Hormesis and adaptive cellular control systems

Dose-Response

Volumn 6, Issue 2, 2008, Pages 196-208

  Zhang, Qiang ^a   Pi, Jingbo ^a   Woods, Courtney G ^a,b   Jarabek, Annie M ^c   Clewell, Harvey J ^a   Andersen, Melvin E ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b EXXONMOBIL UPSTREAM RESEARCH COMPANY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Adaptive response; Chlorine; Homeostasis; Hormesis; Oxidative stress

Indexed keywords

EID: 67349239954     PISSN: None     EISSN: 15593258     Source Type: Journal    
DOI: 10.2203/dose-response.07-028.Zhang     Document Type: Article

References (37)

1. Andersen ME and RB Conolly 1998. Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: An example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Hum Exp Toxicol 17: 683-90; discussion 701-4, 708-718
2. Arsene F, T Tomoyasu and B Bukau 2000. The heat shock response of escherichia coli. Int J Food Microbiol 55: 3-9.
3. Barrow CS, Y Alarie, JC Warrick and MF Stock 1977. Comparison of the sensory irritation response in mice to chlorine and hydrogen chloride. Arch Environ Health 32: 68-76.
4. Bloom D, S Dhakshinamoorthy and AK Jaiswal 2002. Site-directed mutagenesis of cysteine to serine in the DNA binding region of nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of nad(p)h:Quinone oxidoreductase1 gene. Oncogene 21: 2191-2200
5. Calabrese EJ 2001. Overcompensation stimulation: A mechanism for hormetic effects. Crit Rev Toxicol 31: 425-470
6. Calabrese EJ and LA Baldwin 2001a. The frequency of u-shaped dose responses in the toxicological literature. Toxicol Sci 62: 330-338
7. Calabrese EJ and LA Baldwin 2001b. Hormesis: A generalizable and unifying hypothesis. Crit Rev Toxicol 31: 353-424.
8. Calabrese EJ, KA Bachmann, et al. 2007. Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol.
9. Conolly RB and WK Lutz 2004. Nonmonotonic dose-response relationships: Mechanistic basis, kinetic modeling, and implications for risk assessment. Toxicol Sci 77: 151-157
10. Davies JM, CV Lowry and KJ Davies 1995. Transient adaptation to oxidative stress in yeast. Arch Biochem Biophys 317: 1-6.
11. Evans RB 2005. Chlorine: State of the art. Lung 183: 151-167
12. Fleisch JH, HM Maling and BB Brodie 1970. Beta-receptor activity in aorta; variations with age and species. Circ Res 26: 151-162
13. Huang CY and JE Ferrell, Jr. 1996. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A 93: 10078-10083
14. Huang HC, T Nguyen and CB Pickett 2002. Phosphorylation of nrf2 at ser-40 by protein kinase c regulates antioxidant response element-mediated transcription. J Biol Chem 277: 42769-42774
15. Kampinga HH 2006. Chaperones in preventing protein denaturation in living cells and protecting against cellular stress. Handb Exp Pharmacol: 1-42.
16. Kang KW, SH Choi and SG Kim 2002. Peroxynitrite activates nf-e2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: The role of nitric oxide synthase in rat glutathione s-transferase a2 induction. Nitric Oxide 7: 244-253
17. Kensler TW, N Wakabayashi and S Biswal 2006. Cell survival responses to environmental stresses via the keap1-nrf2-are pathway. Annu Rev Pharmacol Toxicol.
18. Kitano H 2004. Biological robustness. Nat Rev Genet 5: 826-837
19. Kitano M, T Ichihara, et al. 1998. Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat. Carcinogenesis 19: 1475-1480
20. Kitchin KT and JL Brown 1994. Dose-response relationship for rat liver DNA damage caused by 49 rodent carcinogens. Toxicology 88: 31-49.
21. Kobayashi A, MI Kang, Y Watai, KI Tong, T Shibata, K Uchida and M Yamamoto 2006. Oxidative and electrophilic stresses activate nrf2 through inhibition of ubiquitination activity of keap1. Mol Cell Biol 26: 221-229
22. Lehmler HJ, LW Robertson, AW Garrison and PR Kodavanti 2005. Effects of pcb 84 enantiomers on [3h]-phorbol ester binding in rat cerebellar granule cells and 45ca2+-uptake in rat cerebellum. Toxicol Lett 156: 391-400.
23. Li L, ME Andersen, S Heber and Q Zhang 2007. Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression. J Mol Endocrinol 38: 569-585
24. Motohashi H and M Yamamoto 2004. Nrf2-keap1 defines a physiologically important stress response mechanism. Trends Mol Med 10: 549-557
25. Pi J, W Qu, JM Reece, Y Kumagai and MP Waalkes 2003. Transcription factor nrf2 activation by inorganic arsenic in cultured keratinocytes: Involvement of hydrogen peroxide. Exp Cell Res 290: 234-245
26. Pi J, Y Bai, et al. 2007. Molecular mechanism of human nrf2 activation and degradation: Role of sequential phosphorylation by protein kinase ck2. Free Radic Biol Med 42: 1797-1806
27. Pi J, Q Zhang, CG Woods, V Wong, S Collins and ME Andersen 2008a. Activation of nrf2-mediated oxidative stress response in macrophages by hypochlorous acid. Toxicol Appl Pharmacol 226(3):236-243
28. Pi J, BA Diwan, Y Sun, W Qu, Y He, M Styblo, J Liu and MP Waalkes 2008b. Arsenic-induced malignant transformation of human keratinocytes: Involvement of nrf2. (Submitted).
29. Pullar JM, CC Winterbourn and MC Vissers 1999. Loss of gsh and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. Am J Physiol 277: H1505-12.
30. Schulz H 1888. Uber hefegifte. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere 42: 517-541
31. Southam CM and J Ehrlich 1943. Effects of extracts of western red-cedar heartwood on certain wooddecaying fungi in culture. Phytopathology 33: 517-524
32. Stebbing AR 1998. A theory for growth hormesis. Mutat Res 403: 249-258
33. Winterbourn CC and SO Brennan 1997. Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid. Biochem J 326 ( Pt 1): 87-92.
34. Woods CG, Q Zhang, RS Thomas, F Boellmann, J Wang, RC Wolf, ME Andersen and J Pi 2008. Regulatory mechanism of nrf2 activation by hypochlorous acid and concomitant activation of cellular inflammatory pathways. Society of Toxicology Annual Meeting, Seattle, Washington. Abstract #2026.
35. Xiao GG, M Wang, N Li, JA Loo and AE Nel 2003. Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line. J Biol Chem 278: 50781-50790
36. Yu R, C Chen, YY Mo, V Hebbar, ED Owuor, TH Tan and AN Kong 2000. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a nrf2-dependent mechanism. J Biol Chem 275: 39907-39913
37. Zhang Q and ME Andersen 2007. Dose response relationship in anti-stress gene regulatory networks. PLoS Comput Biol 3: e24.