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Volumn 18, Issue 112, 2009, Pages 113-124

Metabolic aspects of obstructive sleep apnoea syndrome

Author keywords

Adipokines; Adipose tissue; Hypoxia; Inflammation; Insulin resistance; Treatment

Indexed keywords

ADIPOCYTOKINE; ENDOCANNABINOID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; RIMONABANT;

EID: 66549104099     PISSN: 09059180     EISSN: None     Source Type: Journal    
DOI: 10.1183/09059180.00000109     Document Type: Conference Paper
Times cited : (30)

References (134)
  • 1
    • 66549108821 scopus 로고    scopus 로고
    • European Cooperation in Science and Technology
    • COST. European Cooperation in Science and Technology www.cost.esf.org
  • 2
    • 29544434090 scopus 로고    scopus 로고
    • Excess weight and sleep-disordered breathing
    • DOI 10.1152/japplphysiol.00587.2005
    • Young T, Peppard PE, Taheri S. Excess weight and sleep-disordered breathing. J Appl Physiol 2005; 99: 1592-1599. (Pubitemid 43014371)
    • (2005) Journal of Applied Physiology , vol.99 , Issue.4 , pp. 1592-1599
    • Young, T.1    Peppard, P.E.2    Taheri, S.3
  • 3
    • 0034569866 scopus 로고    scopus 로고
    • Obesity: Preventing and managing the global epidemic. Report of a WHO Consultation
    • World Health Organization. Geneva, World Health Organization
    • World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation. WHO Technical Report Series 894. Geneva, World Health Organization, 2000.
    • (2000) WHO Technical Report Series 894
  • 4
    • 12744268382 scopus 로고    scopus 로고
    • Childhood obesity, inflammation, and apnea. What is the future for our children?
    • Kelly A, Marcus CL. Childhood obesity, inflammation, and apnea. What is the future for our children? Am J Respir Crit Care Med 2005; 171: 202-203.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 202-203
    • Kelly, A.1    Marcus, C.L.2
  • 5
    • 15244344823 scopus 로고    scopus 로고
    • Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study
    • DOI 10.1016/S0140-6736(05)71141-7
    • Marin JM, Carrizo SJ, Vicente E, et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005; 365: 1046-1053. (Pubitemid 40386782)
    • (2005) Lancet , vol.365 , Issue.9464 , pp. 1046-1053
    • Marin, J.M.1    Carrizo, S.J.2    Vicente, E.3    Agusti, A.G.N.4
  • 6
    • 37149009516 scopus 로고    scopus 로고
    • Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk
    • DOI 10.1164/rccm.200611-1588OC
    • Buchner NJ, Sanner BM, Borgel J, et al. Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk. Am J Respir Crit Care Med 2007; 176: 1274-1280. (Pubitemid 350256482)
    • (2007) American Journal of Respiratory and Critical Care Medicine , vol.176 , Issue.12 , pp. 1274-1280
    • Buchner, N.J.1    Sanner, B.M.2    Borgel, J.3    Rump, L.C.4
  • 8
    • 33751289355 scopus 로고    scopus 로고
    • Increased incidence of coronary artery disease in sleep apnoea: A long-term follow-up
    • DOI 10.1183/09031936.06.00107805
    • Peker Y, Carlson J, Hedner J. Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up. Eur Respir J 2006; 28: 596-602. (Pubitemid 44794676)
    • (2006) European Respiratory Journal , vol.28 , Issue.3 , pp. 596-602
    • Peker, Y.1    Carlson, J.2    Hedner, J.3
  • 9
    • 33846188093 scopus 로고    scopus 로고
    • Sleep apnoea as an independent risk factor for cardiovascular disease: Current evidence, basic mechanisms and research priorities
    • Management Committee of the EU COST ACTION B26
    • McNicholas WT, Bonsignore MR, Management Committee of the EU COST ACTION B26. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 2007; 29: 156-178.
    • (2007) Eur Respir J , vol.29 , pp. 156-178
    • McNicholas, W.T.1    Bonsignore, M.R.2
  • 10
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • DOI 10.1038/nature05483, PII NATURE05483
    • Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006; 444: 847-853. (Pubitemid 46024991)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 12
    • 21544462572 scopus 로고    scopus 로고
    • Risk for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome
    • Ford ES. Risk for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome. Diab Care 2005; 28: 1769-1778.
    • (2005) Diab Care , vol.28 , pp. 1769-1778
    • Ford, E.S.1
  • 13
    • 34247193564 scopus 로고    scopus 로고
    • Metabolic syndrome: Is it a syndrome? Does it matter?
    • Kahn R. Metabolic syndrome: is it a syndrome? Does it matter? Circulation 2007; 115: 1806-1811.
