-
1
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong JA, Tapia-RamiRez J, Kim S et al.: REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957 (1995).
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
Tapia-RamiRez, J.2
Kim, S.3
-
2
-
-
0028968802
-
The neuron-restrictive silencer factor (NRSF): A coordinate represser of multiple neuron-specific genes
-
Schoenherr CJ, Anderson DJ: The neuron-restrictive silencer factor (NRSF): a coordinate represser of multiple neuron-specific genes. Science 267, 1360-1363 (1995).
-
(1995)
Science
, vol.267
, pp. 1360-1363
-
-
Schoenherr, C.J.1
Anderson, D.J.2
-
3
-
-
0031694917
-
NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
-
Chen ZF, Paquette AJ, Anderson DJ: NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat. Genet. 20, 136-142 (1998).
-
(1998)
Nat. Genet
, vol.20
, pp. 136-142
-
-
Chen, Z.F.1
Paquette, A.J.2
Anderson, D.J.3
-
4
-
-
0000385942
-
Neurological disease: Listening to gene silencers
-
Roopra A, Huang Y, Dingledine R: Neurological disease: listening to gene silencers. Mol. Interv. 1, 219-228 (2001).
-
(2001)
Mol. Interv
, vol.1
, pp. 219-228
-
-
Roopra, A.1
Huang, Y.2
Dingledine, R.3
-
5
-
-
25844518743
-
The many faces of REST oversee epigenetic programming of neuronal genes
-
Ballas N, Mandel G: The many faces of REST oversee epigenetic programming of neuronal genes. Curr. Opin. Neurobiol. 15, 500-506 (2005).
-
(2005)
Curr. Opin. Neurobiol
, vol.15
, pp. 500-506
-
-
Ballas, N.1
Mandel, G.2
-
6
-
-
24044505984
-
Transcriptional regulation: Cancer, neurons and the REST
-
Coulson JM: Transcriptional regulation: cancer, neurons and the REST. Curr. Biol. 15, R665-R668 (2005).
-
(2005)
Curr. Biol
, vol.15
-
-
Coulson, J.M.1
-
7
-
-
27544454705
-
Chromatin remodeling in neural development and plasticity
-
Hsieh J, Gage FH: Chromatin remodeling in neural development and plasticity. Curr. Opin. Cell. Biol. 17, 1-8 (2005).
-
(2005)
Curr. Opin. Cell. Biol
, vol.17
, pp. 1-8
-
-
Hsieh, J.1
Gage, F.H.2
-
8
-
-
19344372003
-
No rest for REST: REST/NRSF regulation of neurogenesis
-
Lunyak VV, Rosenfeld MG: No rest for REST: REST/NRSF regulation of neurogenesis. Cell 121, 499-501 (2005).
-
(2005)
Cell
, vol.121
, pp. 499-501
-
-
Lunyak, V.V.1
Rosenfeld, M.G.2
-
9
-
-
33748921564
-
REST in good times and bad: Roles in tumor suppressor and oncogenic activities
-
Majumder S: REST in good times and bad: roles in tumor suppressor and oncogenic activities. Cell Cycle 5, 1929-1935 (2006).
-
(2006)
Cell Cycle
, vol.5
, pp. 1929-1935
-
-
Majumder, S.1
-
10
-
-
33745602880
-
Noncoding RNAs in the mammalian central nervous system
-
Cao X, Yeo G, Muotri AR et al.: Noncoding RNAs in the mammalian central nervous system. Annu. Rev. Neurosci. 29, 77-103 (2006).
-
(2006)
Annu. Rev. Neurosci
, vol.29
, pp. 77-103
-
-
Cao, X.1
Yeo, G.2
Muotri, A.R.3
-
11
-
-
34250767817
-
Chromatin crosstalk in development and disease: Lessons from REST
-
Ooi L, Wood IC: Chromatin crosstalk in development and disease: lessons from REST. Nat. Rev. Genet. 8, 544-554 (2007).
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 544-554
-
-
Ooi, L.1
Wood, I.C.2
-
12
-
-
42949162122
-
How much REST is enough?
-
Weissman A: How much REST is enough? Cancer Cell 13, 381-383 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 381-383
-
-
Weissman, A.1
-
13
-
-
52449109154
-
Regulation of gene expression in the nervous system
-
Ooi L, Wood IC: Regulation of gene expression in the nervous system. Biochem. J. 414, 327-341 (2008).
