Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver

Hepatology

Volumn 27, Issue 3, 1998, Pages 829-838

  Bauer, Inge ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIVERDIN; COBALT CHLORIDE; GLUTATHIONE; HEAT SHOCK PROTEIN 70; HEME OXYGENASE; ISOENZYME; LIPOPOLYSACCHARIDE; PROTOPORPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME POLYMORPHISM; HEME SYNTHESIS; HYPOTENSION; ITO CELL; LIVER HEMORRHAGE; LIVER ISCHEMIA; LIVER PARENCHYMA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION;

ANIMALS; COBALT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE (DECYCLIZING); ISOENZYMES; LIPOPOLYSACCHARIDES; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0031915553     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510270327     Document Type: Article

References (21)

1. Maines MD. Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 1988;2:2557-2568.
2. Tenhunen R, Marver HS, Schmid R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci U S A 1968;61:748-755.
3. Verma A, Hirsch DJ, Glatt CE, Ronnett GV, Snyder SH. Carbon monoxide: a putative neuronal messenger. Science 1993;259:381-384.
4. Furchgott RF, Jothianandan D. Endothelium-dependent and independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels 1991;28:52-61.
5. Utz J, Ullrich V. Carbon monoxide relaxes ileal smooth muscle through activation of guanylate cyclase. Biochem Pharmacol 1991;41:1195-1201.
6. Cruse I, Maines MD. Evidence suggesting that the two forms of heme oxygenase are products of different genes. J Biol Chem 1988;263:3348-3353.
7. Shibahara S, Mueller RM, Taguchi H. Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 1987;262:12889-12892.
8. Ewing JF, Maines MD. Rapid induction of heme oxygenase-1 mRNA and protein by hyperthermia in rat brain: heme oxygenase-2 is not a heat shock protein. Proc Natl Acad Sci U S A 1991;88:5364-5368.
9. Applegate LA, Luscher P, Tyrrell RM. Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells. Cancer Res 1991;51:974-978.
10. Bauer M, Pannen BHJ, Bauer I, Herzog C, Wanner GA, Hanselmann R, Zhang JX, et al. Evidence for a functional link between stress response and vascular control in hepatic portal circulation. Am J Physiol (Gastrointest Liver Physiol) 1996;271:G929-935.
11. Bissell DM, Hammacker L, Schmid R. Hemoglobin and erythrocyte catabolism in rat liver: the separate roles of parenchymal and sinusoidal cells. Blood 1972;40:812-822.
12. Maines MD, Trakshel GM, Kutty RK. Characterization of two constitutive forms of rat liver microsomal heme oxygenase: only one molecular species of the enzyme is inducible. J Biol Chem 1986;261:411-419.
13. Pannen BHJ, Bauer M, Noeldge-Schomburg GFE, Zhang JX, Robotham JL, Clemens MG, Geiger KK. Regulation of hepatic blood flow during resuscitation from hemorrhagic shock: role of NO and endothelins. Am J Physiol (Haert Circ Physiol) 1997;272:H2736-H2745.
14. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-162.
15. Shibahara S, Mueller RM, Taguchi H, Yoshida T. Cloning and expression of cDNA for rat heme oxygenase. Proc Natl Acad Sci U S A 1985;82(suppl) 23:7865-7869.
16. Rotenberg MO, Maines MD. Isolation, characterization, and expression in Escherichia coli of a cDNA encoding rat heme oxygenase 2. J Biol Chem 1990;265:7501-7506.
17. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983;132:6-13.
18. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilyzing the principle of protein-dye binding. Anal Biochem 1976; 72:248-254.
19. Laemmli, UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 1970;227:680-685.
20. Evers P, Uylings HBM. Microwave-stimulated antigen retrieval is pH and temperature dependent. J Histochem Cytochem 1994;42:1555-1563.
21. Kawada N, Tran-Thi TA, Klein H, Decker K. The contractional hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin-1 and nitric oxide in the regulation of sinusoidal tonus. Eur J Biochem 1993;213:815-823.