메뉴 건너뛰기




Volumn 34, Issue 8, 2009, Pages 1451-1463

Activation of NMDA receptor is associated with up-regulation of COX-2 expression in the spinal dorsal horn during nociceptive inputs in rats

Author keywords

Cyclooxygenases 2 (COX 2); Formalin test; NMDA; NMDA receptor; Rat; Spinal cord

Indexed keywords

CYCLOOXYGENASE 2; DIZOCILPINE; FORMALDEHYDE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 67349176185     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-9932-9     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 34848861063 scopus 로고    scopus 로고
    • Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception
    • 10.1016/j.pain.2007.01.015
    • DK Ahn HS Choi SP Yeo YW Woo MK Lee GY Yang HJ Jeon JS Park SS Mokha 2007 Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception Pain 132 23 32 10.1016/j.pain.2007.01.015
    • (2007) Pain , vol.132 , pp. 23-32
    • Ahn, D.K.1    Choi, H.S.2    Yeo, S.P.3    Woo, Y.W.4    Lee, M.K.5    Yang, G.Y.6    Jeon, H.J.7    Park, J.S.8    Mokha, S.S.9
  • 2
    • 0032439786 scopus 로고    scopus 로고
    • Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis
    • 10.1007/s000110050362
    • F Beiche K Brune G Geisslinger M Goppelt-Struebe 1998 Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis Inflamm Res 47 482 487 10.1007/s000110050362
    • (1998) Inflamm Res , vol.47 , pp. 482-487
    • Beiche, F.1    Brune, K.2    Geisslinger, G.3    Goppelt-Struebe, M.4
  • 3
    • 39749167838 scopus 로고    scopus 로고
    • The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: An isobolographic study
    • DOI 10.1213/ane.0b013e318163f71b, PII 0000053920080300000045
    • AS Bhat SK Tandan D Kumar V Krishna VR Prakash 2008 The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study Anesth Analg 106 978 984 (Pubitemid 351301426)
    • (2008) Anesthesia and Analgesia , vol.106 , Issue.3 , pp. 978-984
    • Bhat, A.-S.1    Kumar Tandan, S.2    Kumar, D.3    Krishna, V.4    Prakash, V.R.5
  • 4
    • 39749144481 scopus 로고    scopus 로고
    • Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model
    • 10.1017/S1740925X07000695
    • C Cavaliere G Cirillo M Rosaria Bianco F Rossi V De Novellis S Maione M Papa 2007 Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model Neuron Glia Biol 3 141 153 10.1017/S1740925X07000695
    • (2007) Neuron Glia Biol , vol.3 , pp. 141-153
    • Cavaliere, C.1    Cirillo, G.2    Rosaria Bianco, M.3    Rossi, F.4    De Novellis, V.5    Maione, S.6    Papa, M.7
  • 5
    • 26444564805 scopus 로고    scopus 로고
    • Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA
    • 10.1002/jcb.20568
    • YW Chang K Putzer L Ren B Kaboord TW Chance MW Qoronfleh R Jakobi 2005 Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA J Cell Biochem 96 314 329 10.1002/jcb.20568
    • (2005) J Cell Biochem , vol.96 , pp. 314-329
    • Chang, Y.W.1    Putzer, K.2    Ren, L.3    Kaboord, B.4    Chance, T.W.5    Qoronfleh, M.W.6    Jakobi, R.7
  • 6
    • 46449133788 scopus 로고    scopus 로고
    • Intraprostatic botulinum toxin a injection inhibits cyclooxygenase-2 expression and suppresses prostatic pain on capsaicin induced prostatitis model in rat
    • 10.1016/j.juro.2007.07.120
    • YC Chuang N Yoshimura CC Huang M Wu PH Chiang MB Chancellor 2008 Intraprostatic botulinum toxin a injection inhibits cyclooxygenase-2 expression and suppresses prostatic pain on capsaicin induced prostatitis model in rat J Urol 180 742 748 10.1016/j.juro.2007.07.120
    • (2008) J Urol , vol.180 , pp. 742-748
    • Chuang, Y.C.1    Yoshimura, N.2    Huang, C.C.3    Wu, M.4    Chiang, P.H.5    Chancellor, M.B.6
  • 7
    • 0033037253 scopus 로고    scopus 로고
    • In vitro prostanoid release from spinal cord following peripheral inflammation: Effects of substance P, NMDA and capsaicin