    • (2007) Circulation , vol.115 , pp. 1806-1811
    • Kahn, R.1
  • 14
    • 34247255415 scopus 로고    scopus 로고
    • A work in progress, but a useful construct
    • Beaser RS, Levy P. A work in progress, but a useful construct. Circulation 2007; 115: 1812-1818.
    • (2007) Circulation , vol.115 , pp. 1812-1818
    • Beaser, R.S.1    Levy, P.2
  • 15
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • DOI 10.1038/nature05488, PII NATURE05488
    • Despréemieux I. Abdominal obesity and metabolic syndrome. Nature 2006; 444: 881-887. (Pubitemid 46024995)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 881-887
    • Despres, J.-P.1    Lemieux, I.2
  • 17
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 18
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome - A new worldwide definition
    • DOI 10.1016/S0140-6736(05)67402-8, PII S0140673605674028
    • Alberti KG, Zimmer P, Shaw J, et al. The metabolic syndrome: a new worldwide definition. Lancet 2005; 366: 1059-1062. (Pubitemid 41338752)
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1059-1062
    • Alberti, K.G.M.M.1    Zimmet, P.2    Shaw, J.3
  • 20
    • 33646037012 scopus 로고    scopus 로고
    • Obstructive sleep apnea and the metabolic syndrome in community-based Chinese adults in Hong Kong
    • Lam JCM, Lam B, Lam C-L, et al. Obstructive sleep apnea and the metabolic syndrome in community-based Chinese adults in Hong Kong. Respir Med 2006; 100: 980-987.
    • (2006) Respir Med , vol.100 , pp. 980-987
    • Lam, J.C.M.1    Lam, B.2    Lam, C.-L.3
  • 22
    • 34248569432 scopus 로고    scopus 로고
    • Obstructive sleep apnea syndrome is associated with some components of metabolic syndrome
    • DOI 10.1378/chest.06-1807
    • Kono M, Tatsumi K, Saibara T, et al. Obstructive sleep apnea syndrome is associated with some component of metabolic syndrome. Chest 2007; 131: 1387-1392. (Pubitemid 46762343)
    • (2007) Chest , vol.131 , Issue.5 , pp. 1387-1392
    • Kono, M.1    Tatsumi, K.2    Saibara, T.3    Nakamura, A.4    Tanabe, N.5    Takiguchi, Y.6    Kuriyama, T.7
  • 25
    • 0027937669 scopus 로고
    • Plasma insulin and lipid levels in untreated obstructive sleep apnoea and snoring; their comparison with matched controls and response to treatment
    • Davies RJ, Turner R, Crosby J, et al. Plasma insulin and lipid levels in untreated obstructive sleep apnea and snoring; their comparison with matched controls and response to treatment. J Sleep Res 1994; 3: 180-185. (Pubitemid 24311373)
    • (1994) Journal of Sleep Research , vol.3 , Issue.3 , pp. 180-185
    • Davies, R.J.O.1    Turner, R.2    Crosby, J.3    Stradling, J.R.4
  • 26
    • 3242667810 scopus 로고    scopus 로고
    • Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea
    • Barcelò A, Barbè F, Llompart E, et al. Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea. Am J Med 2004; 15: 118-121.
    • (2004) Am J Med , vol.15 , pp. 118-121
    • Barcelò, A.1    Barbè, F.2    Llompart, E.3
  • 27
    • 33751253095 scopus 로고    scopus 로고
    • Obstructive sleep apnoea is independently associated with the metabolic syndrome but not insulin resistance state
    • DOI 10.1186/1475-2840-5-22
    • Gruber A, Horwood F, Sithole J, et al. Obstructive sleep apnea is independently associated with the metabolic syndrome but not insulin resistance state. Cardiovasc Diabetol 2006; 5: 22-29. (Pubitemid 44781864)
    • (2006) Cardiovascular Diabetology , vol.5 , pp. 22
    • Gruber, A.1    Horwood, F.2    Sithole, J.3    Ali, N.J.4    Idris, I.5
  • 29
    • 34548150368 scopus 로고    scopus 로고
    • Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetes
    • DOI 10.1136/thx.2006.074351
    • West SD, Nicoll DJ, Wallace TM, et al. Effect of CPAP on insulin resistance andHbA1c inmenwith obstructive sleep apnoea and type 2 diabetes. Thorax 2007; 62: 969-974. (Pubitemid 350084496)
    • (2007) Thorax , vol.62 , Issue.11 , pp. 969-974
