Miogadial and miogatrial with α,β-unsaturated 1,4-dialdehyde moieties-Novel and potent TRPA1 agonists

Life Sciences

Volumn 85, Issue 1-2, 2009, Pages 60-69

  Iwasaki, Yusaku ^a   Tanabe, Manabu ^a   Kayama, Yuko ^a   Abe, Masako ^b   Kashio, Makiko ^e   Koizumi, Kanako ^a   Okumura, Yukiko ^a   Morimitsu, Yasujiro ^c   Tominaga, Makoto ^d,e   Ozawa, Yoshio ^b   Watanabe, Tatsuo ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c OCHANOMIZU UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^e GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

HC 030031; Miogadial; Miogatrial; Polygodial; TRPA1; TRPV1

Indexed keywords

ALDEHYDE DERIVATIVE; ALLYL ISOTHIOCYANATE; CALCIUM ION; MIOGADIAL; MIOGATRIAL; POLYGODIAL; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN HEK293; CHO CELL; CONTROLLED STUDY; DRUG ACTIVATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MALE; MAMMAL CELL; MOUSE; NONHUMAN; PATCH CLAMP; SENSORY NERVE CELL;

ALDEHYDES; ANIMALS; BEHAVIOR, ANIMAL; CALCIUM; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DITERPENES; ELECTROPHYSIOLOGY; GANGLIA, SPINAL; HUMANS; MALE; MICE; MICE, INBRED C57BL; PAIN; SENSORY RECEPTOR CELLS; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPV CATION CHANNELS;

FUNGI; HEXAPODA; MAMMALIA;

EID: 67349176347     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.04.017     Document Type: Article

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