-
(2008)
Biochem. J
, vol.414
, pp. 327-341
-
-
Ooi, L.1
Wood, I.C.2
-
14
-
-
54949091162
-
Stem Cells have different needs for REST
-
Hermanson O: Stem Cells have different needs for REST. PLoS Biol. 6, 2094-2097 (2008).
-
(2008)
PLoS Biol
, vol.6
, pp. 2094-2097
-
-
Hermanson, O.1
-
15
-
-
0026659651
-
Silencing the type II sodium channel gene: A model for neural-specific gene regulation
-
Kraner SD, Chong JA, Tsay HJ, Mandel G: Silencing the type II sodium channel gene: a model for neural-specific gene regulation. Neuron 9, 37-44 (1992).
-
(1992)
Neuron
, vol.9
, pp. 37-44
-
-
Kraner, S.D.1
Chong, J.A.2
Tsay, H.J.3
Mandel, G.4
-
16
-
-
3142764484
-
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes
-
Bruce AW, Donaldson IJ, Wood IC et al.: Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc. Natl Acad. Sci. USA 101, 10458-10463 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10458-10463
-
-
Bruce, A.W.1
Donaldson, I.J.2
Wood, I.C.3
-
17
-
-
33748526495
-
Identification of REST regulon reveals extensive transposable element-mediated binding site duplication
-
Johnson R, Gamblin RJ, Ooi L et al.: Identification of REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res. 34, 3862-3877 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3862-3877
-
-
Johnson, R.1
Gamblin, R.J.2
Ooi, L.3
-
18
-
-
34250815056
-
A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions
-
Otto SJ, McCorkle SR, Hover J et al.: A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. J. Neurosci. 27, 6729-6739 (2007).
-
(2007)
J. Neurosci
, vol.27
, pp. 6729-6739
-
-
Otto, S.J.1
McCorkle, S.R.2
Hover, J.3
-
19
-
-
34250159524
-
Genome-wide mapping of in vivo protein DNA interactions
-
Johnson DS, Mortazavi A, Myers RM et al.: Genome-wide mapping of in vivo protein DNA interactions. Science 316, 1497-1502 (2007).
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
-
20
-
-
33144481470
-
Reciprocal actions of REST and a microRNA promote neuronal identity
-
Conaco C, Otto S, Han JJ et al.: Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl Acad. Sci. USA 103, 2422-2427 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2422-2427
-
-
Conaco, C.1
Otto, S.2
Han, J.J.3
-
21
-
-
34147157651
-
The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
-
Visvanathan J, Le S, Le B et al.: The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749 (2006).
-
(2006)
Genes Dev
, vol.21
, pp. 744-749
-
-
Visvanathan, J.1
Le, S.2
Le, B.3
-
22
-
-
33750432857
-
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression
-
Wu J and Xie X: Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol. 7, R85 (2007).
-
(2007)
Genome Biol
, vol.7
-
-
Wu, J.1
Xie, X.2
-
23
-
-
33749389932
-
Comparative genomics modeling of the NRSF/REST network: From single conserved sites to genome-wide repertoire
-
Mortazavi A, Leeper Thompson EC et al.: Comparative genomics modeling of the NRSF/REST network: from single conserved sites to genome-wide repertoire. Genome Res. 16, 1208-1221 (2006).
-
(2006)
Genome Res
, vol.16
, pp. 1208-1221
-
-
Mortazavi, A.1
Leeper Thompson, E.C.2
-
24
-
-
52649132425
-
Genome-wide identification of in vivo protein DNA binding sites from ChIP-Seq data
-
Jothi R, Cuddapah S, Barski A et al.: Genome-wide identification of in vivo protein DNA binding sites from ChIP-Seq data. Nucleic Acids Res. 36, 5221-5231 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 5221-5231
-
-
Jothi, R.1
Cuddapah, S.2
Barski, A.3
-
25
-
-
28644440340
-
Distinct profiles of REST interaction with its target genes at different stages of neuronal development
-
Sun YM, Greenway DJ, Johnson R et al.: Distinct profiles of REST interaction with its target genes at different stages of neuronal development. Mol. Cell. Biol. 16, 5630-5638 (2005).
