메뉴 건너뛰기




Volumn 11, Issue 3, 2009, Pages 238-247

Deficient DNA mismatch repair is common in Lynch syndrome-associated colorectal adenomas

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MARKER; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

EID: 67149125977     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.2353/jmoldx.2009.080142     Document Type: Article
Times cited : (84)

References (49)
  • 1
    • 0032730774 scopus 로고    scopus 로고
    • Genetic susceptibility to non-polyposis colorectal cancer
    • Lynch HT, de la Chapelle A: Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet 1999, 36:801-818
    • (1999) J Med Genet , vol.36 , pp. 801-818
    • Lynch, H.T.1    de la Chapelle, A.2
  • 2
    • 0015077284 scopus 로고
    • Cancer family G revisited: 1895-1970
    • Lynch HT, Krush AJ: Cancer family G revisited: 1895-1970. Cancer 1971, 27:1505-1511
    • (1971) Cancer , vol.27 , pp. 1505-1511
    • Lynch, H.T.1    Krush, A.J.2
  • 3
    • 0026088343 scopus 로고
    • Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer)
    • Mecklin JP, Järvinen HJ: Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer). Cancer 1991, 68:1109-1112
    • (1991) Cancer , vol.68 , pp. 1109-1112
    • Mecklin, J.P.1    Järvinen, H.J.2
  • 9
    • 0030882381 scopus 로고    scopus 로고
    • Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer
    • Peltomaki P, Vasen HF: Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. Gastroenterology 1997, 113:1146-1158
    • (1997) Gastroenterology , vol.113 , pp. 1146-1158
    • Peltomaki, P.1    Vasen, H.F.2
  • 12
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993, 363:558-561
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 13
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S: A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998, 58:5248-5252
    • (1998) Cancer Res , vol.58 , pp. 5248-5252
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5    Burt, R.W.6    Meltzer, S.J.7    Rodriguez-Bigas, M.A.8    Fodde, R.9    Ranzani, G.N.10    Srivastava, S.11
  • 14
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau S, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816-819
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.1    Bren, G.2    Schaid, D.3
  • 15
    • 0035054387 scopus 로고    scopus 로고
    • Deficient DNA mismatch repair: A common etiologic factor for colon cancer
    • Peltomaki P: Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Hum Mol Genet 2001, 10:735-740
    • (2001) Hum Mol Genet , vol.10 , pp. 735-740
    • Peltomaki, P.1
  • 16
    • 0033055150 scopus 로고    scopus 로고
    • Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: A study in different groups of patients with colorectal cancer
    • Lamberti C, Kruse R, Ruelfs C, Caspari R, Wang Y, Jungck M, Mathiak M, Malayeri HR, Friedl W, Sauerbruch T, Propping P: Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer. Gut 1999, 44:839-843
    • (1999) Gut , vol.44 , pp. 839-843
    • Lamberti, C.1    Kruse, R.2    Ruelfs, C.3    Caspari, R.4    Wang, Y.5    Jungck, M.6    Mathiak, M.7    Malayeri, H.R.8    Friedl, W.9    Sauerbruch, T.10    Propping, P.11
  • 18
    • 0036070937 scopus 로고    scopus 로고
    • Immunohistochemical pattern of MLH1/MSH2 expression is related to clinical and pathological features in colorectal adenocarcinomas with microsatellite instability
    • Lanza G, Gafà R, Maestri I, Santini A, Matteuzzi M, Cavazzini L: Immunohistochemical pattern of MLH1/MSH2 expression is related to clinical and pathological features in colorectal adenocarcinomas with microsatellite instability. Mod Pathol 2002, 15:741-749
    • (2002) Mod Pathol , vol.15 , pp. 741-749
    • Lanza, G.1    Gafà, R.2    Maestri, I.3    Santini, A.4    Matteuzzi, M.5    Cavazzini, L.6
  • 19
    • 0033943413 scopus 로고    scopus 로고
    • hMLH1 and hMSH2 immunostaining in colorectal cancer
    • Jass JR: hMLH1 and hMSH2 immunostaining in colorectal cancer. Gut 2000, 47:315-316
