Obesity without sleep apnea is associated with daytime sleepiness

Archives of Internal Medicine

Volumn 158, Issue 12, 1998, Pages 1333-1337

  Vgontzas, Alexandras N ^a   Bixler, Edward O ^a   Tan, Tjiauw Ling ^a   Kantner, Deborah ^a   Martin, Louis F ^a   Kales, Anthony ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DROWSINESS; FATIGUE; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; SLEEP PATTERN; SLEEP TIME; SOMNOLENCE;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CIRCADIAN RHYTHM; FEMALE; HUMANS; MALE; MIDDLE AGED; OBESITY; SLEEP APNEA SYNDROMES; SLEEP STAGES;

EID: 0031860837     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.158.12.1333     Document Type: Article

References (17)

1. Kuczmarski RJ, Flegal DM, Campbell SM, Johnson CL. Increasing prevalence of overweight among US adults. JAMA. 1994;272:205-211.
2. Sjöström LV. Mortality of severely obese subjects. Am J Clin Nutr. 1992;55: 516S-523S.
3. Sjöström LV. Morbidity of severely obese subjects. Am J Clin Nutr. 1992;55: 508S-515S.
4. Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med. 1994;154:1705-1711.
5. Guilleminault C, Stoohs R, Clerk A, Cetel M, Maistros P. A cause of excessive daytime sleepiness: the upper airway resistance syndrome. Sleep, 1993;104: 781-787.
6. Kales A, Bixler EO, Soldates CR, Cadieux RJ, Manfredi RL, Vela-Bueno A. Narcolepsy/cataplexy, IV: diagnostic value of daytime nap recordings. Acta Neurol Scand. 1987;75:223-230.
7. Roth B, Nevšimalová S, Šonka K, Dočekal P. An alternative to the multiple sleep latency test for determining sleepiness in narcolepsy and hypersomnia: polygraphic score of sleepiness. Sleep. 1986;9:243-245.
8. Rechtschaffen A, Kales A. A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. Washington, DC: US Government Printing Office; 1968. NIH publication 204.
9. Bixler EO, Kales A, Soldatos CR. Prevalence of sleep disorders in the Los Angeles metropolitan area. Am J Psychiatry. 1979;11:1257-1262.
10. McCartt AT, Hammer MC. The scope and nature of the drowsy driving problem in New York state. Paper presented at: Annual Meeting of the Association for the Advancement of Automotive Medicine; October 18, 1995; Chicago, III.
11. US Congress Office of Technology Assessment. Gearing up for Safety: Motor Carrier Safer in a Competitive Environment. Washington, DC: Government Printing Office; 1988.
12. National Transportation Safety Board, Safety Study: Fatigue, Alcohol and Other Drugs, and Medical Factors in Fatal-to-the-Driver Heavy Truck Crashes. Vol 2. Washington, DC: Government Printing Office; 1990. Publication NTSB/SS-90/02.
13. Stoohs R, Bingham L, Itoi A, Guilleminault C, Dement WC. Sleep and sleep disordered breathing in commercial long-haul truck drivers. Chest. 1995;107:1275-1282.
14. Thorpy MJ. The clinical use of the Multiple Sleep Latency Test: the Standards of Practice Committee of the American Sleep Disorders Association. Sleep. 1992; 15:268-276.
15. Rand CSW, Macgregor AMC, Stunkard AJ. The night eating syndrome in the general population and among postoperative obesity surgery patients. Int J Eat Disord. 1997;22:65-69.
16. Vgontzas AN, Papanicolaou DA, Bixler EO, Kales A, Tyson K, Chrousos GP. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity. J Clin Endocrinol Metab. 1997;82:1313-1316.
17. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis iactor-α: direct role in obesity-linked insulin resistance. Science. 1993; 259:87-91.