-
(2005)
Mol. Cell. Biol
, vol.16
, pp. 5630-5638
-
-
Sun, Y.M.1
Greenway, D.J.2
Johnson, R.3
-
26
-
-
33846936237
-
RE1 silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells
-
Greenway DJ, Street M, Jeffries A, Buckley NJ: RE1 silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells. Stem Cells 25, 354-363 (2007).
-
(2007)
Stem Cells
, vol.25
, pp. 354-363
-
-
Greenway, D.J.1
Street, M.2
Jeffries, A.3
Buckley, N.J.4
-
27
-
-
54949103985
-
REST regulates distinct transcriptional networks in embryonic and neural stem cells
-
Johnson R, Teh CH-L, Kunarso G et al.: REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol. 6, 2205-2219 (2008).
-
(2008)
PLoS Biol
, vol.6
, pp. 2205-2219
-
-
Johnson, R.1
Teh, C.H.-L.2
Kunarso, G.3
-
28
-
-
56349138235
-
REST-mediated regulation of extracellular matrix is crucial for neural development
-
Sun YM, Cooper M, Finch S et al.: REST-mediated regulation of extracellular matrix is crucial for neural development. PLoS ONE 3, E3656 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Sun, Y.M.1
Cooper, M.2
Finch, S.3
-
29
-
-
58149103424
-
Regulation of neural macroRNAs by the transcriptional repressor REST
-
Johnson R, Teh CH, Jia H et al.: Regulation of neural macroRNAs by the transcriptional repressor REST. RNA 15, 85-96 (2009).
-
(2009)
RNA
, vol.15
, pp. 85-96
-
-
Johnson, R.1
Teh, C.H.2
Jia, H.3
-
30
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato C, Tartari M, Crotti A et al.: Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 35, 76-83 (2003).
-
(2003)
Nat. Genet
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
-
31
-
-
34347364706
-
Widespread disruption of repressor element-1 silencing transcription factor/neuron restrictive silencer factor occupancy at its target genes in Huntington's disease
-
Zuccato C, Belyaev N, Conforti P et al.: Widespread disruption of repressor element-1 silencing transcription factor/neuron restrictive silencer factor occupancy at its target genes in Huntington's disease. J. Neurosci. 27, 6972-6983 (2007).
-
(2007)
J. Neurosci
, vol.27
, pp. 6972-6983
-
-
Zuccato, C.1
Belyaev, N.2
Conforti, P.3
-
32
-
-
39649092720
-
A microRNA-based gene dysregulation pathway in Huntington's disease
-
Johnson R, Zuccato C, Belyaev ND et al.: A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol. Dis. 29, 438-445 (2008).
-
(2008)
Neurobiol. Dis
, vol.29
, pp. 438-445
-
-
Johnson, R.1
Zuccato, C.2
Belyaev, N.D.3
-
33
-
-
21744435291
-
Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons
-
Qiang M, Rani CS, Ticku MK: Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons. Mol. Pharmacol. 67, 2115-2125 (2005).
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 2115-2125
-
-
Qiang, M.1
Rani, C.S.2
Ticku, M.K.3
-
34
-
-
25844523898
-
Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation
-
Cheong A, Bingham AJ, Li J et al.: Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol. Cell 20, 45-52 (2005).
-
(2005)
Mol. Cell
, vol.20
, pp. 45-52
-
-
Cheong, A.1
Bingham, A.J.2
Li, J.3
-
35
-
-
33750731643
-
Regulatory role of neuron-restrictive silencing factor in the expression of TRPC1
-
Ohba T, Watanabe H, Takahashi Y et al.: Regulatory role of neuron-restrictive silencing factor in the expression of TRPC1. Biochem. Biophys. Res. Commun. 351, 764-770 (2006).
-
(2006)
Biochem. Biophys. Res. Commun
, vol.351
, pp. 764-770
-
-
Ohba, T.1
Watanabe, H.2
Takahashi, Y.3
-
36
-
-
33751349707
-
Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes
-
Nakagawa Y, Kuwahara K, Harada M et al.: Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes. J. Mol. Cell. Cardiol. 41, 1010-1022 (2006).