    • West, S.D.1    Nicoll, D.J.2    Wallace, T.M.3    Matthews, D.R.4    Stradling, J.R.5
  • 33
    • 35148854599 scopus 로고    scopus 로고
    • Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
    • DOI 10.1152/ajpendo.00435.2007
    • Ye J, Gao Z, Yin J, et al. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab 2007; 293: E1118-E1128. (Pubitemid 47535846)
    • (2007) American Journal of Physiology - Endocrinology and Metabolism , vol.293 , Issue.4
    • Ye, J.1    Gao, Z.2    Yin, J.3    He, Q.4
  • 36
    • 2442580978 scopus 로고    scopus 로고
    • Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome
    • DOI 10.1016/j.ehj.2004.02.021
    • Coughlin SR, Mawdsley L, Mugarza JA, et al. Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 2004; 25: 735-741. (Pubitemid 38647933)
    • (2004) European Heart Journal , vol.25 , Issue.9 , pp. 735-741
    • Coughlin, S.R.1    Mawdsley, L.2    Mugarza, J.A.3    Calverley, P.M.A.4    Wilding, J.P.H.5
  • 37
    • 0038009871 scopus 로고    scopus 로고
    • Metabolic disturbances in obesity versus sleep apnoea: The importance of visceral obesity and insulin resistance
    • DOI 10.1046/j.1365-2796.2003.01177.x
    • Vgontzas AN, Bixler EO, Chrousos GP. Metabolic disturbances in obesity versus sleep apnoea: the importance of visceral obesity and insulin resistance. J Intern Med 2003; 254: 32-44. (Pubitemid 36819129)
    • (2003) Journal of Internal Medicine , vol.254 , Issue.1 , pp. 32-44
    • Vgontzas, A.N.1    Bixler, E.O.2    Chrousos, G.P.3
  • 38
    • 0033578481 scopus 로고    scopus 로고
    • Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapy
    • Chin K, Shimizu K, Nakamura T, et al. Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapy. Circulation 1999; 100: 706-712. (Pubitemid 29383639)
    • (1999) Circulation , vol.100 , Issue.7 , pp. 706-712
    • Chin, K.1    Shimizu, K.2    Nakamura, T.3    Narai, N.4    Masuzaki, H.5    Ogawa, Y.6    Mishima, M.7    Nakamura, T.8    Nakao, K.9    Ohi, M.10
  • 39
    • 34248645632 scopus 로고    scopus 로고
    • The metabolic consequences of sleep deprivation
    • DOI 10.1016/j.smrv.2007.01.002, PII S1087079207000202
    • Knutson KL, Spiegel K, Penev P, et al. The metabolic consequences of sleep deprivation. Sleep Med Rev 2007; 11: 163-178. (Pubitemid 46778995)
    • (2007) Sleep Medicine Reviews , vol.11 , Issue.3 , pp. 163-178
    • Knutson, K.L.1    Spiegel, K.2    Penev, P.3    Van Cauter, E.4
  • 40
    • 10044287245 scopus 로고    scopus 로고
    • Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite
    • Spiegel K, Leproult R, L'Hermite-Balériaux M, et al. Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 2004; 141: 846-850. (Pubitemid 39601178)
    • (2004) Annals of Internal Medicine , vol.141 , Issue.11 , pp. 846-850
    • Spiegel, K.1    Tasali, E.2    Penev, P.3    Van Cauter, E.4
  • 41
    • 15744378271 scopus 로고    scopus 로고
    • Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index
    • DOI 10.1371/journal.pmed.0010062, e62
    • Taheri S, Lin L, Austin D, et al. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 2004; e62. (Pubitemid 40418884)
    • (2004) PLoS Medicine , vol.1 , Issue.3 , pp. 210-217
    • Taheri, S.1    Lin, L.2    Austin, D.3    Young, T.4    Mignot, E.5
  • 42
    • 3042538917 scopus 로고    scopus 로고
    • The association between short sleep duration and obesity in young adults: A 13-year prospective study
    • Hasler G, Buysse DJ, Klaghofer R, et al. The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep 2004; 27: 661-666. (Pubitemid 38823362)
    • (2004) Sleep , vol.27 , Issue.4 , pp. 661-666
    • Hasler, G.1    Buysse, D.J.2    Klaghofer, R.3    Gamma, A.4    Ajdacic, V.5    Eich, D.6    Rossler, W.7    Angst, J.8
  • 43
    • 38949137860 scopus 로고    scopus 로고
    • Slow-wave sleep and the risk of type 2 diabetes in humans