    • DM Dirig TL Yaksh 1999 In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin Br J Pharmacol 126 1333 1340 10.1038/sj.bjp.0702427 (Pubitemid 29142063)
    • (1999) British Journal of Pharmacology , vol.126 , Issue.6 , pp. 1333-1340
    • Dirig, D.M.1    Yaksh, T.L.2
  • 8
    • 0017643233 scopus 로고
    • The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats
    • 10.1016/0304-3959(77)90130-0
    • D Dubuisson SG Dennis 1977 The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats Pain 4 161 174 10.1016/0304-3959(77)90130-0
    • (1977) Pain , vol.4 , pp. 161-174
    • Dubuisson, D.1    Dennis, S.G.2
  • 10
    • 0035140399 scopus 로고    scopus 로고
    • Long-lasting inflammation and long-term hyperalgesia after subcutaneous formalin injection into the rat hindpaw
    • 10.1054/jpai.2001.9804
    • KY Fu AR Light W Maixner 2001 Long-lasting inflammation and long-term hyperalgesia after subcutaneous formalin injection into the rat hindpaw J Pain 2 2 11 10.1054/jpai.2001.9804
    • (2001) J Pain , vol.2 , pp. 2-11
    • Fu, K.Y.1    Light, A.R.2    Maixner, W.3
  • 11
    • 1642293993 scopus 로고    scopus 로고
    • Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia
    • 10.1523/JNEUROSCI.5054-03.2004
    • JR Ghilardi CI Svensson SD Rogers TL Yaksh PW Mantyh 2004 Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia J Neurosci 24 2727 2732 10.1523/JNEUROSCI.5054-03.2004
    • (2004) J Neurosci , vol.24 , pp. 2727-2732
    • Ghilardi, J.R.1    Svensson, C.I.2    Rogers, S.D.3    Yaksh, T.L.4    Mantyh, P.W.5
  • 12
    • 39749168335 scopus 로고    scopus 로고
    • Effect of endotoxin treatment on the expression and localization of spinal cyclooxygenase, prostaglandin synthases, and PGD2 receptors
    • 10.1111/j.1471-4159.2007.05078.x
    • M Grill A Heinemann G Hoefler BA Peskar R Schuligoi 2008 Effect of endotoxin treatment on the expression and localization of spinal cyclooxygenase, prostaglandin synthases, and PGD2 receptors J Neurochem 104 1345 1357 10.1111/j.1471-4159.2007.05078.x
    • (2008) J Neurochem , vol.104 , pp. 1345-1357
    • Grill, M.1    Heinemann, A.2    Hoefler, G.3    Peskar, B.A.4    Schuligoi, R.5
  • 13
    • 41649118003 scopus 로고    scopus 로고
    • 2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NF-kappaB activity
    • 10.1038/bjp.2008.33
    • 2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NF-kappaB activity Br J Pharmacol 153 1538 1549 10.1038/bjp.2008.33
    • (2008) Br J Pharmacol , vol.153 , pp. 1538-1549
    • Hu, S.S.1    Bradshaw, H.B.2    Chen, J.S.3    Tan, B.4    Walker, J.M.5
  • 14
    • 39749201671 scopus 로고    scopus 로고
    • The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity
    • DOI 10.1213/ane.0b013e318163f602, PII 0000053920080300000044
    • IO Lee Y Seo 2008 The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity Anesth Analg 106 972 977 (Pubitemid 351301425)
    • (2008) Anesthesia and Analgesia , vol.106 , Issue.3 , pp. 972-977
    • Lee, I.O.1    Seo, Y.2
  • 15
    • 8844274306 scopus 로고    scopus 로고
    • Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression
    • DY Leger B Liagre C Corbière J Cook-Moreau JL Beneytout 2004 Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression Int J Oncol 25 3 555 562
    • (2004) Int J Oncol , vol.25 , Issue.3 , pp. 555-562
    • Leger, D.Y.1    Liagre, B.2    Corbière, C.3    Cook-Moreau, J.4    Beneytout, J.L.5
  • 16
    • 3142757183 scopus 로고    scopus 로고
    • MK-801 inhibits formalin-induced cyclooxygenase-2 expression in the dorsal horn of the spinal cord in rats
    • SQ Li WB Li XC Sun QJ Li XL Chen J Ai 2004 MK-801 inhibits formalin-induced cyclooxygenase-2 expression in the dorsal horn of the spinal cord in rats Sheng Li Xue Bao 56 66 72
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 66-72
