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Volumn 85, Issue 6, 2009, Pages 1015-1026

Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: Heme oxygenase-1-derived normalization of hepatic inflammatory responses

Author keywords

Estrus cycle; HO 1 inhibitor; Liver damage; Ovariectomy; PI3K Akt inhibitor

Indexed keywords

CASPASE 3; CHEMOATTRACTANT; CHROMIUM MESOPORPHYRIN IX CHLORIDE; CYTOKINE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTOPORPHYRIN ZINC; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WORTMANNIN; DNA; ESTROGEN RECEPTOR; GLUTATHIONE TRANSFERASE; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PEROXIDASE;

EID: 67149083230     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0508288     Document Type: Article
Times cited : (14)

References (59)
  • 1
    • 0036849173 scopus 로고    scopus 로고
    • Gender differences in long-term posttraumatic stress disorder outcomes after major trauma: Women are at higher risk of adverse outcomes than men
    • Holbrook, T. L., Hoyt, D. B., Stein, M. B., Sieber, W. J. (2002) Gender differences in long-term posttraumatic stress disorder outcomes after major trauma: women are at higher risk of adverse outcomes than men. J. Trauma 53, 882-888.
    • (2002) J. Trauma , vol.53 , pp. 882-888
    • Holbrook, T.L.1    Hoyt, D.B.2    Stein, M.B.3    Sieber, W.J.4
  • 3
    • 0345492039 scopus 로고    scopus 로고
    • Sex Differences in Hepatic Heme Oxygenase Expression and Activity Following Trauma and Hemorrhagic Shock
    • DOI 10.1001/archsurg.138.12.1375
    • Toth, B., Yokoyama, Y., Kuebler, J. F., Schwacha, M. G., Rue III, L. W., Bland, K. I., Chaudry, I. H. (2003) Sex differences in hepatic heme oxygenase expression and activity following trauma and hemorrhagic shock. Arch. Surg. 138, 1375-1382. (Pubitemid 37499400)
    • (2003) Archives of Surgery , vol.138 , Issue.12 , pp. 1375-1382
    • Toth, B.1    Yokoyama, Y.2    Kuebler, J.F.3    Schwacha, M.G.4    Rue III, L.W.5    Bland, K.I.6    Chaudry, I.H.7
  • 4
    • 33646446976 scopus 로고    scopus 로고
    • Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: Up-regulation of estrogen receptor-β-dependent HO-1
    • DOI 10.1189/jlb.0705363
    • Yu, H. P., Choudhry, M. A., Shimizu, T., Hsieh, Y. C., Schwacha, M. G., Yang, S., Chaudry, I. H. (2006) Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{β}-dependent HO-1. J. Leukoc. Biol. 79, 277-284. (Pubitemid 44831159)
    • (2006) Journal of Leukocyte Biology , vol.79 , Issue.2 , pp. 277-284
    • Yu, H.-P.1    Choudhry, M.A.2    Shimizu, T.3    Hsieh, Y.-C.4    Schwacha, M.G.5    Yang, S.6    Chaudry, I.H.7
  • 5
    • 0030922247 scopus 로고    scopus 로고
    • Repression of interleukin-6 gene expression by 17β-estradiol: Inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-κ B by the estrogen receptor
    • DOI 10.1016/S0014-5793(97)00487-0, PII S0014579397004870
    • Ray, P., Ghosh, S. K., Zhang, D. H., Ray, A. (1997) Repression of interleukin-6 gene expression by 17 β-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-κ B by the estrogen receptor. FEBS Lett. 409, 79-85. (Pubitemid 27248571)
    • (1997) FEBS Letters , vol.409 , Issue.1 , pp. 79-85