    • Tasali E, Leproult R, Ehrmann DA, et al. Slow-wave sleep and the risk of type 2 diabetes in humans. Proc Natl Acad Sci USA 2008; 105: 1044-1049.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1044-1049
    • Tasali, E.1    Leproult, R.2    Ehrmann, D.A.3
  • 45
    • 34548514172 scopus 로고    scopus 로고
    • Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers
    • Haack M, Sanchez E, Mullington JM. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 2007; 30: 1145-1152. (Pubitemid 47378957)
    • (2007) Sleep , vol.30 , Issue.9 , pp. 1145-1152
    • Haack, M.1    Sanchez, E.2    Mullington, J.M.3
  • 46
    • 33748796064 scopus 로고    scopus 로고
    • Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation
    • DOI 10.1001/archinte.166.16.1756
    • Irwin MR, Wang M, Campomayor CO, et al. Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. Arch Intern Med 2006; 166: 1756-1762. (Pubitemid 44414465)
    • (2006) Archives of Internal Medicine , vol.166 , Issue.16 , pp. 1756-1762
    • Irwin, M.R.1    Wang, M.2    Campomayor, C.O.3    Collado-Hidalgo, A.4    Cole, S.5
  • 48
    • 26244440570 scopus 로고    scopus 로고
    • Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines
    • DOI 10.1016/j.neuroscience.2005.06.090, PII S0306452205007529
    • Johnson JD, Campisi J, Sharkey CM, et al. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience 2005; 135: 1295-1307. (Pubitemid 41416690)
    • (2005) Neuroscience , vol.135 , Issue.4 , pp. 1295-1307
    • Johnson, J.D.1    Campisi, J.2    Sharkey, C.M.3    Kennedy, S.L.4    Nickerson, M.5    Greenwood, B.N.6    Fleshner, M.7
  • 49
    • 0037126526 scopus 로고    scopus 로고
    • Third Report on the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report on the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-3221.
    • (2002) Circulation , vol.106 , pp. 3143-3221
  • 50
    • 0031720540 scopus 로고    scopus 로고
    • "Syndrome Z": The interaction of sleep apnoea, vascular risk factors and heart disease
    • Wilcox I, McNamara SG, Collins FL, et al. "Syndrome Z": the interaction of sleep apnoea, vascular risk factors and heart disease. Thorax 1998; 53: Suppl. 3, S25-S28.
    • (1998) Thorax , vol.53 , Issue.SUPPL. 3
    • Wilcox, I.1    McNamara, S.G.2    Collins, F.L.3
  • 56
    • 33846855124 scopus 로고    scopus 로고
    • Increasing trends in waist circumference and abdominal obesity among U.S. adults
    • Li C, Ford ES, McGuire LC, et al. Increasing trends in waist circumference and abdominal obesity among US adults. Obesity 2007; 15: 216-224. (Pubitemid 46219802)
    • (2007) Obesity , vol.15 , Issue.1 , pp. 216-224
    • Chaoyang, L.1    Ford, E.S.2    McGuire, L.C.3    Mokdad, A.H.4
  • 57
    • 33847022752 scopus 로고    scopus 로고
    • Estimated burden of paediatric obesity and co-morbidities in Europe. Part 2. Numbers of children with indicators of obesity-related disease
    • Lobstein T, Jackson-Leach R. Estimated burden of paediatric obesity and co-morbidities in Europe. Part 2. Numbers of children with indicators of obesity-related disease. Int J Pediatr Obes 2006; 1: 33-41.
    • (2006) Int J Pediatr Obes , vol.1 , pp. 33-41
    • Lobstein, T.1    Jackson-Leach, R.2
  • 58
    • 33646567446 scopus 로고    scopus 로고
    • Obesity in childhood and adolescence: A review in the interface between adipocyte physiology and clinical challenges
    • Körner A, Blüher S, Kapellen T, et al. Obesity in childhood and adolescence: a review in the interface between adipocyte physiology and clinical challenges. Hormones (Athens) 2005; 4: 189-199.
    • (2005) Hormones (Athens) , vol.4 , pp. 189-199
    • Körner, A.1    Blüher, S.2    Kapellen, T.3
  • 59
    • 0036830614 scopus 로고    scopus 로고
    • Is obesity associated with poor sleep quality in adolescents?
    • Gupta NK, Mueller WH, Chan W, et al. Is obesity associated with poor sleep quality in adolescents? Am J Hum Biol 2002; 14: 762-768.
