Effect of sugars, surfactant, and tangential flow filtration on the freeze-drying of poly(lactic acid) nanoparticles

AAPS PharmSciTech

Volumn 10, Issue 2, 2009, Pages 488-494

  Hirsjärvi, Samuli ^a,b   Peltonen, Leena ^a   Hirvonen, Jouni ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b INSERM   (France)

Author keywords

Freeze drying; Nanoparticles; Poly(lactic acid); Protective excipients; Tangential flow filtration

Indexed keywords

GLUCOSE; LACTOSE; NANOPARTICLE; POLOXAMER; POLYLACTIC ACID; SUCROSE; SUGAR; SURFACTANT; TREHALOSE; CARBOHYDRATE; EXCIPIENT; LACTIC ACID; POLYMER;

ARTICLE; CROSSFLOW FILTRATION; DISPERSION; FREEZE DRYING; PARTICLE SIZE; PURIFICATION; CHEMISTRY; ELECTRON MICROSCOPY; FILTRATION;

CARBOHYDRATES; EXCIPIENTS; FILTRATION; FREEZE DRYING; LACTIC ACID; MICROSCOPY, ELECTRON; NANOPARTICLES; POLOXAMER; POLYMERS; SURFACE-ACTIVE AGENTS;

EID: 67549107859     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9236-z     Document Type: Article

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