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Volumn 41, Issue 7, 2003, Pages 919-942

A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; BENZOIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; CINNAMIC ACID DERIVATIVE; ESTER DERIVATIVE; FORMIC ACID DERIVATIVE; FRAGRANCE; HEXANOIC ACID DERIVATIVE; ISOBUTYRIC ACID DERIVATIVE; ISOVALERIC ACID; LAVENDER OIL; LINALOOL; PHENYLACETIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE;

EID: 0013080251     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(03)00016-4     Document Type: Review
Times cited : (127)

References (101)
  • 2
    • 0002467542 scopus 로고
    • Biotransformation and bioactivation of xenobiotics by the kidney
    • D.H. Hutson, J. Caldwell, & G.D. Paulson. New York: Taylor and Francis
    • Anders M.W. Biotransformation and bioactivation of xenobiotics by the kidney. Hutson D.H., Caldwell J., Paulson G.D. Intermediary Xenobiotic Metabolism in Animals. 1989;81-97 Taylor and Francis, New York.
    • (1989) Intermediary Xenobiotic Metabolism in Animals , pp. 81-97
    • Anders, M.W.1
  • 5
    • 0036926348 scopus 로고    scopus 로고
    • Consumer exposure to fragrance ingredients: Providing estimates for safety evaluation
    • Cadby, P., Troy, W.R., Vey, M., (2002). Consumer exposure to fragrance ingredients: Providing estimates for safety evaluation. Regulatory Toxicology and Pharmacology 36, 246-252.
    • (2002) Regulatory Toxicology and Pharmacology , vol.36 , pp. 246-252
    • Cadby, P.1    Troy, W.R.2    Vey, M.3
  • 6
    • 0021270649 scopus 로고
    • Metabolism of geraniol and linalool in the rat and effects on liver and lung microsomal enzymes
    • Chadha A., Madyastha K.M. Metabolism of geraniol and linalool in the rat and effects on liver and lung microsomal enzymes. Xenobiotica. 14:1984;365-374.
    • (1984) Xenobiotica , vol.14 , pp. 365-374
    • Chadha, A.1    Madyastha, K.M.2
  • 8
    • 0018861257 scopus 로고
    • Mutagenic potential of allyl and allylic compounds. Structure-activity relationship as determined by alkylating and direct in-vitro mutagenic properties
    • Eder E., Neudecker T., Lutz D., Henschler D. Mutagenic potential of allyl and allylic compounds. Structure-activity relationship as determined by alkylating and direct in-vitro mutagenic properties. Biochemical Pharmacology. 29:1980;993-998.
    • (1980) Biochemical Pharmacology , vol.29 , pp. 993-998
    • Eder, E.1    Neudecker, T.2    Lutz, D.3    Henschler, D.4
  • 9
    • 0020446036 scopus 로고
    • Mutagenic properties of allylic and α,β-unsaturated compounds: Considerations of alkylating mechanisms
    • Eder E., Henschler D., Neudecker T. Mutagenic properties of allylic and α,β-unsaturated compounds. considerations of alkylating mechanisms Xenobiotica. 12:1982;831-848.
    • (1982) Xenobiotica , vol.12 , pp. 831-848
    • Eder, E.1    Henschler, D.2    Neudecker, T.3
  • 10
    • 0020057065 scopus 로고
    • Correlation of alkylating and mutagenic activities of allyl and allylic compounds: Standard alkylation test vs kinetic investigation
    • Eder E., Neudecker T., Lutz D., Henschler D. Correlation of alkylating and mutagenic activities of allyl and allylic compounds. standard alkylation test vs kinetic investigation Chemico-Biological Interactions. 38:1982;303-315.
    • (1982) Chemico-Biological Interactions , vol.38 , pp. 303-315
    • Eder, E.1    Neudecker, T.2    Lutz, D.3    Henschler, D.4
  • 12
    • 0001117852 scopus 로고
    • Recent progress in the consideration of flavoring ingredients under the Food Additives Amendment. 3. Gras Substances
    • Recent progress in the consideration of flavoring ingredients under the Food Additives Amendment. 3. Gras Substances. Food Technology. 19:1965;151-197.