-
(2006)
J. Mol. Cell. Cardiol
, vol.41
, pp. 1010-1022
-
-
Nakagawa, Y.1
Kuwahara, K.2
Harada, M.3
-
37
-
-
33845629427
-
NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes
-
Kuratomi S, Kuratomi A, Kuwahara K et al.: NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes. Biochem. Biophys. Res. Commun. 353, 67-73 (2007).
-
(2007)
Biochem. Biophys. Res. Commun
, vol.353
, pp. 67-73
-
-
Kuratomi, S.1
Kuratomi, A.2
Kuwahara, K.3
-
38
-
-
59149096820
-
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression
-
Ding N, Tommori-Sato C, Sato S et al.: MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. J. Biol. Chem. 284, 2648-2656 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 2648-2656
-
-
Ding, N.1
Tommori-Sato, C.2
Sato, S.3
-
39
-
-
0037444555
-
Ischemic insults derepress the gene silencer REST in neurons destined to die
-
Calderone A, Jover T, Noh KM et al.: Ischemic insults derepress the gene silencer REST in neurons destined to die. J. Neurosci. 23, 2112-2121 (2003).
-
(2003)
J. Neurosci
, vol.23
, pp. 2112-2121
-
-
Calderone, A.1
Jover, T.2
Noh, K.M.3
-
40
-
-
33750443292
-
2-deoxy- D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure
-
Garriga-Canut M, Scoenike B, Qazi R et al.: 2-deoxy- D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure. Nat. Neurosci. 9, 1382-1387 (2006).
-
(2006)
Nat. Neurosci
, vol.9
, pp. 1382-1387
-
-
Garriga-Canut, M.1
Scoenike, B.2
Qazi, R.3
-
41
-
-
34247185756
-
Ischemic insults promote epigenetic reprogramming of μ opioid receptor expression in hippocampal neurons
-
Formisano L, Noh KM, Miyawaki T et al.: Ischemic insults promote epigenetic reprogramming of μ opioid receptor expression in hippocampal neurons. Proc. Natl Acad. Sci. USA 104, 4170-4175 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 4170-4175
-
-
Formisano, L.1
Noh, K.M.2
Miyawaki, T.3
-
42
-
-
32044465194
-
Implication of increased NRSF/REST binding activity in the mechanism of ethanol inhibition of neuronal differentiation
-
Tateno M, Ukai W, Hashimoto E et al.: Implication of increased NRSF/REST binding activity in the mechanism of ethanol inhibition of neuronal differentiation. J. Neural Transm. 113, 283-293 (2006).
-
(2006)
J. Neural Transm
, vol.113
, pp. 283-293
-
-
Tateno, M.1
Ukai, W.2
Hashimoto, E.3
-
43
-
-
49749131540
-
Lithium induced suppression of transcription factor NRSF/REST: Effects on the dysfunction of neuronal differentiation by ethanol
-
Ishii T, Hashimoto E, Ukai W et al.: Lithium induced suppression of transcription factor NRSF/REST: effects on the dysfunction of neuronal differentiation by ethanol. Eur. J. Pharmacol. 593, 36-43 (2008).
-
(2008)
Eur. J. Pharmacol
, vol.593
, pp. 36-43
-
-
Ishii, T.1
Hashimoto, E.2
Ukai, W.3
-
44
-
-
34848916457
-
Regulation of tryptophan hydroxylase-2 gene expression by a bi-partite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif
-
Patel PD, Bochar DA, Turner DL et al.: Regulation of tryptophan hydroxylase-2 gene expression by a bi-partite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif. J. Biol. Chem. 282, 26717-26724 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 26717-26724
-
-
Patel, P.D.1
Bochar, D.A.2
Turner, D.L.3
-
45
-
-
48249123167
-
Regulatory role of neuron-restrictive silencing factor in the specific expression of cocaine- and amphetamine-regulated transcript gene
-
Li Y, Liu Q, Yang Y et al.: Regulatory role of neuron-restrictive silencing factor in the specific expression of cocaine- and amphetamine-regulated transcript gene. J. Neurochem. 106, 1314-1324 (2008).
