A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of Chinese hamster cells

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33829-33836

  McCarthy, Erin A ^a   Titus, Steven A ^b   Taylor, Shirley M ^a,b   Jackson Cook, Colleen ^a,b   Moran, Richard G ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL MEMBRANES; DNA; FLUORESCENCE; GENES; GROWTH KINETICS; MUTAGENESIS; PROTEINS;

GENOMIC SEQUENCE ANALYSIS; MITOCHONDRIAL MEMBRANES;

BIOCHEMISTRY;

CARRIER PROTEIN; COMPLEMENTARY DNA; FOLIC ACID; GLUTAMIC ACID; GLYCINE; MEMBRANE PROTEIN;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AUXOTROPHY; CELL GROWTH; CELL MUTANT; CELL STRAIN GLYB; CELL SURVIVAL; CHO CELL; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC TRANSFECTION; MFT GENE; MITOCHONDRIAL MEMBRANE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TRANSPORT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; WILD TYPE;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL SURVIVAL; CHO CELLS; CODON; CRICETINAE; DNA, COMPLEMENTARY; FOLIC ACID; GENE EXPRESSION; GLUTAMIC ACID; GLYCINE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; POINT MUTATION; SEQUENCE HOMOLOGY; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 4043146497     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403677200     Document Type: Article

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