    • Li, S.Q.1    Li, W.B.2    Sun, X.C.3    Li, Q.J.4    Chen, X.L.5    Ai, J.6
  • 17
    • 0034736189 scopus 로고    scopus 로고
    • Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord
    • 10.1016/S0306-4522(00)00361-4
    • C Maihöfner I Tegeder C Euchenhofer D de Witt K Brune R Bang W Neuhuber G Geisslinger 2000 Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord Neuroscience 101 1093 1108 10.1016/S0306-4522(00)00361-4
    • (2000) Neuroscience , vol.101 , pp. 1093-1108
    • Maihöfner, C.1    Tegeder, I.2    Euchenhofer, C.3    De Witt, D.4    Brune, K.5    Bang, R.6    Neuhuber, W.7    Geisslinger, G.8
  • 18
    • 0030821492 scopus 로고    scopus 로고
    • The inhibition of nitric oxide-activated poly(ADP-ribose) synthetase attenuates transsynaptic alteration of spinal cord dorsal horn neurons and neuropathic pain in the rat
    • 10.1016/S0304-3959(97)00063-8
    • J Mao DD Price J Zhu J Lu DJ Mayer 1997 The inhibition of nitric oxide-activated poly(ADP-ribose) synthetase attenuates transsynaptic alteration of spinal cord dorsal horn neurons and neuropathic pain in the rat Pain 72 355 366 10.1016/S0304-3959(97)00063-8
    • (1997) Pain , vol.72 , pp. 355-366
    • Mao, J.1    Price, D.D.2    Zhu, J.3    Lu, J.4    Mayer, D.J.5
  • 19
    • 34247568933 scopus 로고    scopus 로고
    • Constitutive cyclooxygenase-2 is involved in central nociceptive processes in humans
    • 10.1097/01.anes.0000265162.39932.33
    • F Martin D Fletcher M Chauvin D Bouhassira 2007 Constitutive cyclooxygenase-2 is involved in central nociceptive processes in humans Anesthesiology 106 1013 1018 10.1097/01.anes.0000265162.39932.33
    • (2007) Anesthesiology , vol.106 , pp. 1013-1018
    • Martin, F.1    Fletcher, D.2    Chauvin, M.3    Bouhassira, D.4
  • 20
    • 0028558934 scopus 로고
    • A method to perform direct transcutaneous intrathecal injection in rats
    • 10.1016/1056-8719(94)90087-6
    • C Mestre T Pélissier J Fialip G Wilcox A Eschalier 1994 A method to perform direct transcutaneous intrathecal injection in rats J Pharmacol Toxicol Methods 32 197 200 10.1016/1056-8719(94)90087-6
    • (1994) J Pharmacol Toxicol Methods , vol.32 , pp. 197-200
    • Mestre, C.1    Pélissier, T.2    Fialip, J.3    Wilcox, G.4    Eschalier, A.5
  • 21
    • 13144258841 scopus 로고    scopus 로고
    • Spinal prostaglandin formation and pain perception following thoracotomy: A role for cyclooxygenase-2
    • 10.1378/chest.125.4.1321
    • C McCrory D Fitzgerald 2004 Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2 Chest 125 1321 1327 10.1378/chest.125.4.1321
    • (2004) Chest , vol.125 , pp. 1321-1327
    • McCrory, C.1    Fitzgerald, D.2
  • 22
    • 40849130883 scopus 로고    scopus 로고
    • Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice
    • 10.1016/j.neuroscience.2007.10.039
    • M Narita M Shimamura S Imai C Kubota Y Yajima T Takagi M Shiokawa T Inoue M Suzuki T Suzuki 2008 Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice Neuroscience 152 477 486 10.1016/j.neuroscience.2007.10.039
    • (2008) Neuroscience , vol.152 , pp. 477-486
    • Narita, M.1    Shimamura, M.2    Imai, S.3    Kubota, C.4    Yajima, Y.5    Takagi, T.6    Shiokawa, M.7    Inoue, T.8    Suzuki, M.9    Suzuki, T.10
  • 24
    • 6944250117 scopus 로고    scopus 로고
    • Spinal neural cyclooxygenase-2 mediates pain caused in a rat model of lumbar disk herniation
    • 10.1016/j.jpain.2004.06.004
    • S Ohtori K Takahashi Y Aoki H Doya T Ozawa T Saito H Moriya 2004 Spinal neural cyclooxygenase-2 mediates pain caused in a rat model of lumbar disk herniation J Pain 5 385 391 10.1016/j.jpain.2004.06.004
    • (2004) J Pain , vol.5 , pp. 385-391
    • Ohtori, S.1    Takahashi, K.2    Aoki, Y.3    Doya, H.4    Ozawa, T.5    Saito, T.6    Moriya, H.7
  • 25
    • 0035370602 scopus 로고    scopus 로고
    • Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation
    • 10.1016/S0304-3940(01)01801-8
    • GM Pitcher JL Henry 2001 Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation Neuscience Lett 305 45 48 10.1016/S0304-3940(01)01801-8
    • (2001) Neuscience Lett , vol.305 , pp. 45-48
    • Pitcher, G.M.1    Henry, J.L.2
  • 26
  • 27
    • 49949100761 scopus 로고    scopus 로고
    • Intrathecal clonidine suppresses phosphorylation of the N-methyl-d-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain
    • DH Roh HW Kim SY Yoon HS Seo YB Kwon HJ Han AJ Beitz JH Lee 2008 Intrathecal clonidine suppresses phosphorylation of the N-methyl-d-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain Anesth Analg 107 693 700
    • (2008) Anesth Analg , vol.107 , pp. 693-700
    • Roh, D.H.1    Kim, H.W.2    Yoon, S.Y.3    Seo, H.S.4    Kwon, Y.B.5    Han, H.J.6    Beitz, A.J.7    Lee, J.H.8
  • 28
    • 0035932121 scopus 로고    scopus 로고
    • Interleukin-1beta-mediated induction of COX-2 in the CNS contributes to inflammatory pain hypersensitivity
    • 10.1038/35068566
    • TA Samad KA Moore A Sapirstein S Billet A Allchorne S Poole JV Bonventre CJ Woolf 2001 Interleukin-1beta-mediated induction of COX-2 in the CNS contributes to inflammatory pain hypersensitivity Nature 410 471 475 10.1038/35068566
    • (2001) Nature , vol.410 , pp. 471-475
    • Samad, T.A.1    Moore, K.A.2    Sapirstein, A.3    Billet, S.4    Allchorne, A.5    Poole, S.6    Bonventre, J.V.7    Woolf, C.J.8
  • 29
    • 52149094547 scopus 로고    scopus 로고
    • P38 MAPK mediates COX-2 gene expression by corticosterone in cardiomyocytes
    • 10.1016/j.cellsig.2008.07.003
    • H Sun B Xu H Inoue QM Chen 2008 P38 MAPK mediates COX-2 gene expression by corticosterone in cardiomyocytes Cell Signal 20 11 1952 1959 10.1016/j.cellsig.2008.07.003
    • (2008) Cell Signal , vol.20 , Issue.11 , pp. 1952-1959
    • Sun, H.1    Xu, B.2    Inoue, H.3    Chen, Q.M.4
  • 31
    • 0036172409 scopus 로고    scopus 로고
    • The spinal phospholipase-cyclooxygenase-prostanoid cascade in nociceptive processing
    • 10.1146/annurev.pharmtox.42.092401.143905
    • CI Svensson TL Yaksh 2002 The spinal phospholipase-cyclooxygenase- prostanoid cascade in nociceptive processing Annu Rev Pharmacol Toxicol 42 553 583 10.1146/annurev.pharmtox.42.092401.143905
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 553-583
    • Svensson, C.I.1    Yaksh, T.L.2
  • 32
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
    • 10.1046/j.1471-4159.2001.00054.x
    • JD Sweatt 2001 The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory J Neurochem 76 1 10 10.1046/j.1471-4159.2001.00054.x
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 33
    • 0028233550 scopus 로고
    • Extra-territorial pain in rats with a peripheral mononeuropathy: Mechano-hyperalgesia and mechano-allodynia in the territory of an uninjured nerve
    • 10.1016/0304-3959(94)90013-2
    • M Tal GJ Bennett 1994 Extra-territorial pain in rats with a peripheral mononeuropathy: mechano-hyperalgesia and mechano-allodynia in the territory of an uninjured nerve Pain 57 375 382 10.1016/0304-3959(94)90013-2
    • (1994) Pain , vol.57 , pp. 375-382
    • Tal, M.1    Bennett, G.J.2
  • 34
    • 0035177677 scopus 로고    scopus 로고
    • Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord
    • 10.1046/j.1471-4159.2001.00613.x
    • I Tegeder E Niederberger G Vetter L Bräutigam G Geisslinger 2001 Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord J Neurochem 79 777 786 10.1046/j.1471-4159.2001.00613.x
    • (2001) J Neurochem , vol.79 , pp. 777-786
    • Tegeder, I.1    Niederberger, E.2    Vetter, G.3    Bräutigam, L.4    Geisslinger, G.5
  • 36
    • 0035056034 scopus 로고    scopus 로고
    • 2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation
