-
1
-
-
13244296604
-
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
-
10.1038/nbt1044 15580262
-
Cabantous S Terwilliger TC Waldo GS Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein Nat Biotechnol 2005, 23:102-107. 10.1038/nbt1044 15580262
-
(2005)
Nat Biotechnol
, vol.23
, pp. 102-107
-
-
Cabantous, S.1
Terwilliger, T.C.2
Waldo, G.S.3
-
2
-
-
33750483267
-
An intramolecular folding sensor for imaging estrogen receptor-ligand interactions
-
1635097 17043219 10.1073/pnas.0607385103
-
Paulmurugan R Gambhir SS An intramolecular folding sensor for imaging estrogen receptor-ligand interactions Proc Natl Acad Sci USA 2006, 103:15883-15888. 1635097 17043219 10.1073/pnas.0607385103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15883-15888
-
-
Paulmurugan, R.1
Gambhir, S.S.2
-
3
-
-
23944444109
-
Engineering allosteric protein switches by domain insertion
-
10.1093/protein/gzi048 16043448
-
Ostermeier M Engineering allosteric protein switches by domain insertion Protein Eng Des Sel 2005, 18:359-364. 10.1093/protein/gzi048 16043448
-
(2005)
Protein Eng Des Sel
, vol.18
, pp. 359-364
-
-
Ostermeier, M.1
-
4
-
-
0141757323
-
Reprogramming control of an allosteric signaling switch through modular recombination
-
10.1126/science.1085945 14512628
-
Dueber JE Yeh BJ Chak K Lim WA Reprogramming control of an allosteric signaling switch through modular recombination Science 2003, 301:1904-1908. 10.1126/science.1085945 14512628
-
(2003)
Science
, vol.301
, pp. 1904-1908
-
-
Dueber, J.E.1
Yeh, B.J.2
Chak, K.3
Lim, W.A.4
-
5
-
-
23844465160
-
Directed evolution of protein switches and their application to the creation of ligand-binding proteins
-
1183557 16061816 10.1073/pnas.0502673102
-
Guntas G Mansell TJ Kim JR Ostermeier M Directed evolution of protein switches and their application to the creation of ligand-binding proteins Proc Natl Acad Sci USA 2005, 102:11224-11229. 1183557 16061816 10.1073/pnas.0502673102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11224-11229
-
-
Guntas, G.1
Mansell, T.J.2
Kim, J.R.3
Ostermeier, M.4
-
6
-
-
36949011636
-
The G protein-coupled receptor subset of the rat genome
-
2117022 17892602 10.1186/1471-2164-8-338
-
Gloriam DE Fredriksson R Schioth HB The G protein-coupled receptor subset of the rat genome BMC Genomics 2007, 8:338. 2117022 17892602 10.1186/1471-2164-8-338
-
(2007)
BMC Genomics
, vol.8
, pp. 338
-
-
Gloriam, D.E.1
Fredriksson, R.2
Schioth, H.B.3
-
7
-
-
61949087315
-
The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents
-
2651185 19146662 10.1186/1471-2164-10-24
-
Haitina T Fredriksson R Foord SM Schioth HB Gloriam DE The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents BMC Genomics 2009, 10:24. 2651185 19146662 10.1186/1471-2164-10-24
-
(2009)
BMC Genomics
, vol.10
, pp. 24
-
-
Haitina, T.1
Fredriksson, R.2
Foord, S.M.3
Schioth, H.B.4
Gloriam, D.E.5
-
8
-
-
34548086194
-
The dog and rat olfactory receptor repertoires
-
1257466 16207354 10.1186/gb-2005-6-10-r83
-
Quignon P Giraud M Rimbault M Lavigne P Tacher S Morin E Retout E Valin AS Lindblad-Toh K Nicolas J Galibert F The dog and rat olfactory receptor repertoires Genome Biol 2005, 6:R83. 1257466 16207354 10.1186/ gb-2005-6-10-r83
-
(2005)
Genome Biol
, vol.6
-
-
Quignon, P.1
Giraud, M.2
Rimbault, M.3
Lavigne, P.4
Tacher, S.5
Morin, E.6
Retout, E.7
Valin, A.S.8
Lindblad-Toh, K.9
Nicolas, J.10
Galibert, F.11
-
9
-
-
34447620659
-