    • Ray, P.1    Ghosh, S.K.2    Zhang, D.-H.3    Ray, A.4
  • 6
    • 0032452622 scopus 로고    scopus 로고
    • Testosterone: The crucial hormone responsible for depressing myocardial function in males after trauma-hemorrhage
    • DOI 10.1097/00000658-199806000-00002
    • Remmers, D. E., Cioffi, W. G., Bland, K. I., Wang, P., Angele, M. K., Chaudry, I. H. (1998) Testosterone: the crucial hormone responsible for depressing myocardial function in males after trauma-hemorrhage. Ann. Surg. 227, 790-799. (Pubitemid 29119526)
    • (1998) Annals of Surgery , vol.227 , Issue.6 , pp. 790-799
    • Remmers, D.E.1    Cioffi, W.G.2    Bland, K.I.3    Wang, P.4    Angele, M.K.5    Chaudry, I.H.6
  • 7
    • 33646789505 scopus 로고    scopus 로고
    • Gender differences in acute response to trauma-hemorrhage
    • DOI 10.1097/01.shk.0000191341.31530.5e, PII 0002438220051200100017
    • Choudhry, M. A., Schwacha, M. G., Hubbard, W. J., Kerby, J. D., Rue, L. W., Bland, K. I., Chaudry, I. H. (2005) Gender differences in acute response to trauma-hemorrhage. Shock 24 (Suppl. 1), 101-106. (Pubitemid 43756027)
    • (2005) Shock , vol.24 , Issue.SUPPL. 1 , pp. 101-106
    • Choudhry, M.A.1    Schwacha, M.G.2    Hubbard, W.J.3    Kerby, J.D.4    Rue, L.W.5    Bland, K.I.6    Chaudry, I.H.7
  • 8
    • 0036636476 scopus 로고    scopus 로고
    • The effect of intestinal ischemia and reperfusion injury on ICAM-1 expression, endothelial barrier function, neutrophil tissue influx, and protease inhibitor levels in rats
    • Olanders, K., Sun, Z., Borjesson, A., Dib, M., Andersson, E., Lasson, A., Ohlsson, T., Andersson, R. (2002) The effect of intestinal ischemia and reperfusion injury on ICAM-1 expression, endothelial barrier function, neutrophil tissue influx, and protease inhibitor levels in rats. Shock 18, 86-92.
    • (2002) Shock , vol.18 , pp. 86-92
    • Olanders, K.1    Sun, Z.2    Borjesson, A.3    Dib, M.4    Andersson, E.5    Lasson, A.6    Ohlsson, T.7    Andersson, R.8
  • 9
    • 0036596647 scopus 로고    scopus 로고
    • Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells
    • Dayal, S. D., Hasko, G., Lu, Q., Xu, D. Z., Caruso, J. M., Sambol, J. T., Deitch, E. A. (2002) Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells. Shock 17, 491-495.
    • (2002) Shock , vol.17 , pp. 491-495
    • Dayal, S.D.1    Hasko, G.2    Lu, Q.3    Xu, D.Z.4    Caruso, J.M.5    Sambol, J.T.6    Deitch, E.A.7
  • 10
    • 0031445340 scopus 로고    scopus 로고
    • L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism
    • Meldrum, D. R., McIntyre, R. C., Sheridan, B. C., Cleveland Jr., J. C., Fullerton, D. A., Harken, A. H. (1997) L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism. J. Trauma 43, 888-893.
    • (1997) J. Trauma , vol.43 , pp. 888-893
    • Meldrum, D.R.1    McIntyre, R.C.2    Sheridan, B.C.3    Cleveland Jr., J.C.4    Fullerton, D.A.5    Harken, A.H.6
  • 13
    • 34848856657 scopus 로고    scopus 로고
    • Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation
    • Hsu, J. T., Kan, W. H., Hsieh, C. H., Choudhry, M. A., Schwacha, M. G., Bland, K. I., Chaudry, I. H. (2007) Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. J. Leukoc. Biol. 82, 1019-1026.