    • (1965) Food Technology , vol.19 , pp. 151-197
  • 13
    • 0038737998 scopus 로고
    • Recent progress in the consideration of flavoring ingredients under the Food Additives Amendment. 10. GRAS substances
    • Recent progress in the consideration of flavoring ingredients under the Food Additives Amendment. 10. GRAS substances. Food Technology. 31:1977;65-74.
    • (1977) Food Technology , vol.31 , pp. 65-74
  • 16
    • 0038061543 scopus 로고
    • Studies on compounded perfumes for toilet goods. On the non-irritative compounded perfumes for soaps
    • Fujii T., Furukawa S., Suzuki S. Studies on compounded perfumes for toilet goods. On the non-irritative compounded perfumes for soaps. Yukugaku. 21:1972;904-908.
    • (1972) Yukugaku , vol.21 , pp. 904-908
    • Fujii, T.1    Furukawa, S.2    Suzuki, S.3
  • 20
    • 0002157794 scopus 로고
    • Cutaneous safety of fragrance material as measured by the maximization test
    • Greif N. Cutaneous safety of fragrance material as measured by the maximization test. American Perfumer and Cosmetics. 82:1967;54-57.
    • (1967) American Perfumer and Cosmetics , vol.82 , pp. 54-57
    • Greif, N.1
  • 29
    • 0026410863 scopus 로고
    • Investigations of animal blood samples after fragrance drug inhalation by gas chromatography/mass spectrometry with chemical ionization and selected ion monitoring
    • Jirovetz L., Jager W., Buchbauer G., Nikiforov A., Raverdino V. Investigations of animal blood samples after fragrance drug inhalation by gas chromatography/mass spectrometry with chemical ionization and selected ion monitoring. Biological Mass Spectrometry. 20:1991;801-803.
    • (1991) Biological Mass Spectrometry , vol.20 , pp. 801-803
    • Jirovetz, L.1    Jager, W.2    Buchbauer, G.3    Nikiforov, A.4    Raverdino, V.5
  • 31
    • 0031397771 scopus 로고    scopus 로고
    • Evaluation of Certain Food Additives and Contaminants. Forty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives
    • JECFA (Joint Expert Committee on Food Additives), 1997. Evaluation of Certain Food Additives and Contaminants. Forty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 868.
    • (1997) WHO Technical Report Series, No. 868 , vol.868
  • 33
    • 0000351012 scopus 로고
    • The tolerability of benzoic acid in chronic feeding experiments
    • Kieckebusch W., Lang K. The tolerability of benzoic acid in chronic feeding experiments. Arzneimittel-Forschung. 10:1960;1001-1003.
    • (1960) Arzneimittel-Forschung , vol.10 , pp. 1001-1003
    • Kieckebusch, W.1    Lang, K.2
  • 38
    • 0019168278 scopus 로고
    • Mutagenic effects of allylic alcohols and their corresponding aldehydes
    • Lutz D., Neudecker T., Eder E. Mutagenic effects of allylic alcohols and their corresponding aldehydes. Archives of Pharmacology. 311(suppl):1980;R25.
    • (1980) Archives of Pharmacology , vol.311 , Issue.SUPPL. , pp. 25
    • Lutz, D.1    Neudecker, T.2    Eder, E.3
  • 40
    • 0012130575 scopus 로고
    • Comparative studies on the irritancy of oils and synthetic perfumes to the skin of rabbit, guinea pig, rat, miniature swine and man
    • Motoyoshi K., Toyoshima Y., Sato M., Yoshimura M. Comparative studies on the irritancy of oils and synthetic perfumes to the skin of rabbit, guinea pig, rat, miniature swine and man. Cosmetics and Toiletries. 94:1979;41-48.