Modulating G-protein-coupled receptors: From traditional pharmacology to allosterics
-
10.1016/j.tips.2007.06.012 17644194
-
Gilchrist A Modulating G-protein-coupled receptors: From traditional pharmacology to allosterics Trends Pharmacol Sci 2007, 28:431-437. 10.1016/j.tips.2007.06.012 17644194
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 431-437
-
-
Gilchrist, A.1
-
10
-
-
0034894495
-
Sex and sugar in yeast: Two distinct GPCR systems
-
1083946 11463740 10.1093/embo-reports/kve132
-
Versele M Lemaire K Thevelein JM Sex and sugar in yeast: Two distinct GPCR systems EMBO Rep 2001, 2:574-579. 1083946 11463740 10.1093/ embo-reports/kve132
-
(2001)
EMBO Rep
, vol.2
, pp. 574-579
-
-
Versele, M.1
Lemaire, K.2
Thevelein, J.M.3
-
11
-
-
0036366975
-
The structural basis of G-protein-coupled receptor function and dysfunction in human diseases
-
11987825
-
Schoneberg T Schulz A Gudermann T The structural basis of G-protein-coupled receptor function and dysfunction in human diseases Rev Physiol Biochem Pharmacol 2002, 144:143-227. 11987825
-
(2002)
Rev Physiol Biochem Pharmacol
, vol.144
, pp. 143-227
-
-
Schoneberg, T.1
Schulz, A.2
Gudermann, T.3
-
12
-
-
0029818551
-
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: A site-directed spin-labeling study
-
10.1021/bi960849l 8823182
-
Altenbach C Yang K Farrens DL Farahbakhsh ZT Khorana HG Hubbell WL Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: A site-directed spin-labeling study Biochemistry 1996, 35:12470-12478. 10.1021/bi960849l 8823182
-
(1996)
Biochemistry
, vol.35
, pp. 12470-12478
-
-
Altenbach, C.1
Yang, K.2
Farrens, D.L.3
Farahbakhsh, Z.T.4
Khorana, H.G.5
Hubbell, W.L.6
-
13
-
-
0035932989
-
Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor
-
33412 11353823 10.1073/pnas.101126198
-
Ghanouni P Steenhuis JJ Farrens DL Kobilka BK Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor Proc Natl Acad Sci USA 2001, 98:5997-6002. 33412 11353823 10.1073/pnas.101126198
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5997-6002
-
-
Ghanouni, P.1
Steenhuis, J.J.2
Farrens, D.L.3
Kobilka, B.K.4
-
14
-
-
0035937786
-
Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling
-
10.1074/jbc.M004871200 11118431
-
Jensen AD Guarnieri F Rasmussen SG Asmar F Ballesteros JA Gether U Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling J Biol Chem 2001, 276:9279-9290. 10.1074/jbc.M004871200 11118431
-
(2001)
J Biol Chem
, vol.276
, pp. 9279-9290
-
-
Jensen, A.D.1
Guarnieri, F.2
Rasmussen, S.G.3
Asmar, F.4
Ballesteros, J.A.5
Gether, U.6
-
15
-
-
0033061256
-
Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6
-
10385699
-
Rasmussen SG Jensen AD Liapakis G Ghanouni P Javitch JA Gether U Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: Constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6 Mol Pharmacol 1999, 56:175-184. 10385699
-
(1999)
Mol Pharmacol
, vol.56
, pp. 175-184
-
-
Rasmussen, S.G.1
Jensen, A.D.2
Liapakis, G.3
Ghanouni, P.4
Javitch, J.A.5
Gether, U.6
-
16
-
-
31044432667
-
Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor
-
10.1021/bi051503q 16411743
-
Ward SD Hamdan FF Bloodworth LM Siddiqui NA Li JH Wess J Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor Biochemistry 2006, 45:676-685. 10.1021/bi051503q 16411743
-
(2006)
Biochemistry
, vol.45
, pp. 676-685
-
-
Ward, S.D.1
Hamdan, F.F.2
Bloodworth, L.M.3
Siddiqui, N.A.4
Li, J.H.5
Wess, J.6
-
17
-
-
34250376066
-
Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: Insights from fluorescence resonance energy transfer studies
-
10.1074/jbc.M611904200 17347144
-
Granier S Kim S Shafer AM Ratnala VR Fung JJ Zare RN Kobilka B Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: Insights from fluorescence resonance energy transfer studies J Biol Chem 2007, 282:13895-13905. 10.1074/jbc.M611904200 17347144
-
(2007)
J Biol Chem
, vol.282
, pp. 13895-13905
-
-
Granier, S.1
Kim, S.2
Shafer, A.M.3
Ratnala, V.R.4
Fung, J.J.5
Zare, R.N.6
Kobilka, B.7
-
18
-
-
34548824332
-
Distinct Structural Changes in a G Protein-coupled Receptor Caused by Different Classes of Agonist Ligands
-
10.1074/jbc.M704875200 17623649
-
Li JH Han SJ Hamdan FF Kim SK Jacobson KA Bloodworth LM Zhang X Wess J Distinct Structural Changes in a G Protein-coupled Receptor Caused by Different Classes of Agonist Ligands J Biol Chem 2007, 282:26284-26293. 10.1074/jbc.M704875200 17623649
-
(2007)
J Biol Chem
, vol.282
, pp. 26284-26293
-
-
Li, J.H.1
Han, S.J.2
Hamdan, F.F.3
Kim, S.K.4
Jacobson, K.A.5
Bloodworth, L.M.6
Zhang, X.7
Wess, J.8
-
19
-
-
29444444012
-
Molecular basis of inverse agonism in a G protein-coupled receptor
-
10.1038/nchembio705 16407989
-
Vilardaga JP Steinmeyer R Harms GS Lohse MJ Molecular basis of inverse agonism in a G protein-coupled receptor Nat Chem Biol 2005, 1:25-28. 10.1038/nchembio705 16407989
-
(2005)
Nat Chem Biol
, vol.1
, pp. 25-28
-
-
Vilardaga, J.P.1
Steinmeyer, R.2
Harms, G.S.3
Lohse, M.J.4
-
20
-
-
34247640671
-
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
-
1829280 17360345 10.1073/pnas.0700293104
-
Armbruster BN Li X Pausch MH Herlitze S Roth BL Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand Proc Natl Acad Sci USA 2007, 104:5163-5168. 1829280 17360345 10.1073/pnas.0700293104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5163-5168
-
-
Armbruster, B.N.1
Li, X.2
Pausch, M.H.3
Herlitze, S.4
Roth, B.L.5
-
21
-
-
0031940393
-
Controlling signaling with a specifically designed Gi-coupled receptor
-
18222 9419379 10.1073/pnas.95.1.352
-
Coward P Wada HG Falk MS Chan SD Meng F Akil H Conklin BR Controlling signaling with a specifically designed Gi-coupled receptor Proc Natl Acad Sci USA 1998, 95:352-357. 18222 9419379 10.1073/pnas.95.1.352
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 352-357
-
-
Coward, P.1
Wada, H.G.2
Falk, M.S.3
Chan, S.D.4
Meng, F.5
Akil, H.6
Conklin, B.R.7
-
22
-
-
0029851127
-
Membrane targeting and determination of transmembrane topology of the human vasopressin V2 receptor
-
10.1074/jbc.271.46.28844 8910530
-
Schulein R Rutz C Rosenthal W Membrane targeting and determination of transmembrane topology of the human vasopressin V2 receptor J Biol Chem 1996, 271:28844-28852. 10.1074/jbc.271.46.28844 8910530
-
(1996)
J Biol Chem
, vol.271
, pp. 28844-28852
-
-
Schulein, R.1
Rutz, C.2
Rosenthal, W.3
-
23
-
-
1142289021
-
Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila
-
10.1016/j.mod.2004.04.015 15172682
-
Nakano Y Nystedt S Shivdasani AA Strutt H Thomas C Ingham PW Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila Mech Dev 2004, 121:507-518. 10.1016/ j.mod.2004.04.015 15172682
-
(2004)
Mech Dev
, vol.121
, pp. 507-518
-
-
Nakano, Y.1
Nystedt, S.2
Shivdasani, A.A.3
Strutt, H.4
Thomas, C.5
Ingham, P.W.6
-
24
-
-
0346996806
-
Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor
-
10.1124/mol.64.6.1474 14645678
-
