Repeated aerosol delivery of carboxyl-terminal modulator protein suppresses tumor in the lungs of K-rasLA1 mice

American Journal of Respiratory and Critical Care Medicine

Volumn 179, Issue 12, 2009, Pages 1131-1140

  Hwang, Soon Kyung ^a   Lim, Hwang Tae ^a   Minai Tehrani, Arash ^a   Lee, Eun Sun ^a   Park, Jongmin ^a   Seung, Bum Park ^a   Beck Jr , George R ^b   Cho, Myung Haing ^a  

^a Seoul National University   (South Korea)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aerosol gene delivery; Carboxyl terminal modulator protein; K ras LA1 mice; Lentivirus; Lung cancer

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOXYL TERMINAL MODULATOR PROTEIN; K RAS PROTEIN; LENTIVIRUS VECTOR; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG;

AEROSOL; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CANCER INHIBITION; CANCER STAGING; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; LUNG CANCER; LUNG CARCINOGENESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TREATMENT DURATION; TREATMENT OUTCOME;

ADENOCARCINOMA; AEROSOLS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE, TUMOR; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; GENES, RAS; IN SITU NICK-END LABELING; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; TREATMENT OUTCOME;

EID: 67449090626     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200810-1553OC     Document Type: Article

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