-
(2008)
J. Neurochem
, vol.106
, pp. 1314-1324
-
-
Li, Y.1
Liu, Q.2
Yang, Y.3
-
46
-
-
35348870927
-
Targets of neuron-restrictive silencing factor are abnormally up-regulated in human myotilinopathy
-
Barrachina M, Moreno J, Juves S, Moreno D, Olive M, Ferrer I: Targets of neuron-restrictive silencing factor are abnormally up-regulated in human myotilinopathy. Am. J. Pathol. 171, 1312-1323 (2007).
-
(2007)
Am. J. Pathol
, vol.171
, pp. 1312-1323
-
-
Barrachina, M.1
Moreno, J.2
Juves, S.3
Moreno, D.4
Olive, M.5
Ferrer, I.6
-
47
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
Lee MG, Wynder C, Cooch N et al.: An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437, 432-435 (2005).
-
(2005)
Nature
, vol.437
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
-
48
-
-
12844250536
-
Small CTD phosphatases function in silencing neuronal gene expression
-
Yeo M, Lee SK, Lee B et al.: Small CTD phosphatases function in silencing neuronal gene expression. Science 307, 596-600 (2005).
-
(2005)
Science
, vol.307
, pp. 596-600
-
-
Yeo, M.1
Lee, S.K.2
Lee, B.3
-
49
-
-
30944436854
-
SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines
-
Watanabe H, Mizutani T, Haraguchi T et al.: SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines. Oncogene 25, 470-479 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 470-479
-
-
Watanabe, H.1
Mizutani, T.2
Haraguchi, T.3
-
50
-
-
33947302685
-
The X-linked mental retardation gene SMCX/JARID1 defines a family of histone H3 lysine 4 demethylases
-
Iwase S, Lan F, Bayliss P et al.: The X-linked mental retardation gene SMCX/JARID1 defines a family of histone H3 lysine 4 demethylases. Cell 128, 1077-1088 (2007).
-
(2007)
Cell
, vol.128
, pp. 1077-1088
-
-
Iwase, S.1
Lan, F.2
Bayliss, P.3
-
51
-
-
34249900454
-
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
-
Tahiliani M, Mei P, Fang R et al.: The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 447, 601-605 (2007).
-
(2007)
Nature
, vol.447
, pp. 601-605
-
-
Tahiliani, M.1
Mei, P.2
Fang, R.3
-
52
-
-
48349122949
-
Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation
-
Ding N, Zhou H, Esteve PO et al.: Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation. Mol. Cell 3, 347-359 (2008).
-
(2008)
Mol. Cell
, vol.3
, pp. 347-359
-
-
Ding, N.1
Zhou, H.2
Esteve, P.O.3
-
53
-
-
57049167675
-
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation
-
Mulligan P, Westbrook TF, Ottinger M et al.: CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol. Cell 32, 718-726 (2008).
-
(2008)
Mol. Cell
, vol.32
, pp. 718-726
-
-
Mulligan, P.1
Westbrook, T.F.2
Ottinger, M.3
-
54
-
-
53249087743
-
Non-telomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells
-
Zhang P, Pazin M, Schwartz CM et al.: Non-telomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells. Curr. Biol. 18, 1489-1494 (2008).
-
(2008)
Curr. Biol
, vol.18
, pp. 1489-1494
-
-
Zhang, P.1
Pazin, M.2
Schwartz, C.M.3
-
55
-
-
55049083176
-
A homozygous mutation in PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy - ataxia syndrome
-
Bassuk AG, Wallace RH, Buhr A et al.: A homozygous mutation in PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy - ataxia syndrome. Am. J. Hum. Genet. 83, 572-581 (2008).
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 572-581
-
-
Bassuk, A.G.1
Wallace, R.H.2
Buhr, A.3
-
56
-
-
0345491828
-
REST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptor
-
Shimojo M, Hersh LB: REST/NRSF-interacting LIM domain protein, a putative nuclear translocation receptor. Mol. Cell. Biol. 23, 9025-9031 (2003).
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 9025-9031
-
-
Shimojo, M.1
Hersh, L.B.2
-
57
-
-
58049197863
-
Huntingtin regulates repressor element-1 silencing transcription factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain interacting protein (RILP) and dynactin p150Glued
-
Shimojo M: Huntingtin regulates repressor element-1 silencing transcription factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain interacting protein (RILP) and dynactin p150Glued. J. Biol. Chem. 283, 34880-34886 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 34880-34886
-
-
Shimojo, M.1
-
58
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert J, Epping M, Pollack R et al.: A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev. Biol. 2, 8-15 (2002).