    • (2002) Am J Hum Biol , vol.14 , pp. 762-768
    • Gupta, N.K.1    Mueller, W.H.2    Chan, W.3
  • 61
    • 0036264480 scopus 로고    scopus 로고
    • Reduced risk for overweight and obesity in 5- And 6-y-old children by duration of sleep - a cross-sectional study
    • DOI 10.1038/sj.ijo.0801980
    • Von Kries R, Toschke AM, Wurmser H, et al. Reduced risk for overweight and obesity in 5- and 6-y-old children by duration of sleep-a cross-sectional study. Int J Obes Relat Metab Disord 2002; 26: 710-716. (Pubitemid 34499292)
    • (2002) International Journal of Obesity , vol.26 , Issue.5 , pp. 710-716
    • Von Kries, R.1    Toschke, A.M.2    Wurmser, H.3    Sauerwald, T.4    Koletzko, B.5
  • 65
    • 38349073396 scopus 로고    scopus 로고
    • Elevated serum aminotransferase levels in children at risk for obstructive sleep apnea
    • Kheirandish-Gozal L, Capdevila OS, Kheirandish E, et al. Elevated serum aminotransferase levels in children at risk for obstructive sleep apnea. Chest 2008; 133: 92-99.
    • (2008) Chest , vol.133 , pp. 92-99
    • Kheirandish-Gozal, L.1    Capdevila, O.S.2    Kheirandish, E.3
  • 67
    • 34248377344 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 and its role in insulin resistance
    • DOI 10.1097/MOL.0b013e3281338546, PII 0004143320070600000006
    • Sell H, Eckel J. Monocyte chemotactic protein-1 and its role in insulin resistance. Curr Opin Lipidol 2007; 18: 258-262. (Pubitemid 46743048)
    • (2007) Current Opinion in Lipidology , vol.18 , Issue.3 , pp. 258-262
    • Sell, H.1    Eckel, J.2
  • 68
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity?
    • Trayhurn P, Wang B, Wood S. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 2008; 100: 227-235.
    • (2008) Br J Nutr , vol.100 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, S.3
  • 69
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • DOI 10.1038/372425a0
    • Zhang Y, Proenca P, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432. (Pubitemid 24365442)
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 70
    • 0034890103 scopus 로고    scopus 로고
    • Physiological role of adipose tissue: White adipose tissue as an endocrine and secretory organ
    • Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 2001; 60: 329-339. (Pubitemid 32772448)
    • (2001) Proceedings of the Nutrition Society , vol.60 , Issue.3 , pp. 329-339
    • Trayhurn, P.1    Beattie, J.H.2
  • 72
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • DOI 10.1079/BJN20041213
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92: 347-355. (Pubitemid 40277057)
    • (2004) British Journal of Nutrition , vol.92 , Issue.3 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 73
    • 34547153223 scopus 로고    scopus 로고
    • Gene regulation under low oxygen: Holding your breath for transcription
    • DOI 10.1016/j.tibs.2007.06.005, PII S096800040700148X
    • Rocha S. Gene regulation under low oxygen: holding your breath for transcription. Trends Biochem Sci 2007; 32: 389-397. (Pubitemid 47126857)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.8 , pp. 389-397
    • Rocha, S.1
  • 75
    • 0036327970 scopus 로고    scopus 로고
    • Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes
    • Dietze D, Koenen M, Röhrig K, et al. Impairment of insulin signaling in human skeletal muscle cells by coculture with human adipocytes. Diabetes 2002; 51: 2369-2376. (Pubitemid 34827384)
    • (2002) Diabetes , vol.51 , Issue.8 , pp. 2369-2376
    • Dietze, D.1    Koenen, M.2    Rohrig, K.3    Horikoshi, H.4    Hanner, H.5    Eckel, J.6
  • 77
    • 0346880505 scopus 로고    scopus 로고
    • Inflammation and the IKK beta/IKB/NF-kB axis in obesity- and diet-induced insulin resistance
    • Shoelson SE, Lee J, Yuan M. Inflammation and the IKK beta/IKB/NF-kB axis in obesity- and diet-induced insulin resistance. Int J Obes Relat Metab Disord 2003; 27: Suppl. 3, S49-S52.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.SUPPL. 3
    • Shoelson, S.E.1    Lee, J.2    Yuan, M.3
  • 78
    • 34249946263 scopus 로고    scopus 로고
    • The endocannabinoid system: A new target for the regulation of energy balance and metabolism
    • DOI 10.1097/HPC.0b013e318057d4b4, PII 0013257720070600000002
    • Després JP. The endocannabinoid system: a new target for the regulation of energy balance and metabolism. Crit Pathw Cardiol 2007; 6: 46-50. (Pubitemid 46878231)
    • (2007) Critical Pathways in Cardiology , vol.6 , Issue.2 , pp. 46-50
    • Despres, J.-P.1
  • 79
    • 0025993870 scopus 로고
    • Circadian variation and cardiovascular disease
    • Muller JE, Tofler GH. Circadian variation and cardiovascular disease. N Engl J Med 1991; 325: 1038-1039.
