Novel residues lining the CFTR Chloride channel pore identified by functional modification of introduced cysteines

Journal of Membrane Biology

Volumn 228, Issue 3, 2009, Pages 151-164

  Fatehi, Mohammad ^a,b   Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

Chloride channel; Cystic fibrosis transmembrane conductance regulator; Ion channel pore; Permeation; Selectivity; Single channel; Site directed mutagenesis; Substituted cysteine accessibility

Indexed keywords

AMINO ACID; ANION; CHLORIDE CHANNEL; CYSTEINE; ION CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; GENETIC TRANSFECTION; MEMBRANE CONDUCTANCE; MOUTH; MUTAGENESIS; NONHUMAN; PATCH CLAMP;

AMINO ACID SEQUENCE; ANIMALS; CRICETINAE; CYSTEINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MESYLATES; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; SULFHYDRYL REAGENTS;

EID: 67349171421     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-009-9167-3     Document Type: Article

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