    • (1979) Cosmetics and Toiletries , vol.94 , pp. 41-48
    • Motoyoshi, K.1    Toyoshima, Y.2    Sato, M.3    Yoshimura, M.4
  • 42
    • 0038737984 scopus 로고
    • A report on studies of anthelmintic actions of principles of volatile oils III. Toxicity for mice and the efficacy against pig ascaria and earthworm muscles
    • Nozawa Y. A report on studies of anthelmintic actions of principles of volatile oils III. Toxicity for mice and the efficacy against pig ascaria and earthworm muscles. Sapporo Igaku Zasshi. 3:1952;73-77.
    • (1952) Sapporo Igaku Zasshi , vol.3 , pp. 73-77
    • Nozawa, Y.1
  • 46
    • 0013170556 scopus 로고
    • Relationship of molecular configuration to the activity of furocoumarins which increase the cutaneous responses following long wave ultraviolet radiation
    • Pathak M.A., Fitzpatrick T.B. Relationship of molecular configuration to the activity of furocoumarins which increase the cutaneous responses following long wave ultraviolet radiation. Journal of Investigative Dermatology 32, Part. 2:1959;255-262.
    • (1959) Journal of Investigative Dermatology 32, Part , vol.2 , pp. 255-262
    • Pathak, M.A.1    Fitzpatrick, T.B.2
  • 47
    • 0038399735 scopus 로고
    • Unpublished report from Trubek Laboratories, Inc. Project No. 73800, 11 August. Report number 29150. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1958a. Toxicological screening of citronellol and linalool in rats. Class VI. Unpublished report from Trubek Laboratories, Inc. Project No. 73800, 11 August. Report number 29150. (RIFM, Woodcliff Lake, NJ, USA).
    • (1958) Toxicological Screening of Citronellol and Linalool in Rats. Class VI
  • 49
    • 85031168058 scopus 로고
    • Unpublished report from Hoffmann-LaRoche, 20 September. Report number 30642. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1967a. Acute toxicity, eye and skin irritation test of fragrance materials. Unpublished report from Hoffmann-LaRoche, 20 September. Report number 30642. (RIFM, Woodcliff Lake, NJ, USA).
    • (1967) Acute Toxicity, Eye and Skin Irritation Test of Fragrance Materials
  • 50
    • 85031168058 scopus 로고
    • Unpublished report from Hoffmann-LaRoche, 20 August. Report number 30645. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1967b. Acute toxicity, eye and skin irritation test of fragrance materials. Unpublished report from Hoffmann-LaRoche, 20 August. Report number 30645. (RIFM, Woodcliff Lake, NJ, USA).
    • (1967) Acute Toxicity, Eye and Skin Irritation Test of Fragrance Materials
  • 51
    • 0038399827 scopus 로고
    • Unpublished report from BASF, 29 July. Report number 4418. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1969. Acute toxicity, irritation, and sensitization studies on linalyl acetate. Unpublished report from BASF, 29 July. Report number 4418. (RIFM, Woodcliff Lake, NJ, USA).
    • (1969) Acute Toxicity, Irritation, and Sensitization Studies on Linalyl Acetate
  • 52
    • 85031174539 scopus 로고
    • RIFM report number 2735, September 14. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1970a. Acute dermal toxicity study in rabbits. RIFM report number 2735, September 14. (RIFM, Woodcliff Lake, NJ, USA).
    • (1970) Acute Dermal Toxicity Study in Rabbits
  • 53
    • 84995961650 scopus 로고
    • RIFM report number 1760, October 7. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1970b. The contact sensitizing potential of fragrance materials in humans. RIFM report number 1760, October 7. (RIFM, Woodcliff Lake, NJ, USA).
    • (1970) The Contact Sensitizing Potential of Fragrance Materials in Humans
  • 54
    • 20444405544 scopus 로고
    • RIFM report number 2536, September 20 and November 1. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1972. Acute toxicity studies in rats and rabbits. RIFM report number 2536, September 20 and November 1. (RIFM, Woodcliff Lake, NJ, USA).