    • (1991) N Engl J Med , vol.325 , pp. 1038-1039
    • Muller, J.E.1    Tofler, G.H.2
  • 81
    • 36348961277 scopus 로고    scopus 로고
    • Circadian clocks: Regulators of endocrine and metabolic rhythms
    • DOI 10.1677/JOE-07-0378
    • Hastings M, O'Neill JS, Maywood ES. Circadian clocks: regulators of endocrine and metabolic rhythms. J Endocrinol 2007; 195: 187-198. (Pubitemid 350143100)
    • (2007) Journal of Endocrinology , vol.195 , Issue.2 , pp. 187-198
    • Hastings, M.1    O'Neill, J.S.2    Maywood, E.S.3
  • 84
    • 33750440787 scopus 로고    scopus 로고
    • Peroxisome Proliferator-Activated Receptors at the Crossroads of Obesity, Diabetes, and Cardiovascular Disease
    • DOI 10.1016/j.jacc.2006.04.097, PII S0735109706018109
    • Gilde AJ, Fruchart J-C, Staels B. Peroxisome proliferated-activated receptors at the crossroads of obesity, diabetes and cardiovascular disease. J Am Coll Cardiol 2006; 48: A24-A32. (Pubitemid 44648644)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.9 SUPPL.
    • Gilde, A.J.1    Fruchart, J.-C.2    Staels, B.3
  • 85
    • 33847006604 scopus 로고    scopus 로고
    • Review: Peroxisome proliferator-activated receptor γ and adipose tissue - Understanding obesity-related changes in regulation of lipid and glucose metabolism
    • DOI 10.1210/jc.2006-1268
    • Sharma AM, Staels B. Peroxisome proliferator-activated receptor-c and adipose tissue. Understanding obesity-related changes in regulation of lipid and glucose metabolism. J Clin Endocrinol Metab 2007; 92: 386-395. (Pubitemid 46255265)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.2 , pp. 386-395
    • Sharma, A.M.1    Staels, B.2
  • 87
    • 2442711384 scopus 로고    scopus 로고
    • Peroxisome proliferated-activated receptors and atherogenesis. Regulators of gene expression in vascular cells
    • Marx N, Duez H, Fruchart J-C, et al. Peroxisome proliferated-activated receptors and atherogenesis. Regulators of gene expression in vascular cells. Circ Res 2004; 94: 1168-1178.
    • (2004) Circ Res , vol.94 , pp. 1168-1178
    • Marx, N.1    Duez, H.2    Fruchart, J.-C.3
  • 88
    • 34248664441 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage cholesterol trafficking by PPARα and LXR
    • DOI 10.1042/BST0341128
    • Chinetti G, Fruchart JC, Staels B. Transcriptional regulation of macrophage cholesterol trafficking by PPARa and LXR. Biochem Soc Trans 2006; 34: 1128-1131. (Pubitemid 46769003)
    • (2006) Biochemical Society Transactions , vol.34 , Issue.6 , pp. 1128-1131
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 89
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • DOI 10.1172/JCI29881
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007; 117: 175-184. (Pubitemid 46048464)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 91
    • 0033694955 scopus 로고    scopus 로고
    • The regulation of body fat distribution and the modulation of insulin action
    • Cases JA, Barzilai N. The regulation of body fat distribution and the modulation of insulin action. Int J Obes Relat Metab Disord 2000; 24: Suppl. 4, S63-S66.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.SUPPL. 4
    • Cases, J.A.1    Barzilai, N.2
  • 92
    • 13244279594 scopus 로고    scopus 로고
    • Regional differences of insulin action in adipose tissue: Insights from in vivo and in vitro studies
    • DOI 10.1111/j.1365-201X.2004.01385.x
    • Giorgino F, Laviola L, Eriksson JW. Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies. Acta Physiol Scand 2005; 183: 13-30. (Pubitemid 40188033)
    • (2005) Acta Physiologica Scandinavica , vol.183 , Issue.1 , pp. 13-30
    • Giorgino, F.1    Laviola, L.2    Eriksson, J.W.3
  • 93
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients - RIO-North America: A randomized controlled trial
    • DOI 10.1001/jama.295.7.761
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 2006; 295: 761-775. (Pubitemid 43244304)
    • (2006) Journal of the American Medical Association , vol.295 , Issue.7 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3    Devin, J.4    Rosenstock, J.5
  • 94
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-Year experience from the RIO-Europe study
    • DOI 10.1016/S0140-6736(05)66374-X
    • Van Gaal LF, Rissanen AM, Scheen AJ, et al. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005; 365: 1389-1397. (Pubitemid 40523733)
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 95
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • DOI 10.1056/NEJMoa044537