-
(2002)
BMC Dev. Biol
, vol.2
, pp. 8-15
-
-
Willert, J.1
Epping, M.2
Pollack, R.3
-
59
-
-
0142059234
-
The canonical Wnt pathway directly regulates NRSF/REST expression in chick spinal cord
-
Nishihara S, Tsuda L, Ogura T: The canonical Wnt pathway directly regulates NRSF/REST expression in chick spinal cord. Biochem. Biophys. Res. Commun. 311, 55-63 (2003).
-
(2003)
Biochem. Biophys. Res. Commun
, vol.311
, pp. 55-63
-
-
Nishihara, S.1
Tsuda, L.2
Ogura, T.3
-
60
-
-
19344378337
-
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
-
Ballas N, Grunseich C, Lu D et al.: REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121, 645-657 (2005).
-
(2005)
Cell
, vol.121
, pp. 645-657
-
-
Ballas, N.1
Grunseich, C.2
Lu, D.3
-
61
-
-
41149119961
-
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
-
Westbrook TF, Hu G, Ang XL et al.: SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature 452, 370-374 (2008).
-
(2008)
Nature
, vol.452
, pp. 370-374
-
-
Westbrook, T.F.1
Hu, G.2
Ang, X.L.3
-
62
-
-
1642603947
-
A small modulatory dsRNA specifies the fate of adult neural stem cells
-
Kuwabara T, Hsieh J, Nakashima K et al.: A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 116, 779-793 (2004).
-
(2004)
Cell
, vol.116
, pp. 779-793
-
-
Kuwabara, T.1
Hsieh, J.2
Nakashima, K.3
-
63
-
-
38049132607
-
Dual role of NRSF/REST in activation and repression of the glucocorticoid response
-
Abramovitz L, Shapira T, Ben-Dror I et al.: Dual role of NRSF/REST in activation and repression of the glucocorticoid response. J. Biol. Chem. 283, 110-119 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 110-119
-
-
Abramovitz, L.1
Shapira, T.2
Ben-Dror, I.3
-
64
-
-
41149130221
-
Control of chromosome stability by the β-TrCP-REST-Mad2 axis
-
Guardavaccaro D, Frescas D, Dorrello NV et al.: Control of chromosome stability by the β-TrCP-REST-Mad2 axis. Nature 452, 365-369 (2008).
-
(2008)
Nature
, vol.452
, pp. 365-369
-
-
Guardavaccaro, D.1
Frescas, D.2
Dorrello, N.V.3
-
65
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook TF, Martin ES, Schlabach MR et al.: A genetic screen for candidate tumor suppressors identifies REST. Cell 121, 837-848 (2005).
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
-
66
-
-
0033942317
-
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
-
Lawinger P, Venugopal R, Guo ZS et al.: The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat. Med. 6, 826-831 (2000).
-
(2000)
Nat. Med
, vol.6
, pp. 826-831
-
-
Lawinger, P.1
Venugopal, R.2
Guo, Z.S.3
-
67
-
-
15944374306
-
Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/ neuron-restrictive silencer factor (NRSF), which can be functionally countered by REST-VP16
-
Fuller GN, Su X, Price RE et al.: Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/ neuron-restrictive silencer factor (NRSF), which can be functionally countered by REST-VP16. Mol. J. Cancer Ther. 4, 343-349 (2005).
-
(2005)
Mol. J. Cancer Ther
, vol.4
, pp. 343-349
-
-
Fuller, G.N.1
Su, X.2
Price, R.E.3
-
68
-
-
33644518372
-
Abnormal expression of REST/NRSF and Myc in neural stem/progeniror cells causes cerebellar tumors by blocking neuronal differentiation
-
Su X, Gopalakrishnan V, Stearns D et al.: Abnormal expression of REST/NRSF and Myc in neural stem/progeniror cells causes cerebellar tumors by blocking neuronal differentiation. Mol. Cell. Biol. 26, 1666-1678 (2006).