    • (1972) Acute Toxicity Studies in Rats and Rabbits
  • 55
    • 20444405544 scopus 로고
    • RIFM report number 2021, May 14 and 18. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1973a. Acute toxicity studies in rats and rabbits. RIFM report number 2021, May 14 and 18. (RIFM, Woodcliff Lake, NJ, USA).
    • (1973) Acute Toxicity Studies in Rats and Rabbits
  • 56
    • 0038061539 scopus 로고
    • RIFM report number 2033, March 6. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1973b. Acute oral and dermal toxicity studies. RIFM report number 2033, March 6. (RIFM, Woodcliff Lake, NJ, USA).
    • (1973) Acute Oral and Dermal Toxicity Studies
  • 57
    • 84995931907 scopus 로고
    • RIFM report number 1802, August 12 and October 9 and 10. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1973c. Report on human maximization studies. RIFM report number 1802, August 12 and October 9 and 10. (RIFM, Woodcliff Lake, NJ, USA).
    • (1973) Report on Human Maximization Studies
  • 58
    • 20444395673 scopus 로고
    • RIFM report number 1778, January 23 and August 22. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.)., 1974a. Acute toxicity studies. RIFM report number 1778, January 23 and August 22. (RIFM, Woodcliff Lake, NJ, USA).
    • (1974) Acute Toxicity Studies
  • 59
    • 84995931907 scopus 로고
    • RIFM report number 1801, May 31 and August 19. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1974b. Report on human maximization studies. RIFM report number 1801, May 31 and August 19. (RIFM, Woodcliff Lake, NJ, USA).
    • (1974) Report on Human Maximization Studies
  • 60
    • 84995931907 scopus 로고
    • RIFM report number 1779, June 6 and August 12. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1974c. Report on human maximization studies. RIFM report number 1779, June 6 and August 12. (RIFM, Woodcliff Lake, NJ, USA).
    • (1974) Report on Human Maximization Studies
  • 61
    • 20444405544 scopus 로고
    • RIFM report number 2024, January 30. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1975a. Acute toxicity studies in rats, mice, and rabbits. RIFM report number 2024, January 30. (RIFM, Woodcliff Lake, NJ, USA).
    • (1975) Acute Toxicity Studies in Rats, Mice, and Rabbits
  • 62
    • 0345321308 scopus 로고
    • RIFM report number 2020, April 10. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1975b. Acute toxicity studies on rats, rabbits and guinea pigs. RIFM report number 2020, April 10. (RIFM, Woodcliff Lake, NJ, USA).
    • (1975) Acute Toxicity Studies on Rats, Rabbits and Guinea Pigs
  • 63
    • 84995931907 scopus 로고
    • RIFM report number 1799, April 9 and October 24. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1975c. Report on human maximization studies. RIFM report number 1799, April 9 and October 24. (RIFM, Woodcliff Lake, NJ, USA).
    • (1975) Report on Human Maximization Studies
  • 64
    • 84995931907 scopus 로고
    • RIFM report number 1798, May 6. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1975d. Report on human maximization studies. RIFM report number 1798, May 6. (RIFM, Woodcliff Lake, NJ, USA).
    • (1975) Report on Human Maximization Studies
  • 66
    • 85031171635 scopus 로고
    • RIFM report number 4001, April 4. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1980. Ninety day subacute dermal toxicity with linalool in rats. RIFM report number 4001, April 4. (RIFM, Woodcliff Lake, NJ, USA).
    • (1980) Ninety Day Subacute Dermal Toxicity with Linalool in Rats
  • 67
    • 85031172654 scopus 로고
    • Report from Lorillard Tobacco Company, 31 August, cited in Heck et al., 1989. Report number 35826. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1982a. Mutagenicity evaluation of linalool in the mouse lymphoma forward mutation assay. Report from Lorillard Tobacco Company, 31 August, cited in Heck et al., 1989. Report number 35826. (RIFM, Woodcliff Lake, NJ, USA).
