Interaction of mitochondrial initiation factor 2 with mitochondrial fMet-tRNA

Nucleic Acids Research

Volumn 32, Issue 18, 2004, Pages 5464-5470

  Spencer, Angela C ^a   Spremulli, Linda L ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2; METHIONINE TRANSFER RNA; MITOCHONDRIAL PROTEIN; IFM1 PROTEIN, S CEREVISIAE; INITIATION FACTOR; METHIONYL TRNA FORMYLTRANSFERASE; METHIONYL-TRNA FORMYLTRANSFERASE; RNA; RNA, MITOCHONDRIAL; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSFERASE; TRNA, FORMYLMETHIONINE; TRNA, FORMYLMETHIONINE-;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATTLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; IN VITRO STUDY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RIBOSOME; ANIMAL; BIOSYNTHESIS; METABOLISM; RNA TRANSLATION;

BOVINAE; MAMMALIA;

ANIMALS; CATTLE; EUKARYOTIC INITIATION FACTORS; HYDROXYMETHYL AND FORMYL TRANSFERASES; MITOCHONDRIAL PROTEINS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; RIBOSOMES; RNA; RNA, TRANSFER, MET; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 6044234880     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh886     Document Type: Article

References (32)

1. Watanabe,K. and Osawa,S. (1995) tRNA sequences and variations of the genetic code. In Soll,D. and RajBhandary,U. (eds), tRNA: Structure, Biosynthesis and Function. American Society for Microbiology, Washington, DC, pp. 225-250.
2. Takemoto,C., Ueda,T., Miura,K. and Watanabe,K. (1999) Nucleotide sequences of animal mitochondrial tRNAs(Met) possibly recognizing both AUG and AUA codons. Nucleic Acids Symp. Ser., 42, 77-78.
3. Met to decode AUG and AUA codons. Biochimie, 77, 104-108.
4. f. J. Biol. Chem., 252, 2519-2523.
5. Takeuchi,N., Ueda,T. and Watanabe,K. (1998) Expression and characterization of bovine mitochondrial methionyl-tRNA transformylase. J. Biochem., 124, 1069-1071.
6. Takeuchi,N., Kawakami,M., Omori,A., Ueda,T., Spremulli,L.L. and Watanabe,K. (1998) Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver: purification, characterization and gene structure. J. Biol. Chem., 273, 15085-15090.
7. Takeuchi,N., Vial,L., Panvert,M., Schmitt,E., Watanabe,K., Mechulam,Y. and Blanquet,S. (2001) Recognition of tRNAs by methionyl-tRNA transformylase from mammalian mitochondria. J. Biol. Chem., 276, 20064-20068.
8. Liao,H.-X. and Spremulli,L.L. (1991) Initiation of protein synthesis in animal mitochondria: purification and characterization of translational initiation factor 2. J. Biol. Chem., 266, 20714-20719.
9. Woriax,V., Spremulli,G. and Spremulli,L.L. (1996) Nucleotide and aminoacyl-tRNA specificity of the mammalian mitochondrial elongation factor EF-Tu:Ts complex. Biochim. Biophys. Acta, 1307, 66-72.
10. Li,Y., Holmes,W.B., Appling,D.R. and RajBhandary,U.L. (2000) Initiation of protein synthesis in Saccharomyces cerevisiae mitochondria without formylation of the initiator tRNA. J. Bacteriol. 182, 2886-2892.
11. Tibbetts,A.S., Oesterlin,L., Chan,S.Y., Kramer,G., Hardesty,B. and Appling,D.R. (2003) Mammalian mitochondrial initiation factor 2 supports yeast mitochondrial translation without formylated initiator tRNA. J. Biol. Chem., 278, 31774-31780.
12. Garofalo,C., Trinko,R., Kramer,G., Appling,D.R. and Hardesty,B. (2003) Purification and characterization of yeast mitochondrial initiation factor 2. Arch. Biochem. Biophys., 413, 243-252.
13. Walker,R.T. and RajBhandary,U.L. (1972) Studies on polynucleotides. CI. Escherichia coli tyrosine and formylmethionine transfer ribonucleic acids: effect of chemical modification of 4-thiouridine to uridine on their biological properties. J. Biol. Chem., 247, 4879-4892.
14. Spencer,A.C., Heck,A.H., Takeuchi,N., Watanabe,K. and Spremulli,L.L. (2004) Characterization of the human mitochondrial methionyl-tRNA synthetase. Biochemistry, 43, 9743-9754.