    • (2007) J. Leukoc. Biol. , vol.82 , pp. 1019-1026
    • Hsu, J.T.1    Kan, W.H.2    Hsieh, C.H.3    Choudhry, M.A.4    Schwacha, M.G.5    Bland, K.I.6    Chaudry, I.H.7
  • 16
    • 33846406911 scopus 로고    scopus 로고
    • Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway
    • DOI 10.1097/01.sla.0000232523.88621.17, PII 0000065820070200000020
    • Shimizu, T., Yu, H. P., Hsieh, Y. C., Choudhry, M. A., Suzuki, T., Bland, K. I., Chaudry, I. H. (2007) Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway. Ann. Surg. 245, 297-304. (Pubitemid 46148490)
    • (2007) Annals of Surgery , vol.245 , Issue.2 , pp. 297-304
    • Shimizu, T.1    Yu, H.-P.2    Hsieh, Y.-C.3    Choudhry, M.A.4    Suzuki, T.5    Bland, K.I.6    Chaudry, I.H.7
  • 17
    • 33847346917 scopus 로고    scopus 로고
    • Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage
    • DOI 10.1016/j.yjmcc.2006.12.004, PII S0022282806010741
    • Yang, S., Hu, S., Choudhry, M. A., Rue III, L. W., Bland, K. I., Chaudry, I. H. (2007) Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. J. Mol. Cell. Cardiol. 42, 620-630. (Pubitemid 46349125)
    • (2007) Journal of Molecular and Cellular Cardiology , vol.42 , Issue.3 , pp. 620-630
    • Yang, S.1    Hu, S.2    Choudhry, M.A.3    Rue III, L.W.4    Bland, K.I.5    Chaudry, I.H.6
  • 20
    • 28844432578 scopus 로고    scopus 로고
    • The heme oxygenase system: Update 2005
    • Maines, M. D. (2005) The heme oxygenase system: update 2005. Antioxid. Redox Signal. 7, 1761-1766.
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 1761-1766
    • Maines, M.D.1
  • 21
    • 33750838526 scopus 로고    scopus 로고
    • Heme oxygenase-1 as a potential therapeutic target for hepatoprotection
    • Farombi, E. O., Surh, Y. J. (2006) Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. J. Biochem. Mol. Biol. 39, 479-491. (Pubitemid 44714527)
    • (2006) Journal of Biochemistry and Molecular Biology , vol.39 , Issue.5 , pp. 479-491
    • Farombi, E.O.1    Surh, Y.-J.2
  • 22
    • 0037382135 scopus 로고    scopus 로고
    • Heme oxygenase-1: A cellular Hercules
    • Zuckerbraun, B. S., Billiar, T. R. (2003) Heme oxygenase-1: a cellular Hercules. Hepatology 37, 742-744.
    • (2003) Hepatology , vol.37 , pp. 742-744
    • Zuckerbraun, B.S.1    Billiar, T.R.2
  • 24
    • 0032531163 scopus 로고    scopus 로고
    • Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats
    • Pannen, B. H., Kohler, N., Hole, B., Bauer, M., Clemens, M. G., Geiger, K. K. (1998) Protective role of endogenous carbon monoxide in hepatic microcirculatory dysfunction after hemorrhagic shock in rats. J. Clin. Invest. 102, 1220-1228. (Pubitemid 28436282)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.6 , pp. 1220-1228
    • Pannen, B.H.J.1    Kohler, N.2    Hole, B.3    Bauer, M.4    Clemens, M.G.5    Geiger, K.K.6
  • 25
    • 0031915553 scopus 로고    scopus 로고
    • Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver
    • DOI 10.1002/hep.510270327
    • Bauer, I., Wanner, G. A., Rensing, H., Alte, C., Miescher, E. A., Wolf, B., Pannen, B. H., Clemens, M. G., Bauer, M. (1998) Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver. Hepatology 27, 829-838. (Pubitemid 28103562)
    • (1998) Hepatology , vol.27 , Issue.3 , pp. 829-838
    • Bauer, I.1
  • 29
    • 34250376502 scopus 로고    scopus 로고
    • CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice
    • DOI 10.1186/1476-9255-4-11
    • Monson, K. M., Dowlatshahi, S., Crockett, E. T. (2007) CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice. J. Inflamm. (Lond.) 4, 11. (Pubitemid 46917421)
    • (2007) Journal of Inflammation , vol.4 , pp. 11
    • Monson, K.M.1    Dowlatshahi, S.2    Crockett, E.T.3
  • 30
    • 33646240128 scopus 로고    scopus 로고
    • Neutrophil degranulation and the effects of phosphodiesterase inhibition
    • Deree, J., Lall, R., Melbostad, H., Grant, M., Hoyt, D. B., Coimbra, R. (2006) Neutrophil degranulation and the effects of phosphodiesterase inhibition. J. Surg. Res. 133, 22-28.