    • 10.1016/S0304-3959(01)00258-5
    • 2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation Pain 92 213 218 10.1016/S0304-3959(01)00258-5
    • (2001) Pain , vol.92 , pp. 213-218
    • Vetter, G.1    Geisslinger, G.2    Tegeder, I.3
  • 37
    • 67249089972 scopus 로고    scopus 로고
    • Antinociceptive action of GLYX-13: An N-methyl-d-aspartate receptor glycine site partial agonist
    • 10.1097/WNR.0b013e32830435c9
    • PL Wood SA Mahmood JR Moskal 2008 Antinociceptive action of GLYX-13: an N-methyl-d-aspartate receptor glycine site partial agonist NeuroReport 19 1059 1061 10.1097/WNR.0b013e32830435c9
    • (2008) NeuroReport , vol.19 , pp. 1059-1061
    • Wood, P.L.1    Mahmood, S.A.2    Moskal, J.R.3
  • 38
    • 0036201503 scopus 로고    scopus 로고
    • The role of cyclooxygenase-1 and -2 in the rat formalin test
    • T Yamamoto N Nozaki-Taguchi 2002 The role of cyclooxygenase-1 and -2 in the rat formalin test Anesth Analg 94 962 967 10.1097/00000539-200204000-00035 (Pubitemid 34263748)
    • (2002) Anesthesia and Analgesia , vol.94 , Issue.4 , pp. 962-967
    • Yamamoto, T.1    Nozaki-Taguchi, N.2
  • 39
    • 0032444328 scopus 로고    scopus 로고
    • COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA
    • T Yamamoto Y Sakashita 1998 COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA NeuroReport 9 3869 3873 (Pubitemid 29189318)
    • (1998) NeuroReport , vol.9 , Issue.17 , pp. 3869-3873
    • Yamamoto, T.1    Sakashita, Y.2
  • 41
    • 0033529223 scopus 로고    scopus 로고
    • The spinal biology in humans and animals of pain states generated by persistent small afferent input
    • 10.1073/pnas.96.14.7680
    • TL Yaksh XY Hua I Kalcheva N Nozaki-Taguchi M Marsala 1999 The spinal biology in humans and animals of pain states generated by persistent small afferent input Proc Natl Acad Sci USA 96 14 7680 7686 10.1073/pnas.96.14.7680
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.14 , pp. 7680-7686
    • Yaksh, T.L.1    Hua, X.Y.2    Kalcheva, I.3    Nozaki-Taguchi, N.4    Marsala, M.5
  • 42
    • 0037087179 scopus 로고    scopus 로고
    • Antisense oligonucleotides to N-methyl-d-aspertate receptor subunits attenuate formalin-induced nociception in the rat
    • 10.1016/S0006-8993(02)02243-6
    • R Yukhananov J Guan G Crosby 2002 Antisense oligonucleotides to N-methyl-d-aspertate receptor subunits attenuate formalin-induced nociception in the rat Brain Res 930 163 169 10.1016/S0006-8993(02)02243-6
    • (2002) Brain Res , vol.930 , pp. 163-169
    • Yukhananov, R.1    Guan, J.2    Crosby, G.3
  • 43
    • 48849111049 scopus 로고    scopus 로고
    • Enhancement of spinal N-methyl-d-aspartate receptor function by remifentanil action at delta-opioid receptors as a mechanism for acute opioid-induced hyperalgesia or tolerance
    • M Zhao DT Joo 2008 Enhancement of spinal N-methyl-d-aspartate receptor function by remifentanil action at delta-opioid receptors as a mechanism for acute opioid-induced hyperalgesia or tolerance Anesthesiology 109 308 317
    • (2008) Anesthesiology , vol.109 , pp. 308-317
    • Zhao, M.1    Joo, D.T.2
  • 44
    • 33846839548 scopus 로고    scopus 로고
    • GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury
    • 10.1016/j.pain.2006.08.032
    • FY Zhao D Spanswick JC Martindale AJ Reeve IP Chessell 2007 GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury Pain 128 78 87 10.1016/j.pain.2006.08.032
    • (2007) Pain , vol.128 , pp. 78-87
    • Zhao, F.Y.1    Spanswick, D.2    Martindale, J.C.3    Reeve, A.J.4    Chessell, I.P.5
  • 45
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • 10.1016/0304-3959(83)90201-4
    • M Zimmermann 1983 Ethical guidelines for investigations of experimental pain in conscious animals Pain 16 109 110 10.1016/0304-3959(83)90201-4
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.