Substitution of Pichia pastoris-derived recombinant proteins with mannose containing O- and N-linked glycans decreases specificity of diagnostic tests

International Archives of Allergy and Immunology

Volumn 135, Issue 3, 2004, Pages 187-195

  Van Oort, Erica ^a   Lerouge, Patrice ^b   De Heer, Pleuni G ^a   Séveno, Martial ^b   Coquet, Laurent ^b   Modderman, Piet W ^a   Faye, Loic ^b   Aalberse, Rob C ^a   Van Ree, Ronald ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITÉ DE ROUEN   (France)

^c SANQUIN RESEARCH   (Netherlands)

Author keywords

Cross reactivity; Mannose; O and N linked glycans; Pichia pastoris; Recombinant proteins

Indexed keywords

EPITOPE; FUNGAL PROTEIN; GLYCAN DERIVATIVE; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN G ANTIBODY; MANNOSE; MYELOBLASTIN; POLLEN ANTIGEN; RECOMBINANT PROTEIN;

ANTIGEN RECOGNITION; ARTICLE; BRONCHOPULMONARY ASPERGILLOMA; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; GRASS POLLEN; HUMAN; IMMUNOASSAY; IMMUNOREACTIVITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NORMAL HUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; RADIOALLERGOSORBENT TEST;

ALLERGENS; AMINO ACID SEQUENCE; ANTIGENS, DERMATOPHAGOIDES; ASPERGILLOSIS, ALLERGIC BRONCHOPULMONARY; AUTOANTIGENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PICHIA; POLYSACCHARIDES; RADIOALLERGOSORBENT TEST; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; WEGENER GRANULOMATOSIS;

EID: 10844259780     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000081303     Document Type: Article

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