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 1666-1678
-
-
Su, X.1
Gopalakrishnan, V.2
Stearns, D.3
-
69
-
-
0034710902
-
Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo
-
Paquette AJ, Perez SE, Anderson DJ: Constitutive expression of the neuron-restrictive silencer factor (NRSF)/REST in differentiating neurons disrupts neuronal gene expression and causes axon pathfinding errors in vivo. Proc. Natl Acad. Sci. USA 97, 12318-12323 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 12318-12323
-
-
Paquette, A.J.1
Perez, S.E.2
Anderson, D.J.3
-
70
-
-
23444457449
-
Morphing into cancer: The role of developmental signaling pathways in brain tumor formation
-
Fogarty MP, Kessler JD, Wechsler-Reya RJ: Morphing into cancer: the role of developmental signaling pathways in brain tumor formation. J. Neurobiol. 64, 458-475 (2005).
-
(2005)
J. Neurobiol
, vol.64
, pp. 458-475
-
-
Fogarty, M.P.1
Kessler, J.D.2
Wechsler-Reya, R.J.3
-
71
-
-
58149279841
-
MicroRNA profiling in human medulloblastoma
-
Ferretti E, De Smaele E, Po A et al.: MicroRNA profiling in human medulloblastoma Int. J. Cancer 124, 568-577 (2009)
-
(2009)
Int. J. Cancer
, vol.124
, pp. 568-577
-
-
Ferretti, E.1
De Smaele, E.2
Po, A.3
-
72
-
-
0034284426
-
REST-VP16 activates multiple neuronal differentiation genes in human NT2 cells
-
Immaneni A, Lawinger P, Zhao Z et al.: REST-VP16 activates multiple neuronal differentiation genes in human NT2 cells. Nucleic Acids Res. 28, 3403-3410 (2000).
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 3403-3410
-
-
Immaneni, A.1
Lawinger, P.2
Zhao, Z.3
-
73
-
-
4444220683
-
Activation of REST/NRSF target genes in neural stem cells is sufficient to cause neuronal differentiation
-
Su X, Kameoka S, Lentz S et al.: Activation of REST/NRSF target genes in neural stem cells is sufficient to cause neuronal differentiation. Mol. Cell. Biol. 24, 8018-8025 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 8018-8025
-
-
Su, X.1
Kameoka, S.2
Lentz, S.3
-
74
-
-
1942466502
-
Conversion of myoblasts to physiologically active neuronal phenotype
-
Watanabe Y, Kameoka S, Gopalakrishnan V et al.: Conversion of myoblasts to physiologically active neuronal phenotype. Genes Dev. 18, 889-900 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 889-900
-
-
Watanabe, Y.1
Kameoka, S.2
Gopalakrishnan, V.3
-
75
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Shi Y, Desponts C, Do JT et al.: Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3, 568-574 (2008).
-
(2008)
Cell Stem Cell
, vol.3
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
-
76
-
-
50149108172
-
The promise of human induced pluripotent stem cells for research and therapy
-
Nishikawa S, Goldstein RA, Nierras CR et al.: The promise of human induced pluripotent stem cells for research and therapy. Nat. Rev. Mol. Cell. Biol. 9, 725-729 (2008).
-
(2008)
Nat. Rev. Mol. Cell. Biol
, vol.9
, pp. 725-729
-
-
Nishikawa, S.1
Goldstein, R.A.2
Nierras, C.R.3
-
77
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts
-
Huangfu D, Osafune K, Maehr R et al.: Induction of pluripotent stem cells from primary human fibroblasts. Nat. Biotech. 26, 1269-1275 (2008).
-
(2008)
Nat. Biotech
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
-
78
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang J, Rao S, Chu J et al.: A protein interaction network for pluripotency of embryonic stem cells. Nature 444, 364-368 (2006).
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
-
79
-
-
33847076246
-
Genetic and epigenetic regulators of pluripotency
-
Surani MA, Hayashi K, Hajkova P: Genetic and epigenetic regulators of pluripotency. Cell 128, 747-762 (2007).
-
(2007)
Cell
, vol.128
, pp. 747-762
-
-
Surani, M.A.1
Hayashi, K.2
Hajkova, P.3
-
80
-
-
40749104852
-
An extended network for pluripotency of embryonic stem cells
-
Kim J, Chu J, Shen X et al.: An extended network for pluripotency of embryonic stem cells. Cell 132, 1049-1061 (2008).
