Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29

Biochemical and Biophysical Research Communications

Volumn 322, Issue 3, 2004, Pages 1012-1017

  Selvakumar, Ponniah ^a,b   Lakshmikuttyamma, Ashakumary ^a,b   Lawman, Zoe ^b   Bonham, Keith ^b   Dimmock, Jonathan R ^c   Sharma, Rajendra K ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b SASKATCHEWAN CANCER AGENCY   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Lipid modification; Methionine aminopeptidase 2; Myristoylation; N Myristoyltransferase; N Myristoyltransferase inhibitor protein; pp60 c src

Indexed keywords

METHIONYL AMINOPEPTIDASE; METHIONYL AMINOPEPTIDASE 2; PROTEIN N MYRISTOYLTRANSFERASE; PROTEIN N MYRISTOYLTRANSFERASE INHIBITOR; PROTEIN N MYRISTOYLTRANSFERASE INHIBITOR PROTEIN 71; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL DENSITY; CELL STRAIN; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; MYRISTYLATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ACYLTRANSFERASES; AMINOPEPTIDASES; CELL LINE, TUMOR; COLONIC NEOPLASMS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METALLOENDOPEPTIDASES; NEOPLASM PROTEINS;

EID: 4444311427     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.021     Document Type: Article

References (45)

1. P. Selvakumar, M.K. Pasha, L. Ashakumary, J.R. Dimmock, and R.K. Sharma Myristoyl-CoA:protein N-myristoyltransferase: a novel molecular approach for cancer therapy Int. J. Mol. Med. 10 2002 493 500
2. T.A. Farazi, G. Waksman, and J.I. Gordon The biology and enzymology of protein N-myristoylation J. Biol. Chem. 276 2001 9501 9504
3. R.V. Rajala, R.S. Datla, T.N. Moyana, R. Kakkar, S.A. Carlsen, and R.K. Sharma N-myristoyltransferase Mol. Cell. Biochem. 204 2000 135 155
4. M.D. Resh Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins Biochim. Biophys. Acta 1451 1999 1 16
5. J.A. Boutin Myristoylation Cell Signal. 9 1997 15 35
6. S.M. Arfin, R.L. Kendall, L. Hall, L.H. Weaver, A.E. Stewart, and B.W. Matthews Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes Proc. Natl. Acad. Sci. USA 92 1995 7714 7718
7. K.W. Walker, and R.A. Bradshaw Yeast methionine aminopeptidase I, alteration of substrate specificity by site-directed mutagenesis J. Biol. Chem. 274 1999 13403 13409
8. X. Li, and Y.H. Chang Evidence that the human homologue of a rat initiation factor-2 associated protein (p67) is a methionine aminopeptidase Biochem. Biophys. Res. Commun. 227 1996 152 159
9. M.K. Ray, B. Datta, A. Chakraborty, A. Chattopadhyay, S. Meza-Keuthen, and N.K. Gupta The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells Proc. Natl. Acad. Sci. USA 89 1992 539 543
10. N. Sin, L. Meng, M.Q.W. Wang, J.J. Wen, W.G. Bornmann, and C.M. Crews The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 Proc. Natl. Acad. Sci. USA 94 1997 6099 6103
11. E.C. Griffith, Z. Su, B.E. Turk, S. Chen, Y.W. Chang, and Z. Wu Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin Chem. Biol. 4 1997 461 471
12. J. Abe, W. Zhou, N. Takuwa, J. Taguchi, K. Kurokawa, M. Kumada, and Y. Takuwa A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial cells Cancer Res. 54 1994 3407 3412
13. A. Catalano, M. Romano, I. Robuffo, L. Strizzi, and A. Procopio Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity Am. J. Pathol. 159 2001 721 731
14. T. Kanno, H. Endo, K. Takeuchi, Y. Morishita, M. Fukayama, and S. Mori High expression of methionine aminopeptidase type 2 in germinal center B cells and their neoplastic counterparts Lab. Invest. 82 2002 893 901
15. P. Selvakumar, A. Lakshmikuttyamma, R. Kanthan, S.C. Kanthan, J.R. Dimmock, and R.K. Sharma High expression of methionine aminopeptidase 2 in human colorectal adenocarcinomas Clin. Cancer Res. 10 2004 2771 2775
16. c-src protein kinase activity in human colon carcinoma Proc. Natl. Acad. Sci. USA 84 1987 2251 2255
17. J. Park, A.I. Meisler, and C.A. Cartwright c-Yes tyrosine kinase activity in human colon carcinoma Oncogene 8 1993 2627 2635
18. J.S. Biscardi, R.C. Ishizawar, C.M. Silva, and S.J. Parsons Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer Breast Cancer Res. 2 2000 203 210
19. C.A. Cartwright, S. Mamajiwalla, S.A. Skolnick, W. Eckhart, and D.R. Burgess Intestinal crypt cells contain higher levels of cytoskeletal-associated pp60c-src protein tyrosine kinase activity than do differentiated enterocytes Oncogene 8 1993 1033 1039