    • Després JP, Golay A, Sjö strömL, et al. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 2005; 353: 2121-2134. (Pubitemid 41653104)
    • (2005) New England Journal of Medicine , vol.353 , Issue.20 , pp. 2121-2134
    • Despres, J.-P.1    Golay, A.2    Sjostrom, L.3
  • 96
    • 33751001942 scopus 로고    scopus 로고
    • Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study
    • DOI 10.1016/S0140-6736(06)69571-8, PII S0140673606695718
    • Scheen AJ, Finer N, Hollander P, et al. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 2006; 368: 1660-1672. (Pubitemid 46048528)
    • (2006) Lancet , vol.368 , Issue.9548 , pp. 1660-1672
    • Scheen, A.J.1    Finer, N.2    Hollander, P.3    Jensen, M.D.4    Van Gaal, L.F.5
  • 97
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis and coronary artery disease. N Engl J Med 2005; 352: 1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 98
    • 33745004785 scopus 로고    scopus 로고
    • Biomarkers of cardiovascular disease: Molecular basis and practical considerations
    • DOI 10.1161/CIRCULATIONAHA.104.482570, PII 0000301720060516000014
    • Vasan RS. Biomarkers of cardiovascular disease: molecular basis and practical considerations. Circulation 2006; 113: 2335-2362. (Pubitemid 43947980)
    • (2006) Circulation , vol.113 , Issue.19 , pp. 2335-2362
    • Vasan, R.S.1
  • 100
    • 27444448072 scopus 로고    scopus 로고
    • Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
    • DOI 10.1161/CIRCULATIONAHA.105.556746
    • Ryan S, Taylor CT, McNicholas WT. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 2005; 112: 2660-2667. (Pubitemid 41532603)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2660-2667
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 101
  • 102
    • 0037418181 scopus 로고    scopus 로고
    • Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure
    • DOI 10.1161/01.CIR.0000052627.99976.18
    • Yokoe, T, Minoguchi K, Matsuo H, et al. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 2003; 107: 1129-1134. (Pubitemid 36297204)
    • (2003) Circulation , vol.107 , Issue.8 , pp. 1129-1134
    • Yokoe, T.1    Minoguchi, K.2    Matsuo, H.3    Oda, N.4    Minoguchi, H.5    Yoshino, G.6    Hirano, T.7    Adachi, M.8
  • 103
    • 34848840911 scopus 로고    scopus 로고
    • Effects of CPAP on early signs of atherosclerosis in obstructive sleep apnea
    • Drager LF, Bortolotto LA, Figueiredo AC, et al. Effects of CPAP on early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med 2007; 176: 706-712.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 706-712
    • Drager, L.F.1    Bortolotto, L.A.2    Figueiredo, A.C.3
  • 104
    • 33847267684 scopus 로고    scopus 로고
    • A critical role for p38 map kinase in NF-κB signaling during intermittent hypoxia/reoxygenation
    • DOI 10.1016/j.bbrc.2007.02.015, PII S0006291X07002860
    • Ryan SM, McNicholas WT, Taylor CT. A critical role for P38-MAP kinase in NFkB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 2007; 355: 728-733. (Pubitemid 46330212)
    • (2007) Biochemical and Biophysical Research Communications , vol.355 , Issue.3 , pp. 728-733
    • Ryan, S.1    McNicholas, W.T.2    Taylor, C.T.3
  • 105
    • 33645122617 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia activates nuclear factor-kB in cardiovascular tissues in vivo
    • Greenberg H, Ye X, Wilson D, et al. Chronic intermittent hypoxia activates nuclear factor-kB in cardiovascular tissues in vivo. Biochem Biophys Res Commun 2006; 343: 591-598.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 591-598
    • Greenberg, H.1    Ye, X.2    Wilson, D.3
  • 106
    • 33645114153 scopus 로고    scopus 로고
    • Activation of nuclear factor kB in obstructive sleep apnea: A pathway leading to systemic inflammation
    • DOI 10.1007/s11325-005-0046-6
    • Htoo AK, Greenberg H, Tongia S, et al. Activation of nuclear factor-kB in obstructive sleep apnea: a pathway leading to systemic inflammation. Sleep Breath 2006; 10: 43-50. (Pubitemid 44193436)
    • (2006) Sleep and Breathing , vol.10 , Issue.1 , pp. 43-50
    • Htoo, A.K.1    Greenberg, H.2    Tongia, S.3    Chen, G.4    Henderson, T.5    Wilson, D.6    Liu, S.F.7
  • 108
    • 0037490210 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and its biomedical relevance
    • DOI 10.1074/jbc.R200030200
    • Huang LE, Bunn HF. Hypoxia-inducible factor and its biomedical relevance. J Biol Chem 2003; 278: 19575-19578. (Pubitemid 36799137)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.22 , pp. 19575-19578
    • Huang, L.E.1    Bunn, H.F.2
  • 109
