Formulation development of freeze-dried oligonucleotide-loaded gelatin nanoparticles

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 2, 2008, Pages 514-521

  Zillies, Jan C ^a   Zwiorek, Klaus ^a   Hoffmann, Florian ^a   Vollmar, Angelika ^a   Anchordoquy, Thomas J ^b   Winter, Gerhard ^a   Coester, Conrad ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Drug delivery; Drug targeting; Freeze drying; Gelatin nanoparticles; NF kB; Oligonucleotide

Indexed keywords

DEXTRAN 3000; EXCIPIENT; GELATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANNITOL; NANOPARTICLE; OLIGONUCLEOTIDE; POLYSORBATE 80; SUCROSE; TREHALOSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOISTURE; NONHUMAN; PARTICLE SIZE; RAT; REHYDRATION;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; FREEZE DRYING; GELATIN; LIPOPOLYSACCHARIDES; LIVER; MALE; NANOPARTICLES; NF-KAPPA B; OLIGONUCLEOTIDES; RATS; RATS, SPRAGUE-DAWLEY; SUSPENSIONS;

EID: 52949131862     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.04.026     Document Type: Article

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