Expression of cytochrome P450 and transcription factors during in vitro differentiation of mouse embryonic stem cells into hepatocytes

Drug Metabolism and Pharmacokinetics

Volumn 23, Issue 3, 2008, Pages 188-195

  Maezawa, Kayoko ^a   Miyazato, Kenji ^a   Matsunaga, Tamihide ^a   Momose, Yasuyuki ^a   Imamura, Tetsuya ^b   Johkura, Kohei ^b   Sasaki, Katsunori ^b   Ohmori, Shigeru ^a  

^a SHINSHU UNIVERSITY HOSPITAL   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Albumin; Alpha fetoprotein; Cyp3a; Cytochrome P450; Differentiation; Embryoid body; Embryonic stem cell; Hepatocyte; Mouse; Transcription factor

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; ALBUMIN; ALPHA FETOPROTEIN; AROMATIC HYDROCARBON RECEPTOR; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 2C; CYTOCHROME P450 2C29; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; CYTOCHROME P450 7B; CYTOCHROME P450 7B1; GLUCOCORTICOID RECEPTOR; GLUCOSE 6 PHOSPHATE; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; ONCOSTATIN M; PREGNANE X RECEPTOR; SCATTER FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYONIC STEM CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LIVER CELL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; ANIMAL; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYONIC STEM CELLS; GENE EXPRESSION; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; MICE; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 48849090855     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.23.188     Document Type: Article

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