GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells

Biochemical Pharmacology

Volumn 74, Issue 7, 2007, Pages 1039-1049

  Taylor, Emma L ^a   Li, John T ^b   Tupper, Joan C ^c   Rossi, Adriano G ^d   Winn, Robert K ^c   Harlan, John M ^c  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Apoptosis; Bcl 2; Caspase; Myeloid; p53; Peroxynitrite

Indexed keywords

3 (3,4 DICHLOROPHENYL) 1,2,3,4 OXATRIAZOLE 5 IMINE; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXYNITRITE; PROTEIN BCL 2; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL MEMBRANE POTENTIAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSFECTION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; CASPASES; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; MICE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE DONORS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34548134863     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.06.028     Document Type: Article

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