LPS differentially affects vasoconstrictor responses: A potential role for RGS16?

Journal of Physiology and Biochemistry

Volumn 65, Issue 1, 2009, Pages 71-83

  Hendriks Balk, M C ^a   Tjon Atsoi, M ^a   Hajji, N ^a   Alewijnse, A E ^a   Peters, S L M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Aorta; Lipopolysaccharide; Regulator of G protein signalling; Vasoconstriction

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; BACTERIUM LIPOPOLYSACCHARIDE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; PHENYLEPHRINE; RGS PROTEIN; RGS16 PROTEIN; RGS2 PROTEIN; RGS3 PROTEIN; RGS4 PROTEIN; RGS5 PROTEIN; SEROTONIN; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 67249117614     PISSN: 11387548     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03165971     Document Type: Article

References (31)

1. Burnier, M., Centeno, G., Waeber, G., Centeno, C., Burki, E. (1995): Effect of endotoxin on the angiotensin II receptor in cultured vascular smooth muscle cells. Br J Pharmacol, 116, 2524-2530.
2. Calo, L.A., Pagnin, E., Ceolotto, G., Davis, P.A., Schiavo, S., Papparella, I., Semplicini, A., Pessina, A.C. (2008): Silencing regulator of G protein signaling-2 (RGS-2) increases angiotensin II signaling: insights into hypertension from findings in Bartter's/Gitelman's syndromes. J Hypertens, 26, 938-945.
3. Calo, L.A., Pagnin, E., Davis, P.A., Sartori, M., Ceolotto, G., Pessina, A.C., Semplicini, A. (2004): Increased expression of regulator of G protein signaling-2 (RGS-2) in Bartter's/Gitelman's syndrome. A role in the control of vascular tone and implication for hypertension. J Clin Endocrinol Metab, 89, 4153-4157. (Pubitemid 39071528)
4. Cho, H., Park, C., Hwang, I.Y., Han, S. B., Schimel, D., Despres, D., Kehrl, J.H. (2008): Rgs5 targeting leads to chronic low blood pressure and a lean body habitus. Mol Cell Biol, 28, 2590-2597. (Pubitemid 351542360)
5. Contestabile, A. (2008): Regulation of transcription factors by nitric oxide in neurons and in neural-derived tumor cells. Prog Neurobiol, 84, 317-328.
6. Dauphinee, S.M., Karsan, A. (2006): Lipopolysaccharide signaling in endothelial cells. Lab Invest, 86, 9-22. (Pubitemid 43250964)
7. Groeneveld, A.B., Bronsveld, W., Thijs, L.G. (1986): Hemodynamic determinants of mortality in human septic shock. Surgery, 99, 140-153. (Pubitemid 16144912)
8. Gruetter, C.A., Ryan, E.T., Schoepp, D.D. (1987): Endothelium enhances tachyphylaxis to angiotensins II and III in rat aorta. Eur J Pharmacol, 143, 139-142. (Pubitemid 18046814)
9. Hattori, Y., Hattori, S., Kasai, K. (2003): Lipopolysaccharide activates Akt in vascular smooth muscle cells resulting in induction of inducible nitric oxide synthase through nuclear factor-kappa B activation. Eur J Pharmacol, 481, 153-158. (Pubitemid 37464964)
10. Hendriks-Balk, M.C., Michel, M.C., Alewijnse, A.E. (2007): Pitfalls in the normalization of real-time polymerase chain reaction data. Basic Res Cardiol, 102, 195-197. (Pubitemid 46564068)
11. Hendriks-Balk, M.C., Peters, S.L., Michel, M.C., Alewijnse, A.E. (2008): Regulation of G protein-coupled receptor signalling: Focus on the cardiovascular system and regulator of G protein signalling proteins. Eur J Pharmacol, 585, 278-291.
12. Hernanz, R., Alonso, M.J., Briones, A.M., Vila, E., Simonsen, U., Salaices, M. (2003): Mechanisms involved in the early increase of serotonin contraction evoked by endotoxin in rat middle cerebral arteries. Br J Pharmacol, 140, 671-680. (Pubitemid 37386431)
