Analyzing the binding of Co(II)-specific inhibitors to the methionyl aminopeptidases from Escherichia coli and Pyrococcus furiosus

Journal of Biological Inorganic Chemistry

Volumn 14, Issue 4, 2009, Pages 573-585

  Mitra, Sanghamitra ^a,d   Sheppard, George ^c   Wang, Jieyi ^c   Bennett, Brian ^b   Holz, Richard C ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c ABBOTT LABORATORIES   (United States)

^d Boston University   (United States)

Author keywords

Antibiotics; Electron paramagnetic resonance; Electronic absorption; Hydrolysis; Manganese

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTIINFECTIVE AGENT; BESTATIN; COBALT; METHIONYL AMINOPEPTIDASE; POLYPEPTIDE; PROTEINASE; TRIAZOLE;

ARTICLE; ENZYME ANALYSIS; ENZYME KINETICS; ESCHERICHIA COLI; IC 50; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS;

AMINOPEPTIDASES; BINDING SITES; CATALYTIC DOMAIN; COBALT; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; LEUCINE; MANGANESE; MOLECULAR STRUCTURE; PROTEIN BINDING; PYROCOCCUS FURIOSUS; THERMODYNAMICS; TRIAZOLES;

ESCHERICHIA COLI; PYROCOCCUS FURIOSUS;

EID: 67349143658     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-009-0471-2     Document Type: Article

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