Zeng FY McLean AJ Milligan G Lerner M Chalmers DT Behan DP Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor Mol Pharmacol 2003, 64:1474-1484. 10.1124/mol.64.6.1474 14645678
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1474-1484
-
-
Zeng, F.Y.1
McLean, A.J.2
Milligan, G.3
Lerner, M.4
Chalmers, D.T.5
Behan, D.P.6
-
25
-
-
18744376919
-
Real-time monitoring of receptor and G-protein interactions in living cells
-
10.1038/nmeth743 15782186
-
Gales C Rebois RV Hogue M Trieu P Breit A Hebert TE Bouvier M Real-time monitoring of receptor and G-protein interactions in living cells Nat Methods 2005, 2:177-184. 10.1038/nmeth743 15782186
-
(2005)
Nat Methods
, vol.2
, pp. 177-184
-
-
Gales, C.1
Rebois, R.V.2
Hogue, M.3
Trieu, P.4
Breit, A.5
Hebert, T.E.6
Bouvier, M.7
-
26
-
-
0038729670
-
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
-
10.1038/nbt838 12808462
-
Vilardaga JP Bunemann M Krasel C Castro M Lohse MJ Measurement of the millisecond activation switch of G protein-coupled receptors in living cells Nat Biotechnol 2003, 21:807-812. 10.1038/nbt838 12808462
-
(2003)
Nat Biotechnol
, vol.21
, pp. 807-812
-
-
Vilardaga, J.P.1
Bunemann, M.2
Krasel, C.3
Castro, M.4
Lohse, M.J.5
-
27
-
-
0034724192
-
Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
-
16300 10725388 10.1073/pnas.060590697
-
Angers S Salahpour A Joly E Hilairet S Chelsky D Dennis M Bouvier M Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET) Proc Natl Acad Sci USA 2000, 97:3684-3689. 16300 10725388 10.1073/pnas.060590697
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3684-3689
-
-
Angers, S.1
Salahpour, A.2
Joly, E.3
Hilairet, S.4
Chelsky, D.5
Dennis, M.6
Bouvier, M.7
-
29
-
-
0029955946
-
Functional role of the third cytoplasmic loop in muscarinic receptor dimerization
-
10.1074/jbc.271.49.31055 8940100
-
Maggio R Barbier P Fornai F Corsini GU Functional role of the third cytoplasmic loop in muscarinic receptor dimerization J Biol Chem 1996, 271:31055-31060. 10.1074/jbc.271.49.31055 8940100
-
(1996)
J Biol Chem
, vol.271
, pp. 31055-31060
-
-
Maggio, R.1
Barbier, P.2
Fornai, F.3
Corsini, G.U.4
-
30
-
-
0029077235
-
Plasma membrane localization and functional rescue of truncated forms of a G protein-coupled receptor
-
10.1074/jbc.270.30.18000 7629108
-
Schoneberg T Liu J Wess J Plasma membrane localization and functional rescue of truncated forms of a G protein-coupled receptor J Biol Chem 1995, 270:18000-18006. 10.1074/jbc.270.30.18000 7629108
-
(1995)
J Biol Chem
, vol.270
, pp. 18000-18006
-
-
Schoneberg, T.1
Liu, J.2
Wess, J.3
-
31
-
-
0033516576
-
Identification and molecular characterization of m3 muscarinic receptor dimers
-
10.1074/jbc.274.27.19487 10383466
-
Zeng FY Wess J Identification and molecular characterization of m3 muscarinic receptor dimers J Biol Chem 1999, 274:19487-19497. 10.1074/ jbc.274.27.19487 10383466
-
(1999)
J Biol Chem
, vol.274
, pp. 19487-19497
-
-
Zeng, F.Y.1
Wess, J.2
-
32
-
-
66749146127
-
G protein-coupled receptors: Structural basis of receptor assemply and G protein recognition
-
Copenhagen: Blackwell Munksgaard Schwartz TW, Hjorth SA, Sandholm Kastrup J
-
Wess J Blin N Yun J Schoneberg T Liu J G protein-coupled receptors: structural basis of receptor assemply and G protein recognition Alfred Benzon Symposium 39: Structure and Function of 7TM Receptors Copenhagen: Blackwell Munksgaard Schwartz TW, Hjorth SA, Sandholm Kastrup J 1996, 43-56.
