Development of pH-responsive chitosan/heparin nanoparticles for stomach-specific anti-Helicobacter pylori therapy

Biomaterials

Volumn 30, Issue 19, 2009, Pages 3332-3342

  Lin, Yu Hsin ^a   Chang, Chiung Hung ^a   Wu, Yu Shiun ^a   Hsu, Yuan Man ^a   Chiou, Shu Fen ^a   Chen, Yi Jen ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Chitosan; Helicobacter pylori; Heparin; Intercellular spaces; Peptic ulcers

Indexed keywords

CELL-CELL JUNCTIONS; CHITOSAN SOLUTIONS; GASTRIC ACIDS; GASTRIC MUCOSAS; GASTRIC MUCOUS; HELICOBACTER PYLORI; HEPARIN; HEPARIN SOLUTIONS; INTERCELLULAR SPACES; MAGNETIC STIRRINGS; PEPTIC ULCERS; PH-RESPONSIVE; POSITIVE SURFACE CHARGES; ROOM TEMPERATURES; UREASE ENZYMES;

ACIDS; CELL MEMBRANES; CHITIN; CHITOSAN; HYDROCHLORIC ACID; POLYSACCHARIDES;

NANOPARTICLES;

CHITOSAN; HEPARIN; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL JUNCTION; DRUG DETERMINATION; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INTERCELLULAR SPACE; MAGNETISM; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; ROOM TEMPERATURE; STOMACH; STOMACH ACID; STOMACH PH; SURFACE PROPERTY;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; CHITOSAN; COCULTURE TECHNIQUES; FLUORESCENT DYES; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HEPARIN; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MATERIALS TESTING; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; NANOPARTICLES;

HELICOBACTER PYLORI;

EID: 67349204005     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.02.036     Document Type: Article

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