    • (2000) Gut , vol.47 , pp. 315-316
    • Jass, J.R.1
  • 20
    • 6444245757 scopus 로고    scopus 로고
    • Müller W, Burgart LJ, Krause-Paulus R, Thibodeau SN, Almeida M, Edmonston TB, Boland CR, Sutter C, Jass JR, Lindblom A, Lubinski J, MacDermot K, Sanders DS, Morreau H, Müller A, Oliani C, Orntoft T, Ponz De Leon M, Rosty C, Rodriguez-Bigas M, Rüschoff J, Ruszkiewicz A, Sabourin J, Salovaara R, Möslein G; ICG-HNPCC (International Collaborative Group): The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)-Results of an international collaborative study. Fam Cancer 2001, 1:87-93
    • Müller W, Burgart LJ, Krause-Paulus R, Thibodeau SN, Almeida M, Edmonston TB, Boland CR, Sutter C, Jass JR, Lindblom A, Lubinski J, MacDermot K, Sanders DS, Morreau H, Müller A, Oliani C, Orntoft T, Ponz De Leon M, Rosty C, Rodriguez-Bigas M, Rüschoff J, Ruszkiewicz A, Sabourin J, Salovaara R, Möslein G; ICG-HNPCC (International Collaborative Group): The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)-Results of an international collaborative study. Fam Cancer 2001, 1:87-93
  • 23
    • 0028141683 scopus 로고
    • Hereditary non-polyposis colorectal cancer: Morphologies, genes and mutations
    • Jass JR, Stewart SM, Stewart J, Lane MR: Hereditary non-polyposis colorectal cancer: morphologies, genes and mutations. Mutat Res 1994, 310:125-133
    • (1994) Mutat Res , vol.310 , pp. 125-133
    • Jass, J.R.1    Stewart, S.M.2    Stewart, J.3    Lane, M.R.4
  • 24
    • 0036150916 scopus 로고    scopus 로고
    • Adenoma prevalence and cancer risk in familial non-polyposis colorectal cancer
    • Lindgren G, Liljegren A, Jaramillo E, Rubio C, Lindblom A: Adenoma prevalence and cancer risk in familial non-polyposis colorectal cancer. Gut 2002, 50:228-234
    • (2002) Gut , vol.50 , pp. 228-234
    • Lindgren, G.1    Liljegren, A.2    Jaramillo, E.3    Rubio, C.4    Lindblom, A.5
  • 25
    • 0036182102 scopus 로고    scopus 로고
    • Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation
    • Rijcken FEM, Hollema H, Kleibeuker JH: Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation. Gut 2002, 50:382-386
    • (2002) Gut , vol.50 , pp. 382-386
    • Rijcken, F.E.M.1    Hollema, H.2    Kleibeuker, J.H.3
  • 27
  • 28
    • 0033914750 scopus 로고    scopus 로고
    • DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer
    • Iino H, Simms L, Young J, Arnold J, Winship IM, Webb SI, Furlong KL, Leggett B, Jass JR: DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer. Gut 2000, 47:37-42
    • (2000) Gut , vol.47 , pp. 37-42
    • Iino, H.1    Simms, L.2    Young, J.3    Arnold, J.4    Winship, I.M.5    Webb, S.I.6    Furlong, K.L.7    Leggett, B.8    Jass, J.R.9
  • 30
    • 24044540727 scopus 로고    scopus 로고
    • Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer
    • Halvarsson B, Lindblom A, Johansson L, Lagerstedt K, Nilbert M: Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer. Mod Pathol 2005, 18:1095-1101
    • (2005) Mod Pathol , vol.18 , pp. 1095-1101
    • Halvarsson, B.1    Lindblom, A.2    Johansson, L.3    Lagerstedt, K.4    Nilbert, M.5
  • 33
    • 11144279281 scopus 로고    scopus 로고
    • Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms
    • Shia J, Klimstra DS, Nafa K, Offit K, JG Guillem, Markowitz AJ, Gerald WL, Ellis NA: Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms. Am J Surg Pathol 2005, 29:96-104
    • (2005) Am J Surg Pathol , vol.29 , pp. 96-104
    • Shia, J.1    Klimstra, D.S.2    Nafa, K.3    Offit, K.4    Guillem, J.G.5    Markowitz, A.J.6    Gerald, W.L.7    Ellis, N.A.8
  • 34
    • 20844432697 scopus 로고    scopus 로고
    • Consortium: Microsatellite analysis of hereditary nonpolyposis colorectal cancer-associated colorectal adenomas by laser-assisted microdissection: correlation with mismatch repair protein expression provides new insights in early steps of tumorigenesis
