The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease

Journal of Autoimmunity

Volumn 33, Issue 1, 2009, Pages 58-67

  Bratland, Eirik ^a,b   Bredholt, Geir ^a   Mellgren, Gunnar ^a,b   Knappskog, Per M ^a,b   Mozes, Edna ^c   Husebye, Eystein S ^a,b  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

21 Hydroxylase; Addison's disease; Adrenal cortex; Autoimmunity; Cytochrome P450

Indexed keywords

GAMMA INTERFERON; RECOMBINANT PROTEIN; STEROID 21 MONOOXYGENASE;

ADDISON DISEASE; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; INSECT CELL; INTERFERON PRODUCTION; LEPIDOPTERA; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; T LYMPHOCYTE;

ADDISON DISEASE; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; BACULOVIRIDAE; CELL LINE; CELL PROLIFERATION; CHROMATOGRAPHY, AFFINITY; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; IMMUNE SERA; IMMUNIZATION; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE; PEPTIDES; SPODOPTERA; STEROID 21-HYDROXYLASE; T-LYMPHOCYTES; TRANSGENES;

EID: 67349270927     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2009.02.018     Document Type: Article

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