    • (2006) J. Surg. Res. , vol.133 , pp. 22-28
    • Deree, J.1    Lall, R.2    Melbostad, H.3    Grant, M.4    Hoyt, D.B.5    Coimbra, R.6
  • 31
    • 0036156865 scopus 로고    scopus 로고
    • Elevation of plasma peptidoglycan and peripheral blood neutrophil activation during hemorrhagic shock: Plasma peptidoglycan reflects bacterial translocation and may affect neutrophil activation
    • Shimizu, T., Tani, T., Endo, Y., Hanasawa, K., Tsuchiya, M., Kodama, M. (2002) Elevation of plasma peptidoglycan and peripheral blood neutrophil activation during hemorrhagic shock: plasma peptidoglycan reflects bacterial translocation and may affect neutrophil activation. Crit. Care Med. 30, 77-82. (Pubitemid 34112180)
    • (2002) Critical Care Medicine , vol.30 , Issue.1 , pp. 77-82
    • Shimizu, T.1    Tani, T.2    Endo, Y.3    Hanasawa, K.4    Tsuchiya, M.5    Kodama, M.6
  • 32
    • 0038452749 scopus 로고    scopus 로고
    • Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide
    • Lehnert, M., Arteel, G. E., Smutney, O. M., Conzelmann, L. O., Zhong, Z., Thurman, R. G., Lemasters, J. J. (2003) Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock 19, 345-351.
    • (2003) Shock , vol.19 , pp. 345-351
    • Lehnert, M.1    Arteel, G.E.2    Smutney, O.M.3    Conzelmann, L.O.4    Zhong, Z.5    Thurman, R.G.6    Lemasters, J.J.7
  • 33
    • 0037702112 scopus 로고    scopus 로고
    • Administration of progesterone after trauma and hemorrhagic shock prevents hepatocellular injury
    • DOI 10.1001/archsurg.138.7.727
    • Kuebler, J. F., Yokoyama, Y., Jarrar, D., Toth, B., Rue III, L. W., Bland, K. I., Wang, P., Chaudry, I. H. (2003) Administration of progesterone after trauma and hemorrhagic shock prevents hepatocellular injury. Arch. Surg. 138, 727-734. (Pubitemid 36858151)
    • (2003) Archives of Surgery , vol.138 , Issue.7 , pp. 727-734
    • Kuebler, J.F.1    Yokoyama, Y.2    Jarrar, D.3    Toth, B.4    Rue III, L.W.5    Bland, K.I.6    Wang, P.7    Chaudry, I.H.8
  • 34
    • 1542404993 scopus 로고    scopus 로고
    • Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation
    • DOI 10.1097/01.CCM.0000114815.88622.9D
    • Xu, D. Z., Lu, Q., Adams, C. A., Issekutz, A. C., Deitch, E. A. (2004) Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation. Crit. Care Med. 32, 760-765. (Pubitemid 38340074)
    • (2004) Critical Care Medicine , vol.32 , Issue.3 , pp. 760-765
    • Xu, D.-Z.1    Lu, Q.2    Adams, C.A.3    Issekutz, A.C.4    Deitch, E.A.5
  • 39
    • 0042309594 scopus 로고    scopus 로고
    • Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation
    • Gaddipati, J. P., Sundar, S. V., Calemine, J., Seth, P., Sidhu, G. S., Maheshwari, R. K. (2003) Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation. Shock 19, 150-156.