    • Giuffre G, Müller A, Brodegger T, Bocker Edmonston T, Gebert J, Kloor M, Dietmaier W, Kullmann F, Büttner R, Tuccari G, Rüschoff J, German HNPCC Consortium: Microsatellite analysis of hereditary nonpolyposis colorectal cancer-associated colorectal adenomas by laser-assisted microdissection: correlation with mismatch repair protein expression provides new insights in early steps of tumorigenesis. J Mol Diagn 2005, 7:160-170
    • (2005) J Mol Diagn , vol.7 , pp. 160-170
    • Giuffre, G.1    Müller, A.2    Brodegger, T.3    Bocker Edmonston, T.4    Gebert, J.5    Kloor, M.6    Dietmaier, W.7    Kullmann, F.8    Büttner, R.9    Tuccari, G.10    Rüschoff, J.11    German, H.N.P.C.C.12
  • 35
    • 0027145633 scopus 로고    scopus 로고
    • Leacha FS, Nicolaidesa NC, Papadopoulosa N, Bo Liu, Jena J, Parsonsa R, Peltomäkib P, Sistonenb P, Aaltonenb LA, Nyström-Lahtib M, Guanc XY, Zhangc J, Meltzerc PS, Yud J-W, Kaod F-T, Chene DJ, Cerosalettif KM, Fournierf REK, Toddg S, Lewisg T, Leachg RJ, Naylorg SL, Weissenbachh J, Mecklinb J-P, Järvinenb H, Peterseni GM, Hamiltonj SR, Greenk J, Jassl J, Watsonm P, Lynchm HT, Trenta JM, de la Chapelle A, Kinzler KW, Vogelsteina B: Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993, 75:1215-1225
    • Leacha FS, Nicolaidesa NC, Papadopoulosa N, Bo Liu, Jena J, Parsonsa R, Peltomäkib P, Sistonenb P, Aaltonenb LA, Nyström-Lahtib M, Guanc XY, Zhangc J, Meltzerc PS, Yud J-W, Kaod F-T, Chene DJ, Cerosalettif KM, Fournierf REK, Toddg S, Lewisg T, Leachg RJ, Naylorg SL, Weissenbachh J, Mecklinb J-P, Järvinenb H, Peterseni GM, Hamiltonj SR, Greenk J, Jassl J, Watsonm P, Lynchm HT, Trenta JM, de la Chapelle A, Kinzler KW, Vogelsteina B: Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993, 75:1215-1225
  • 38
    • 0037096801 scopus 로고    scopus 로고
    • Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families
    • Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E: Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res 2002, 62:3485-3492
    • (2002) Cancer Res , vol.62 , pp. 3485-3492
    • Wahlberg, S.S.1    Schmeits, J.2    Thomas, G.3    Loda, M.4    Garber, J.5    Syngal, S.6    Kolodner, R.D.7    Fox, E.8
  • 39
    • 0035044718 scopus 로고    scopus 로고
    • Microsatellite Instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer
    • Salahshor S, Koelble K, Rubio C, Lindblom A: Microsatellite Instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer. Lab Invest 2001, 81:535-541
    • (2001) Lab Invest , vol.81 , pp. 535-541
    • Salahshor, S.1    Koelble, K.2    Rubio, C.3    Lindblom, A.4
  • 46
    • 0042941629 scopus 로고    scopus 로고
    • Cancer Genome Project: BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
    • Chan TL, Zhao W, Leung SY, Yuen ST; Cancer Genome Project: BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res 2003, 63:4878-4881
    • (2003) Cancer Res , vol.63 , pp. 4878-4881
    • Chan, T.L.1    Zhao, W.2    Leung, S.Y.3    Yuen, S.T.4
  • 47
    • 0000441155 scopus 로고    scopus 로고
    • DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutator pathway for colorectal cancer?
    • Iino H, Jass JR, Simms LA, Young J, Leggett B, Ajioka Y, Watanabe H: DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? J Clin Pathol 1999, 52:5-9
    • (1999) J Clin Pathol , vol.52 , pp. 5-9
    • Iino, H.1    Jass, J.R.2    Simms, L.A.3    Young, J.4    Leggett, B.5    Ajioka, Y.6    Watanabe, H.7
  • 48
    • 0030936767 scopus 로고    scopus 로고
    • Mixed epithelial polyps in association with hereditary non-polyposis colorectal cancer providing an alternative pathway of cancer histogenesis
    • Jass JR, Cottier DS, Pokos V, Parry S, Winship IM: Mixed epithelial polyps in association with hereditary non-polyposis colorectal cancer providing an alternative pathway of cancer histogenesis. Pathology 1997, 29:28-33
    • (1997) Pathology , vol.29 , pp. 28-33
    • Jass, J.R.1    Cottier, D.S.2    Pokos, V.3    Parry, S.4    Winship, I.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.