Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore

Molecular Pharmacology

Volumn 71, Issue 5, 2007, Pages 1360-1368

  St Aubin, Chantal N ^a,b   Zhou, Jing Jun ^a   Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CHLORIDE CHANNEL; GLIBENCLAMIDE; LONIDAMINE; LYSINE; SURAMIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRANSMEMBRANE CONDUCTANCE REGULATOR CHLORIDE CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; CYTOPLASM; DRUG RECEPTOR BINDING; ELECTRICITY; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SITE DIRECTED MUTAGENESIS;

ANIMALS; ARGININE; BINDING SITES; CHLORIDES; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOPLASM; MEMBRANE TRANSPORT MODULATORS; MODELS, BIOLOGICAL; MUTANT PROTEINS; SURAMIN;

EID: 34247493249     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.031732     Document Type: Article

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