-
(2008)
Cell
, vol.132
, pp. 1049-1061
-
-
Kim, J.1
Chu, J.2
Shen, X.3
-
81
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch R, Young R: Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582 (2008).
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
82
-
-
41949134533
-
Generation of pluripotent stem cells from adult mouse liver and stomach cells
-
Aoi T, Yae K, Nakagawa M et al.: Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321, 699-702 (2008).
-
(2008)
Science
, vol.321
, pp. 699-702
-
-
Aoi, T.1
Yae, K.2
Nakagawa, M.3
-
83
-
-
48749109823
-
Pluripotent stem cell lines
-
Yu J, Thomson JA: Pluripotent stem cell lines. Genes Dev. 22, 1987-1997 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 1987-1997
-
-
Yu, J.1
Thomson, J.A.2
-
85
-
-
43449100341
-
REST maintains serf-renewal and pluripotency of embryonic stem cells
-
Singh SK, Kagalwala MN, Perker-Thornburg J et al.: REST maintains serf-renewal and pluripotency of embryonic stem cells. Nature. 453, 223-227 (2008).
-
(2008)
Nature
, vol.453
, pp. 223-227
-
-
Singh, S.K.1
Kagalwala, M.N.2
Perker-Thornburg, J.3
-
87
-
-
62549095522
-
Swi/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells
-
DOI: 10.1634/stemcells.2008-0710
-
Kidder BL, Palmer S, Knott JG: Swi/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. Stem Cells DOI: 10.1634/stemcells.2008-0710 (2008).
-
(2008)
Stem Cells
-
-
Kidder, B.L.1
Palmer, S.2
Knott, J.G.3
-
89
-
-
51149115754
-
DYRK1-A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic cell fate in Down syndrome
-
Canzonetta C, Mulligan C, Deutsch S et al.: DYRK1-A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic cell fate in Down syndrome. Am. J. Hum. Genet. 83, 388-400 (2008).
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 388-400
-
-
Canzonetta, C.1
Mulligan, C.2
Deutsch, S.3
-
90
-
-
33748350491
-
A repressor complex AP4, transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells
-
Kim MY, Jeong BC, Lee JH et al.: A repressor complex AP4, transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. Proc. Natl Acad. Sci. USA 103, 13074-13079 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 13074-13079
-
-
Kim, M.Y.1
Jeong, B.C.2
Lee, J.H.3
-
91
-
-
38049041930
-
An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells
-
Carter MG, Stagg CA, Falco G et al.: An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells. Gene Expr. Patterns 8, 181-198 (2008).
-
(2008)
Gene Expr. Patterns
, vol.8
, pp. 181-198
-
-
Carter, M.G.1
Stagg, C.A.2
Falco, G.3
-
92
-
-
0037176537
-
Neuronal target genes of the neuron restrictive silencer factor in neurospheres derived from fetuses with Down syndrome: A gene expression study
-
Bahn S, Mimmack M, Ryan M et al.: Neuronal target genes of the neuron restrictive silencer factor in neurospheres derived from fetuses with Down syndrome: a gene expression study. Lancet 359, 310-315 (2002).
-
(2002)
Lancet
, vol.359
, pp. 310-315
-
-
Bahn, S.1
Mimmack, M.2
Ryan, M.3
-
93
-
-
1542614449
-
Transcription factor REST-dependent proteins are comparable between Down syndrome and normal brains: Challenging a hypothesis
-
Sohn SY, Weitzdoerfer R, Mori N, Lubeg G: Transcription factor REST-dependent proteins are comparable between Down syndrome and normal brains: challenging a hypothesis. J. Neural Transm. Suppl. 67, 59-66 (2003).
-
(2003)
J. Neural Transm. Suppl
, vol.67
, pp. 59-66
-
-
Sohn, S.Y.1
Weitzdoerfer, R.2
Mori, N.3
Lubeg, G.4
-
94
-
-
43749108844
-
SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease
-
Leone S, Mutti C, Kazantsev A et al.: SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease. Bioorg. Med. Chem. 16, 5695-5703 (2008).
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 5695-5703
-
-
Leone, S.1
Mutti, C.2
Kazantsev, A.3
|