-
(1996)
Alfred Benzon Symposium 39: Structure and Function of 7TM Receptors
, pp. 43-56
-
-
Wess, J.1
Blin, N.2
Yun, J.3
Schoneberg, T.4
Liu, J.5
-
33
-
-
0036247440
-
Effects of removal of the N-terminal amino acid residues on the activity and conformation of firefly luciferase
-
10.1016/S1357-2725(02)00019-5 12007636
-
Wang XC Yang J Huang W He L Yu JT Lin QS Li W Zhou HM Effects of removal of the N-terminal amino acid residues on the activity and conformation of firefly luciferase Int J Biochem Cell Biol 2002, 34:983-991. 10.1016/ S1357-2725(02)00019-5 12007636
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 983-991
-
-
Wang, X.C.1
Yang, J.2
Huang, W.3
He, L.4
Yu, J.T.5
Lin, Q.S.6
Li, W.7
Zhou, H.M.8
-
34
-
-
0030584662
-
Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes
-
10.1016/S0969-2126(96)00033-0 8805533
-
Conti E Franks NP Brick P Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes Structure 1996, 4:287-298. 10.1016/S0969-2126(96)00033-0 8805533
-
(1996)
Structure
, vol.4
, pp. 287-298
-
-
Conti, E.1
Franks, N.P.2
Brick, P.3
-
35
-
-
0034928754
-
Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: Potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists
-
10.1023/A:1010951131496 11495349
-
Lysikova M Havlas Z Tucek S Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: Potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists Neurochem Res 2001, 26:383-394. 10.1023/ A:1010951131496 11495349
-
(2001)
Neurochem Res
, vol.26
, pp. 383-394
-
-
Lysikova, M.1
Havlas, Z.2
Tucek, S.3
-
36
-
-
33645775548
-
Constitutive activity of muscarinic acetylcholine receptors
-
10.1080/10799890600567349 16595339
-
Spalding TA Burstein ES Constitutive activity of muscarinic acetylcholine receptors J Recept Signal Transduct Res 2006, 26:61-85. 10.1080/10799890600567349 16595339
-
(2006)
J Recept Signal Transduct Res
, vol.26
, pp. 61-85
-
-
Spalding, T.A.1
Burstein, E.S.2
-
37
-
-
0020636518
-
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol
-
1153163 6309155
-
Berridge MJ Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol Biochem J 1983, 212:849-858. 1153163 6309155
-
(1983)
Biochem J
, vol.212
, pp. 849-858
-
-
Berridge, M.J.1
-
39
-
-
0041138283
-
Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication
-
508336 9294123 10.1172/JCI119678
-
Schoneberg T Sandig V Wess J Gudermann T Schultz G Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication J Clin Invest 1997, 100:1547-1556. 508336 9294123 10.1172/JCI119678
-
(1997)
J Clin Invest
, vol.100
, pp. 1547-1556
-
-
Schoneberg, T.1
Sandig, V.2
Wess, J.3
Gudermann, T.4
Schultz, G.5
|