    • (1982) Mutagenicity Evaluation of Linalool in the Mouse Lymphoma Forward Mutation Assay
  • 68
    • 0038061532 scopus 로고
    • RIFM report number 1643, April 27 and 30 and September 14. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1982b. Report on human maximization studies. RIFM report number 1643, April 27 and 30 and September 14. (RIFM, Woodcliff Lake, NJ, USA).
    • (1982) Report on Human Maximization Studies
  • 69
    • 84996969383 scopus 로고
    • Unpublished report from Lorillard Tobacco Company, 20 July. Report number 35823. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1983a. Mutagenicity evaluation of linalool in the Ames Salmonella/microsome plate test. Unpublished report from Lorillard Tobacco Company, 20 July. Report number 35823. (RIFM, Woodcliff Lake, NJ, USA).
    • (1983) Mutagenicity Evaluation of Linalool in the Ames Salmonella/Microsome Plate Test
  • 71
    • 85031178500 scopus 로고
    • Unpublished report from Lorillard Tobacco Company, 12 January. Report number 36660. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1984a. A 14-Day single dose subacute toxicity study in the rat. Unpublished report from Lorillard Tobacco Company, 12 January. Report number 36660. (RIFM, Woodcliff Lake, NJ, USA).
    • (1984) A 14-Day Single Dose Subacute Toxicity Study in the Rat
  • 72
    • 0037723917 scopus 로고
    • RIFM report number 1795, June 1. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1984b. Acute dermal irritation study in rabbits. RIFM report number 1795, June 1. (RIFM, Woodcliff Lake, NJ, USA).
    • (1984) Acute Dermal Irritation Study in Rabbits
  • 73
    • 0038737977 scopus 로고
    • RIFM report number 3099, June 1. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1985. Acute dermal irritation study in rabbits. RIFM report number 3099, June 1. (RIFM, Woodcliff Lake, NJ, USA).
    • (1985) Acute Dermal Irritation Study in Rabbits
  • 74
    • 85031164112 scopus 로고
    • Report from Lorillard Tobacco Company, 5 May, cited in Heck et al., 1989. Report number 35825. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1986a. Unscheduled DNA synthesis in rat primary hepatocytes. Report from Lorillard Tobacco Company, 5 May, cited in Heck et al., 1989. Report number 35825. (RIFM, Woodcliff Lake, NJ, USA).
    • (1986) Unscheduled DNA Synthesis in Rat Primary Hepatocytes
  • 75
    • 85031163536 scopus 로고
    • Unpublished report from Lorillard Tobacco Company, 17 July. Report number 36498. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1986b. A 14-day single dose subacute toxicity study. Unpublished report from Lorillard Tobacco Company, 17 July. Report number 36498. (RIFM, Woodcliff Lake, NJ, USA).
    • (1986) A 14-Day Single Dose Subacute Toxicity Study
  • 76
    • 85031165688 scopus 로고
    • RIFM report number 5664, June 1. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1986c. Acute dermal irritation study in rabbits. RIFM report number 5664, June 1. (RIFM, Woodcliff Lake, NJ, USA).
    • (1986) Acute Dermal Irritation Study in Rabbits
  • 77
    • 0038061458 scopus 로고
    • Unpublished report from Lorillard Tobacco Company. 30 January. Report number 36497. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1987. Mutagenicity evaluation of lynalyl acetate in the Ames Salmonella/microsome reverse mutation assay. Unpublished report from Lorillard Tobacco Company. 30 January. Report number 36497. (RIFM, Woodcliff Lake, NJ, USA).
    • (1987) Mutagenicity Evaluation of Lynalyl Acetate in the Ames Salmonella/Microsome Reverse Mutation Assay
  • 79
    • 85031163109 scopus 로고
    • Submission to EPA by Rhone-Poulenc Inc., 11 September. Report number 23272. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1992. Linalool and dehydolinalool. Acute toxicity and local tolerance. Submission to EPA by Rhone-Poulenc Inc., 11 September. Report number 23272. (RIFM, Woodcliff Lake, NJ, USA).
