The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major

Journal of Biological Chemistry

Volumn 283, Issue 1, 2008, Pages 155-165

  Scott, David A ^a   Hickerson, Suzanne M ^a   Vickers, Tim J ^a   Beverley, Stephen M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; MAMMALS; METABOLISM; MOLECULAR BIOLOGY; PROTEINS; SYNTHESIS (CHEMICAL);

BIOINFORMATIC ANALYSIS; PARASITE METABOLISM; PROMASTIGOTES;

PATHOGENS;

GLYCINE; GLYCINE CLEAVAGE SYSTEM; GLYCINE DEHYDROGENASE (DECARBOXYLATING); METHYLENETETRAHYDROFOLIC ACID; SERINE; THYMIDINE PHOSPHATE;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; GENOME; INFECTION RESISTANCE; INFECTION SENSITIVITY; LEISHMANIA MAJOR; MACROPHAGE; METABOLISM; MITOCHONDRION; MOUSE; NONHUMAN; PARASITE DEVELOPMENT; PARASITE VIRULENCE; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRYPANOSOMA BRUCEI;

ANIMALS; GENOME, PROTOZOAN; GLYCINE DEHYDROGENASE (DECARBOXYLATING); GREEN FLUORESCENT PROTEINS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; METHOTREXATE; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MODELS, GENETIC; MUTATION; PHENOTYPE; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; TRYPANOSOMA BRUCEI BRUCEI; VIRULENCE;

LEISHMANIA MAJOR; MUS; PROTOZOA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 38049148752     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708014200     Document Type: Article

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