The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major

Molecular and Biochemical Parasitology

Volumn 166, Issue 2, 2009, Pages 142-152

  Vickers, Tim J ^a   Murta, Silvane M F ^a   Mandell, Michael A ^a   Beverley, Stephen M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Formyl tetrahydrofolate ligase; Formyl methionyl tRNAMet; Glycine; Methylene tetrahydrofolate cyclohydrolase dehydrogenase; Serine; Virulence

Indexed keywords

FOLIC ACID; FORMATE TETRAHYDROFOLATE LIGASE; GREEN FLUORESCENT PROTEIN; METHYLENETETRAHYDROFOLATE DEHYDROGENASE; PTERIDINE; TRANSFER RNA METHYLTRANSFERASE;

ARTICLE; AUXOTROPHY; BIOSYNTHESIS; CELL FRACTIONATION; CYTOSOL; ENZYME ANALYSIS; FOLATE METABOLISM; INFECTION; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIA MEXICANA; METABOLITE; MICROBIAL GROWTH; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TRYPANOSOMA; TRYPANOSOMA BRUCEI; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; BIOSYNTHETIC PATHWAYS; CYTOSOL; KINETICS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LEUCOVORIN; MICE; MICE, INBRED BALB C; MITOCHONDRIA; PHYLOGENY; PROTOZOAN PROTEINS;

ANIMALIA; LEISHMANIA MAJOR; PROTOZOA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 67349156399     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.03.009     Document Type: Article

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