    • (1992) Linalool and Dehydolinalool. Acute Toxicity and Local Tolerance
  • 80
    • 84996847728 scopus 로고
    • Unpublished report from Lorillard Tobacco Company, 3 March. Report number 35827. (RIFM, Woodcliff Lake, NJ, USA)
    • ± mouse lymphoma forward mutation assay with a confirmatory assay. Unpublished report from Lorillard Tobacco Company, 3 March. Report number 35827. (RIFM, Woodcliff Lake, NJ, USA).
    • (1994) ± Mouse Lymphoma Forward Mutation Assay with a Confirmatory Assay
  • 81
    • 85031171285 scopus 로고    scopus 로고
    • Unpublished report from Takasago International Corporation, 9 December. Report number 31609. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1997a. Human patch test of linalyl acetate. Unpublished report from Takasago International Corporation, 9 December. Report number 31609. (RIFM, Woodcliff Lake, NJ, USA).
    • (1997) Human Patch Test of Linalyl Acetate
  • 82
    • 85031169955 scopus 로고    scopus 로고
    • Unpublished report from Takasago International Corporation, 9 December. Report number 31606. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 1997b. Delayed contact hypersensitivity study of linalyl acetate in guinea pigs. Unpublished report from Takasago International Corporation, 9 December. Report number 31606. (RIFM, Woodcliff Lake, NJ, USA).
    • (1997) Delayed Contact Hypersensitivity Study of Linalyl Acetate in Guinea Pigs
  • 84
    • 0037723914 scopus 로고    scopus 로고
    • Unpublished report from Hoffmann-LaRoche, 18 November. Report number 38577. (RIFM, Woodcliff Lake, NJ, USA)
    • RIFM (Research Institute for Fragrance Materials, Inc.), 2001. Micronucleus test in bone marrow cells of the mouse with linalool. Unpublished report from Hoffmann-LaRoche, 18 November. Report number 38577. (RIFM, Woodcliff Lake, NJ, USA).
    • (2001) Micronucleus Test in Bone Marrow Cells of the Mouse with Linalool
  • 86
    • 0010053399 scopus 로고
    • A mutagenic screening of various herbs, spices, and food additives
    • Rockwell P., Raw I. A mutagenic screening of various herbs, spices, and food additives. Nutrition and Cancer. 1:1979;10-15.
    • (1979) Nutrition and Cancer , vol.1 , pp. 10-15
    • Rockwell, P.1    Raw, I.2
  • 87
    • 0013792561 scopus 로고
    • Chronic toxicity of essential oils and certain other products of natural origin
    • Roe F.J.C., Field W.E.H. Chronic toxicity of essential oils and certain other products of natural origin. Food and Cosmetics Toxicology. 3:1965;311-324.
    • (1965) Food and Cosmetics Toxicology , vol.3 , pp. 311-324
    • Roe, F.J.C.1    Field, W.E.H.2
  • 89
    • 0024353207 scopus 로고
    • Modifying effects of components of plant essence on the induction of sister-chromatid exchanges in cultured Chinese hamster ovary cells
    • Sasaki Y.F., Imanishi H., Phta T., Shirasu Y. Modifying effects of components of plant essence on the induction of sister-chromatid exchanges in cultured Chinese hamster ovary cells. Mutation Research. 226:1989;103-110.
    • (1989) Mutation Research , vol.226 , pp. 103-110
    • Sasaki, Y.F.1    Imanishi, H.2    Phta, T.3    Shirasu, Y.4
  • 90
    • 0000191215 scopus 로고
    • Role of carboxylesterases in xenobiotic metabolism
    • E. Hodgson, J.R. Bend, & R.P. Philpot. New York: Elsevier
    • Satoh T. Role of carboxylesterases in xenobiotic metabolism. Hodgson E., Bend J.R., Philpot R.P. Reviews in Biochemical Toxicology. vol. 8. 1987;155-181 Elsevier, New York.
