M., A. Baguet, J. Martens, R. Margueron, T. Jenuwein, and M. Bix. 2005. EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells. J. Biol. Chem. 280: 31470-31477.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31470-31477
-
-
Koyanagi, M.1
Baguet, A.2
Martens, J.3
Margueron, R.4
Jenuwein, T.5
Bix, M.6
-
31
-
-
34250762587
-
"marks" across the locus encoding interferon-γ during the differentiation of T helper type 2 cells
-
Chang, S., and T. M. Aune. 2007. Dynamic changes in histone-methylation "marks" across the locus encoding interferon-γ during the differentiation of T helper type 2 cells. Nat. Immunol. 8; 723-731.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 723-731
-
-
Chang, S.1
Aune, T.M.2
-
32
-
-
34250773899
-
Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-γ
-
Schoenborn, J. R., M. O. Dorschner, M. Sekimata, D. M. Santer, M. Shnyreva, D. R. Fitzpatrick, J. A. Stamatoyannopoulos, and C. B. Wilson. 2007. Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-γ. Nat. Immunol. 8: 732-742.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 732-742
-
-
Schoenborn, J.R.1
Dorschner, M.O.2
Sekimata, M.3
Santer, D.M.4
Shnyreva, M.5
Fitzpatrick, D.R.6
Stamatoyannopoulos, J.A.7
Wilson, C.B.8
-
33
-
-
35649018164
-
Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes
-
D'Alessio, A. C., I. C. G. Weaver, and M. Szyf. 2007. Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes. Mol. Cell. Biol. 27: 7462-7474.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7462-7474
-
-
D'Alessio, A.C.1
Weaver, I.C.G.2
Szyf, M.3
-
34
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich, B., U. Hardeland, H.-H. Ng, J. Jiricny, and A. Bird. 1999. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401: 301-304. (Pubitemid 129515547)
-
(1999)
Nature
, vol.401
, Issue.6750
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.-H.3
Jiricny, J.4
Bird, A.5
-
35
-
-
34248170739
-
Mbd2 contributes to DNA methylation-directed repression of the Xist gene
-
Barr, H., A. Hermann, J. Berger, H.-H. Tsai, K. Adie, A. Prokhortchouk, B. Hendrich, and A. Bird. 2007. Mbd2 contributes to DNA methylation-directed repression of the Xist gene. Mol. Cell. Biol. 27: 3750-3757.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3750-3757
-
-
Barr, H.1
Hermann, A.2
Berger, J.3
Tsai, H.-H.4
Adie, K.5
Prokhortchouk, A.6
Hendrich, B.7
Bird, A.8
-
36
-
-
34347328214
-
MBD2 is required for correct spatial gene expression in the gut
-
Berger, J., O. Sansom, A. Clarke, and A. Bird. 2007. MBD2 is required for correct spatial gene expression in the gut. Mol. Cell. Biol. 27: 4049-4057.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4049-4057
-
-
Berger, J.1
Sansom, O.2
Clarke, A.3
Bird, A.4
-
37
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Metivier, R., R. Gallais, C. Tiffoche, C. Le Peron, R. Z. Jurkowska, R. P. Carmouche, D. Ibberson, P. Barath, F. Demay, G. Reid, et al. 2008. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452: 45-50.
-
(2008)
Nature
, vol.452
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
|