    • (2003) Shock , vol.19 , pp. 150-156
    • Gaddipati, J.P.1    Sundar, S.V.2    Calemine, J.3    Seth, P.4    Sidhu, G.S.5    Maheshwari, R.K.6
  • 41
    • 0033454739 scopus 로고    scopus 로고
    • Regulation of intercellular adhesion molecule-1 (CD54) gene expression
    • Roebuck, K. A., Finnegan, A. (1999) Regulation of intercellular adhesion molecule-1 (CD54) gene expression. J. Leukoc. Biol. 66, 876-888. (Pubitemid 30010511)
    • (1999) Journal of Leukocyte Biology , vol.66 , Issue.6 , pp. 876-888
    • Roebuck, K.A.1    Finnegan, A.2
  • 42
    • 0033862489 scopus 로고    scopus 로고
    • Alcoholic fatty liver differentially induces a neutrophil-chemokine and hepatic necrosis after ischemia-reperfusion in rat
    • Yamada, S., Iida, T., Tabata, T., Nomoto, M., Kishikawa, H., Kohno, K., Eto, S. (2000) Alcoholic fatty liver differentially induces a neutrophilchemokine and hepatic necrosis after ischemia-reperfusion in rat. Hepatology 32, 278-288. (Pubitemid 30614660)
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 278-288
    • Yamada, S.1    Iida, T.2    Tabata, T.3    Nomoto, M.4    Kishikawa, H.5    Kohno, K.6    Eto, S.7
  • 43
    • 0036841931 scopus 로고    scopus 로고
    • Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion
    • Kato, A., Gabay, C., Okaya, T., Lentsch, A. B. (2002) Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion. Am. J. Pathol. 161, 1797-1803. (Pubitemid 35265537)
    • (2002) American Journal of Pathology , vol.161 , Issue.5 , pp. 1797-1803
    • Kato, A.1    Gabay, C.2    Okaya, T.3    Lentsch, A.B.4
  • 44
    • 0032080004 scopus 로고    scopus 로고
    • Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver
    • Chandler, J. M., Cohen, G. M., MacFarlane, M. (1998) Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J. Biol. Chem. 273, 10815-10818.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10815-10818
    • Chandler, J.M.1    Cohen, G.M.2    MacFarlane, M.3
  • 45
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • DOI 10.1084/jem.185.8.1481
    • Leist, M., Single, B., Castoldi, A. F., Kuhnle, S., Nicotera, P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185, 1481-1486. (Pubitemid 27187604)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.8 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 47
    • 0032496143 scopus 로고    scopus 로고
    • Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
    • DOI 10.1074/jbc.273.19.11401
    • Cai, J., Jones, D. P. (1998) Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J. Biol. Chem. 273, 11401-11404. (Pubitemid 28272028)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.19 , pp. 11401-11404
    • Cai, J.1    Jones, D.P.2
  • 48
    • 0033208768 scopus 로고    scopus 로고
    • A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock
    • Mota-Filipe, H., McDonald, M. C., Cuzzocrea, S., Thiemermann, C. (1999) A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. Shock 12, 255-261.
    • (1999) Shock , vol.12 , pp. 255-261
    • Mota-Filipe, H.1    McDonald, M.C.2    Cuzzocrea, S.3    Thiemermann, C.4
  • 50
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • DOI 10.1016/0092-8674(93)90509-O
    • Oltvai, Z. N., Milliman, C. L., Korsmeyer, S. J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619. (Pubitemid 23259742)
    • (1993) Cell , vol.74 , Issue.4 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 52
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl- 2 regulation of apoptosis
    • DOI 10.1126/science.275.5303.1132
    • Kluck, R. M., Bossy-Wetzel, E., Green, D. R., Newmeyer, D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136. (Pubitemid 27097313)
    • (1997) Science , vol.275 , Issue.5303 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 53
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson, D. W. (2000) From bench to clinic with apoptosis-based therapeutic agents. Nature 407, 810-816.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 54
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 55
    • 0034060334 scopus 로고    scopus 로고
    • Apoptosis and liver disease
    • Rust, C., Gores, G. J. (2000) Apoptosis and liver disease. Am. J. Med. 108, 567-574.
    • (2000) Am. J. Med. , vol.108 , pp. 567-574
    • Rust, C.1    Gores, G.J.2
  • 56
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw, W. C., Martins, L. M., Kaufmann, S. H. (1999) Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 68, 383-424.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 57
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and α and β
    • DOI 10.1210/en.138.3.863
    • Kuiper, G. G., Carlsson, B., Grandien, K., Enmark, E., Haggblad, J., Nilsson, S., Gustafsson, J. A. (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138, 863-870. (Pubitemid 27089735)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 59
    • 34247555378 scopus 로고    scopus 로고
    • The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage
    • DOI 10.1016/j.jhep.2007.01.019, PII S0168827807000682
    • Shimizu, T., Yu, H. P., Suzuki, T., Szalay, L., Hsieh, Y. C., Choudhry, M. A., Bland, K. I., Chaudry, I. H. (2007) The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage. J. Hepatol. 46, 1047-1054. (Pubitemid 46669731)
    • (2007) Journal of Hepatology , vol.46 , Issue.6 , pp. 1047-1054
    • Shimizu, T.1    Yu, H.-P.2    Suzuki, T.3    Szalay, L.4    Hsieh, Y.-C.5    Choudhry, M.A.6    Bland, K.I.7    Chaudry, I.H.8


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