    • (1987) Reviews in Biochemical Toxicology , vol.8 , pp. 155-181
    • Satoh, T.1
  • 91
    • 0017883460 scopus 로고
    • The sensitization potential of some perfume ingredients tested using a modified Draize procedure
    • Sharp D.W. The sensitization potential of some perfume ingredients tested using a modified Draize procedure. Toxicology. 9:1978;261-271.
    • (1978) Toxicology , vol.9 , pp. 261-271
    • Sharp, D.W.1
  • 92
    • 0015717433 scopus 로고
    • Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice
    • Stoner G.D., Shimkin M.B., Kniazeff A.J., Weisburger J.H., Weisburger E.K., Go G.B. Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice. Cancer Research. 33:1973;3069-3085.
    • (1973) Cancer Research , vol.33 , pp. 3069-3085
    • Stoner, G.D.1    Shimkin, M.B.2    Kniazeff, A.J.3    Weisburger, J.H.4    Weisburger, E.K.5    Go, G.B.6
  • 93
    • 85031166158 scopus 로고
    • H. Maarse, C.A. Visscher, L.C. Willemsens, L.M. Nijssen, Boelens M.H.; TNO Nutrition and Food Research Center, Zeist, The Netherlands
    • Volatile Components in Food-Qualitative and Quantitative Data. Supplement 5 to the 6th Ed. Maarse H., Visscher C.A., Willemsens L.C., Nijssen L.M., Boelens M.H. 1994; TNO Nutrition and Food Research Center, Zeist, The Netherlands.
    • (1994) Volatile Components in Food-Qualitative and Quantitative Data. Supplement 5 to the 6th Ed.
  • 94
    • 85031177346 scopus 로고
    • Doctoral Dissertation: The comparative respiratory irritation potential of fourteen fragrance raw materials. Private communication to RIFM. Report number 9011
    • Troy, W.R., 1977. Doctoral Dissertation: The comparative respiratory irritation potential of fourteen fragrance raw materials. Private communication to RIFM. Report number 9011.
    • (1977)
    • Troy, W.R.1
  • 97
    • 0037723909 scopus 로고
    • Immunotoxicity assessment of flavoring ingredients using a rapid and economical screen
    • Vollmuth T.A., Heck J.D., Ratajczak H.V., Thomas P.T. Immunotoxicity assessment of flavoring ingredients using a rapid and economical screen. The Toxicologist. 9:1989;206.
    • (1989) The Toxicologist , vol.9 , pp. 206
    • Vollmuth, T.A.1    Heck, J.D.2    Ratajczak, H.V.3    Thomas, P.T.4
  • 98
    • 0025972689 scopus 로고
    • Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol)
    • Wattenberg L.W. Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol). Carcinogenesis. 12:1991;151-152.
    • (1991) Carcinogenesis , vol.12 , pp. 151-152
    • Wattenberg, L.W.1
  • 99
    • 0003395078 scopus 로고
    • Detoxification Mechanisms. The Metabolism and Detoxication of Drugs, Toxic Substances, and Other Organic Compounds
    • London: Chapman and Hall Ltd. pp. 67-69
    • Williams R.T. Detoxification Mechanisms. The Metabolism and Detoxication of Drugs, Toxic Substances, and Other Organic Compounds. 2nd Edn:1959;Chapman and Hall Ltd, London. pp. 67-69.
    • (1959) 2nd Edn
    • Williams, R.T.1
  • 100
    • 0010420023 scopus 로고
    • Mutagenic and antimutagenic activities of flavoring agents used in foodstuffs
    • Yoo Y.S. Mutagenic and antimutagenic activities of flavoring agents used in foodstuffs. Journal of Osaka Shiritso Daigaku Igaku Zasshi. 34:1986;267-288.
    • (1986) Journal of Osaka Shiritso Daigaku Igaku Zasshi , vol.34 , pp. 267-288
    • Yoo, Y.S.1


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