20. F.R. Cross, E.A. Garber, D. Pellman, and H. Hanafusa A short sequence in the p60src N terminus is required for p60src myristoylation and membrane association and for cell transformation Mol. Cell. Biol. 4 1984 1834 1842
21. M. Hamaguchi, and H. Hanafusa Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation Proc. Natl. Acad. Sci. USA. 84 1987 2312 2316
22. B.A. Magnuson, R.V. Raju, T.N. Moyana, and R.K. Sharma Increased N-myristoyltransferase activity observed in rat and human colonic tumors J. Natl. Cancer Inst. 87 1995 1630 1635
23. R.V. Raju, T.N. Moyana, and R.K. Sharma N-Myristoyltransferase overexpression in human colorectal adenocarcinomas Exp. Cell Res. 235 1997 145 154
24. R.V. Rajala, J.M. Radhi, R. Kakkar, R.S. Datla, and R.K. Sharma Increased expression of N-myristoyltransferase in gallbladder carcinomas Cancer 88 2000 1992 1999
25. M.J. King, and R.K. Sharma Identification, purification and characterization of a membrane-associated N-myristoyltransferase inhibitor protein from bovine brain Biochem. J. 291 1993 635 639
26. R.L. Felsted, C.J. Glover, and K. Hartman Protein N-myristoylation as a chemotherapeutic target for cancer J. Natl. Cancer Inst. 87 1995 1571 1573
27. R.V. Rajala, S. Dehm, X. Bi, K. Bonham, and R.K. Sharma Expression of N-myristoyltransferase inhibitor protein and its relationship to c-Src levels in human colon cancer cell lines Biochem. Biophys. Res. Commun. 273 2000 1116 1120
28. R.V. Raju, R.S. Datla, and R.K. Sharma Overexpression of human N-myristoyltransferase utilizing a T7 polymerase gene expression system Protein Expr. Purif. 7 1996 431 437
29. M.J. King, and R.K. Sharma N-Myristoyl transferase assay using phosphocellulose paper binding Anal. Biochem. 199 1991 149 153
30. R.V. Raju, and R.K. Sharma Preparation and assay of myristoyl-CoA:protein N-myristoyltransferase Methods Mol. Biol. 116 1999 193 211
31. S. Nirasawa, Y. Nakajima, Z.Z. Zhang, M. Yoshida, and K. Hayashi Intramolecular chaperone and inhibitor activities of a propeptide from a bacterial zinc aminopeptidase Biochem. J. 341 1999 25 31
32. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
33. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
34. H. Towbin, T. Staehelin, and J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl. Acad. Sci. USA 76 1979 4350 4354
35. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
36. S.M. Dehm, and H. Bonham SRC gene expression in human cancer: the role of transcriptional activation Biochem. Cell Biol. 82 2004 263 274
37. P.J. Casey Protein lipidation in cell signaling Science 268 1995 221 225
38. M.D. Resh Interaction of tyrosine kinase oncoproteins with cellular membranes Biochim. Biophys. Acta 1155 1993 307 322
39. M.D. Resh Myristoylation and palmitoylation of Src family members: the fats of the matter Cell 76 1994 411 413
40. E.C. Griffith, Z. Su, S. Niwayama, C.A. Ramsay, Y.H. Chang, and J.O. Liu Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2 Proc. Natl. Acad. Sci. USA 95 1998 15183 15188
41. H.G. Yu, L.L. Yu, Y. Yang, H.S. Luo, J.P. Yu, J.J. Meier, H. Schrader, A. Bastian, W.E. Schmidt, and F. Schmitz Increased expression of RelA/nuclear factor-kappa B protein correlates with colorectal tumorigenesis Oncology 65 2003 37 45
42. K.E. Valassiadou, K. Stefanaki, M. Tzardi, G. Datseris, V. Georgoulias, J. Melissas, D.D. Tsiftsis, G. Delides, and P. Kanavaros Immunohistochemical expression of p53, bcl-2, mdm2 and waf1/p21 proteins in colorectal adenocarcinomas Anticancer Res. 17 1997 2571 2576
43. J. Cheng, K. Ogawa, K. Kuriki, Y. Yokoyama, T. Kamiya, K. Seno, H. Okuyama, J. Wang, C. Luo, T. Fujii, H. Ichikawa, T. Shirai, and S. Tokudome Increased intake of n-3 polyunsaturated fatty acids elevates the level of apoptosis in the normal sigmoid colon of patients polypectomized for adenomas/tumors Cancer Lett. 193 2003 17 24
44. A. Reinacher-Schick, A. Schoeneck, U. Graeven, I. Schwarte-Waldhoff, and W. Schmiegel Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cells Carcinogenesis 24 2003 443 451
45. T. Chen, I. Yang, R. Irby, K.H. Shain, H.G. Wang, J. Quackenbush, D. Coppola, J.Q. Cheng, and T.J. Yeatman Regulation of caspase expression and apoptosis by adenomatous polyposis coli Cancer Res. 63 2003 4368 4374