Cytosolic Ca2+ movements of endothelial cells exposed to reactive oxygen intermediates: Role of hydroxyl radical-mediated redox alteration of cell-membrane Ca2+ channels

British Journal of Pharmacology

Volumn 126, Issue 6, 1999, Pages 1462-1470

  Az Ma, Toshiharu ^a,b   Saeki, Noboru ^a   Yuge, Osafumi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b ATOMIC BOMB SURVIVORS HOSPITAL   (Japan)

Author keywords

Anion channel; Calcium channel; Cytotoxicity; Endothelial cells; Haber Weiss cycle; Hydrogen peroxide; Hydroxyl radical; Intracellular calcium concentration; Superoxide anion; Xanthine oxidase

Indexed keywords

1,10 PHENANTHROLINE; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ANION CHANNEL; CALCIUM CHANNEL; CALCIUM ION; CATALASE; DEFEROXAMINE; DITHIOTHREITOL; GLUTATHIONE; HYDROXYL RADICAL; NICKEL; REACTIVE OXYGEN METABOLITE; XANTHINE; XANTHINE OXIDASE; 1,10-PHENANTHROLINE; 5,5-DIMETHYL-1-PYRROLINE-1-OXIDE; AMINE OXIDE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; HYDROGEN PEROXIDE; IRON CHELATING AGENT; OXIDIZING AGENT; PHENANTHROLINE DERIVATIVE; SCAVENGER;

ANIMAL CELL; AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SWINE; VASCULAR ENDOTHELIUM; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL RESPIRATION; CHEMISTRY; CYTOLOGY; CYTOSOL; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; AORTA; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELL MEMBRANE; CELL RESPIRATION; CELLS, CULTURED; CYCLIC N-OXIDES; CYTOSOL; DITHIOTHREITOL; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON CHELATING AGENTS; NICKEL; OXIDANTS; OXIDATION-REDUCTION; PHENANTHROLINES; REACTIVE OXYGEN SPECIES; SWINE; XANTHINE; XANTHINE OXIDASE;

EID: 0032589047     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702438     Document Type: Article

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