    • 34547883937 scopus 로고    scopus 로고
    • HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia
    • Semenza GL, PrabhakarNR. HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia. Antioxid Redox Signal 2007; 9: 1391-1396.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 1391-1396
    • Semenza, G.L.1    Prabhakar, N.R.2
  • 110
    • 33751329032 scopus 로고    scopus 로고
    • Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
    • DOI 10.1113/jphysiol.2006.114033
    • Peng YJ, Yuan G, Ramakrishnan D, et al. Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposedto intermittenthypoxia. JPhysiol 2006; 577: 705-716. (Pubitemid 44804021)
    • (2006) Journal of Physiology , vol.577 , Issue.2 , pp. 705-716
    • Peng, Y.-J.1    Yuan, G.2    Ramakrishnan, D.3    Sharma, S.D.4    Bosch-Marce, M.5    Kumar, G.K.6    Semenza, G.L.7    Prabhakar, N.R.8
  • 112
    • 34548514172 scopus 로고    scopus 로고
    • Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers
    • Haack M, Sanchez E, Mullington JM. Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep 2007; 30: 1145-1152. (Pubitemid 47378957)
    • (2007) Sleep , vol.30 , Issue.9 , pp. 1145-1152
    • Haack, M.1    Sanchez, E.2    Mullington, J.M.3
  • 114
    • 0036528981 scopus 로고    scopus 로고
    • Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients
    • Dyugovskaya L, Lavie P, Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 2002; 165: 934-939. (Pubitemid 34774660)
    • (2002) American Journal of Respiratory and Critical Care Medicine , vol.165 , Issue.7 , pp. 934-939
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 115
    • 0037316130 scopus 로고    scopus 로고
    • Obstructive sleep apnoea syndrome - An oxidative stress disorder
    • DOI 10.1053/smrv.2002.0261
    • Lavie L. Obstructive sleep apnoea syndrome - an oxidative stress disorder. Sleep Med Rev 2003; 7: 35-51. (Pubitemid 36188305)
    • (2003) Sleep Medicine Reviews , vol.7 , Issue.1 , pp. 35-51
    • Lavie, L.1
  • 118
    • 0042165846 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of blood cd T cells in sleep apnea
    • Dyugovskaya L, Lavie P, Lavie L. Phenotypic and functional characterization of blood cd T cells in sleep apnea. Am J Respir Crit Care Med 2003; 168: 242-249.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 242-249
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 123
    • 11844284749 scopus 로고    scopus 로고
    • Overweight and obese patients in a primary care population report less sleep than patients with a normal body mass index
    • DOI 10.1001/archinte.165.1.25
    • Vorona RD, Winn MP, Babineau TW, et al. Overweight and obese patients in a primary care population report less sleep than patients with a normal body mass index. Arch Intern Med 2005; 165: 25-30. (Pubitemid 40096078)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.1 , pp. 25-30
    • Vorona, R.D.1    Winn, M.P.2    Babineau, T.W.3    Eng, B.P.4    Feldman, H.R.5    Ware, J.C.6
  • 125
    • 33845665722 scopus 로고    scopus 로고
    • Obesity-related sleepiness and fatigue. The role of the stress system and cytokines
    • Vgontzas AN, Bixler EO, Chrousos GP. Obesity-related sleepiness and fatigue. The role of the stress system and cytokines. Ann NY Acad Sci 2006; 1083: 329-344.
    • (2006) Ann NY Acad Sci , vol.1083 , pp. 329-344
    • Vgontzas, A.N.1    Bixler, E.O.2    Chrousos, G.P.3
  • 128
    • 0027238259 scopus 로고
    • Augmented resting sympathetic activity in awake patients with obstructive sleep apnea
    • Carlson JT, Hedner J, Elam M, et al. Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest 103, 1763-1768: 1993. (Pubitemid 23174312)
    • (1993) Chest , vol.103 , Issue.6 , pp. 1763-1768
    • Carlson, J.T.1    Hedner, J.2    Elam, M.3    Ejnell, H.4    Sellgren, J.5    Wallin, B.G.6
  • 129
    • 33745828640 scopus 로고    scopus 로고
    • Insulin resistance and atherosclerosis
    • DOI 10.1172/JCI29024
    • Semenkovich CF. Insulin resistance and atherosclerosis. J Clin Invest 2006; 116: 1813-1822. (Pubitemid 44033301)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1813-1822
    • Semenkovich, C.F.1
  • 130
    • 42949088997 scopus 로고    scopus 로고
    • The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance
    • Goossens GH. The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance. Physiol Behav 2008; 94: 206-218.
    • (2008) Physiol Behav , vol.94 , pp. 206-218
    • Goossens, G.H.1
  • 131
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1


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