15. Matthews,D.E., Hessler,R.A., Denslow,N.D., Edwards,J.S. and O'Brien,T.W. (1982) Protein composition of the bovine mitochondrial ribosome. J. Biol. Chem., 257, 8788-8794.
16. Liao,H.-X. and Spremulli,L.L. (1989) Interaction of bovine mitochondrial ribosomes with messenger RNA. J. Biol. Chem., 264, 7518-7522.
17. Sambrook,J., Fritsch,E. and Maniatis,T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
18. Graves,M. and Spremulli,L.L. (1983) Activity of Euglena gracilis chloroplast ribosomes with prokaryotic and eukaryotic initiation factors. Arch. Biochem. Biophys., 222, 192-199.
19. Bullard,J.M., Cai,Y.-C., Zhang,Y. and Spremulli,L.L. (1999) Effects of domain exchanges between Escherichia coli and mammalian mitochondrial EF-Tu on interactions with guanine nucleotides, aminoacyl-tRNA and ribosomes. Biochim. Biophys. Acta, 1446, 102-114.
20. Graves,M., Breitenberger,C. and Spremulli,L.L. (1980) Euglena gracilis chloroplast ribosomes: improved isolation procedure and comparison of elongation factor specificity with prokaryotic and eukaryotic ribosomes. Arch. Biochem. Biophys., 204, 444-454.
21. fMet. Biochem. Biophys. Res. Commun., 91, 1068-1074.
22. Mortensen,K., Kildsgaard,J., Moreno,J.M.P., Steffensen,S., Egebjerg,J. and Sperling-Petersen,H. (1998) A six-domain structural model for Escherichia coli translation initiation factor 2. Characterization of twelve surface epitopes. Biochem. Biophys. Res. Commun., 46, 1027-1041.
23. Misselwitz,R., Welfle,K., Krafft,C., Welfle,H., Brandi,L., Caserta,E. and Gualerzi,C. (1999) The fMet-tRNA binding domain of translational initiation factor IF2: role and environment of its two Cys residues. FEBS Lett., 459, 332-336.
24. Szkaradkiewicz,K., Zuleeg,T., Limmer,S. and Sprinzl,M. (2000) Interaction of fMet-tRNAfMet and fMet-AMP with the C-terminal domain of Thermus thermophilus translation initiation factor 2. Eur. J. Biochem., 267, 4290-4299.
25. Spurio,R., Brandi,L., Caserta,E., Pon,C., Gualerzi,C., Misselwitz,R., Krafft,C., Welfle,K. and Welfle,H. (2000) The C-terminal subdomain (IF2 C-2) contains the entire fMet-tRNA binding site of initiation factor IF2. J. Biol. Chem., 275, 2447-2454.
26. Krafft,C., Diehl,A., Laettig,S., Behlke,J., Heinemann,U., Pon,C.L., Gualerzi,C.O. and Welfle,H. (2000) Interaction of fMet-tRNA(fMet) with the C-terminal domain of translational initiation factor IF2 from Bacillus stearothermophilus. FEBS Lett., 471, 128-132.
27. Baumstark,B.R., Spremulli,L.L., RajBhandary,U.L. and Brown,G.M. (1977) Initiation of protein synthesis without formylation in a mutant of Escherichia coli that grows in the absence of tetrahydrofolate. J. Bacteriol., 129, 457-471.
28. RajBhandary,U. and Chow,C. (1995) Initiator tRNAs and initiation of protein synthesis. In Soll,D. and RajBhandary,U. (eds), tRNA: Structure, Biosynthesis and Function. American Society for Microbiology, Washington, DC, pp. 511-528.
29. Sundari,R.M., Stringer,E.A., Schulman,L.H. and Maitra,U. (1976) Interaction of bacterial initiation factor 2 with initiator tRNA. J. Biol. Chem., 251, 3338-3345.
30. Wu,X. and RajBhandary,U. (1997) Effect of the amino acid attached to Escherichia coli initiator tRNA on its affinity for the initiation factor IF2 and on the EF2 dependence of its binding to the ribosome. J. Biol. Chem., 272, 1891-1895.
31. Meunier,S., Spurio,R., Czisch,M., Wechselberger,R., Guenneugues,M., Gualerzi,C.O. and Boelens,R. (2000) Structure of the fMet-tRNA(fMet)-binding domain of B.stearothermophilus initiation factor IF2. EMBO J., 19, 1918-1926.
32. Guenneugues,M., Caserta,E., Brandi,L., Spurio,R., Meunier,B., Pon,C.L., Boelens,R. and Gualerzi,C.O. (2000) Mapping the fMet-tRNA binding site of initiation factor IF2. EMBO J., 19, 5233-5240.