13. Heximer, S.P., Knutsen, R.H., Sun, X., Kaltenbronn, K.M., Rhee, M.H., Peng, N., Oliveira-dos-Santos, A., Penninger, J.M., Muslin, A.J., Steinberg, T.H., Wyss, J.M., Mecham, R.P., Blumer, K.J. (2003): Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest, 111, 445-452. (Pubitemid 36228001)
14. Hollinger, S., Hepler, J.R. (2002): Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol Rev, 54, 527-559.
15. Ishimaru, S., Shichiri, M., Mineshita, S., Hirata, Y. (2001): Role of endothelin-1/endothelin receptor system in endotoxic shock rats. Hypertens Res, 24, 119-126. (Pubitemid 32377582)
16. Matsuda, N., Hattori, Y. (2007): Vascular biology in sepsis: pathophysiological and therapeutic significance of vascular dysfunction. J Smooth Muscle Res, 43, 117-137.
17. Murray, P.T., Wylam, M.E., Umans, J.G. (2000): Nitric oxide and septic vascular dysfunction. Anesth Analg, 90, 89-101. (Pubitemid 30022977)
18. Opal, S.M. (2007): The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis. Int J Med Microbiol, 297, 365-377. (Pubitemid 47188050)
19. Panetta, R., Guo, Y., Magder, S., Greenwood, M.T. (1999): Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression. Biochem Biophys Res Commun, 259, 550-556. (Pubitemid 29335571)
20. Parrillo, J.E., Parker, M. M., Natanson, C., Suffredini, A.F., Danner, R.L., Cunnion, R.E., Ognibene, F.P. (1990): Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med, 113, 227-242.
21. Patten, M., Bunemann, J., Thoma, B., Kramer, E., Thoenes, M., Stube, S., Mittmann, C., Wieland, T. (2002): Endotoxin induces desensitization of cardiac endothelin-1 receptor signaling by increased expression of RGS4 and RGS16. Cardiovasc Res, 53, 156-164. (Pubitemid 34020776)
22. Ross, E.M., Wilkie, T.M. (2000): GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu Rev Biochem, 69, 795-827. (Pubitemid 30792227)
23. Roth, B.L., Spitzer, J.A. (1987): Altered hepatic vasopressin and alpha 1-adrenergic receptors after chronic endotoxin infusion. Am J Physiol, 252, E699-702.
24. Semplicini, A., Lenzini, L., Sartori, M., Papparella, I., Calo, L. A., Pagnin, E., Strapazzon, G., Benna, C., Costa, R., Avogaro, A., Ceolotto, G., Pessina, A.C. (2006): Reduced expression of regulator of G-protein signaling 2 (RGS2) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II. J Hypertens, 24, 1115-1124. (Pubitemid 43772320)
25. Shuang, C., Wong, M.H., Schulte, D.J., Arditi, M., Michelsen, K.S. (2007): Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells. J Endotoxin Res, 13, 281-296. (Pubitemid 350056224)
26. Siderovski, D.P., Willard, F.S. (2005): The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits. Int J Biol Sci, 1, 51-66.
27. Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., Speleman, F. (2002): Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol, 3, RESEARCH0034.
28. Wieland, T., Lutz, S., Chidiac, P. (2007): Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system. Curr Opin Pharmacol, 7, 201-207. (Pubitemid 46404739)
29. Wieland, T., Mittmann, C. (2003): Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system. Pharmacol Ther, 97, 95-115. (Pubitemid 36136081)
30. Wylam, M.E., Metkus, A. P., Umans, J. G. (2001): Nitric oxide dependent and independent effects of in vitro incubation or endotoxin on vascular reactivity in rat aorta. Life Sci, 69, 455-467. (Pubitemid 32539387)
31. Yang, X., Coriolan, D., Murthy, V., Schultz, K., Golenbock, D. T., Beasley, D. (2005): Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling. Am J Physiol Heart Circ Physiol, 289, H1069-1076. (Pubitemid 41208948)