Gene therapy: X-SCID transgene leukaemogenicity

Nature

Volumn 443, Issue 7109, 2006, Pages

  Thrasher, Adrian J ^a,b   Gaspar, H Bobby ^a,b   Baum, Christopher ^c,d   Modlich, Ute ^c   Schambach, Axel ^c   Candotti, Fabio ^e   Otsu, Makoto ^f   Sorrentino, Brian ^g   Scobie, Linda ^h   Cameron, Ewan ^h   Blyth, Karen ^h   Neil, Jim ^h   Abina, Salima Hacein Bey ^i,j   Cavazzana Calvo, Marina ^i,j,k   Fischer, Alain ^i,j,k  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF TOKYO   (Japan)

^g ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^h UNIVERSITY OF GLASGOW   (United Kingdom)

ⁱ HÔPITAL NECKER ENFANTS MALADES   (France)

^j ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^k UNIVERSITÉ PARIS DESCARTES   (France)

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Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2 RECEPTOR GAMMA; JANUS KINASE 3; LENTIVIRUS VECTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LMO2; UNCLASSIFIED DRUG;

GENE; GENE EXPRESSION; TUMOR;

ARTICLE; BONE MARROW CELL; CARCINOGENESIS; COMBINED IMMUNODEFICIENCY; GENE; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE OVEREXPRESSION; GENE THERAPY; HEMATOLOGIC MALIGNANCY; IL2RG GENE; LEUKEMOGENESIS; LMO2 GENE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SIGNAL TRANSDUCTION; SURVIVAL; VIRAL GENE DELIVERY SYSTEM; X LINKED SEVERE COMBINED IMMUNE DEFICIENCY;

EID: 33748939587     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05219     Document Type: Article

References (10)

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