-
1
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer
-
Almand B., Clark J.I., Nikitina E., van Beynen J., English N.R., Knight S.C., et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166 (2001) 678-689
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
van Beynen, J.4
English, N.R.5
Knight, S.C.6
-
2
-
-
0028965830
-
Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex
-
Aoe T., Okamoto Y., and Saito T. Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex. J Exp Med 181 (1995) 1881-1886
-
(1995)
J Exp Med
, vol.181
, pp. 1881-1886
-
-
Aoe, T.1
Okamoto, Y.2
Saito, T.3
-
3
-
-
0015596284
-
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent
-
Babior B.M., Kipnes R.S., and Curnutte J.T. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest 52 (1973) 741-744
-
(1973)
J Clin Invest
, vol.52
, pp. 741-744
-
-
Babior, B.M.1
Kipnes, R.S.2
Curnutte, J.T.3
-
5
-
-
33846626054
-
Regulation of T-cell activation by the cytoskeleton
-
Billadeau D.D., Nolz J.C., and Gomez T.S. Regulation of T-cell activation by the cytoskeleton. Nat Rev Immunol 7 (2007) 131-143
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 131-143
-
-
Billadeau, D.D.1
Nolz, J.C.2
Gomez, T.S.3
-
7
-
-
0034792157
-
Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation
-
Claiborne A., Mallet T., Yeh J., Luba J., and Parsonage G. Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation. Adv Prot Chem 58 (2000) 215-276
-
(2000)
Adv Prot Chem
, vol.58
, pp. 215-276
-
-
Claiborne, A.1
Mallet, T.2
Yeh, J.3
Luba, J.4
Parsonage, G.5
-
8
-
-
0035399959
-
How is actin polymerization nucleated in vivo?
-
Condeelis J. How is actin polymerization nucleated in vivo?. Trends Cell Biol 11 (2001) 288-293
-
(2001)
Trends Cell Biol
, vol.11
, pp. 288-293
-
-
Condeelis, J.1
-
9
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
Diaz-Montero C.M., Salem M.L., Nishimura M.I., Garrett-Mayer E., Cole D.J., and Montero A.J. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58 (2009) 49-59
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
10
-
-
35648969165
-
Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses
-
Dustin M.L. Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses. Curr Opin Cell Biol 19 (2007) 529-533
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 529-533
-
-
Dustin, M.L.1
-
11
-
-
1242341975
-
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation
-
Eibert S.M., Lee K.H., Pipkorn R., Sester U., Wabnitz G.H., Giese T., et al. Cofilin peptide homologs interfere with immunological synapse formation and T cell activation. Proc Natl Acad Sci USA 101 (2004) 1957-1962
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1957-1962
-
-
Eibert, S.M.1
Lee, K.H.2
Pipkorn, R.3
Sester, U.4
Wabnitz, G.H.5
Giese, T.6
-
12
-
-
0036710563
-
Cell signalling and the glutathione redox system
-
Filomeni G., Rotilio G., and Ciriolo M.R. Cell signalling and the glutathione redox system. Biochem Pharmacol 64 (2002) 1057-1064
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1057-1064
-
-
Filomeni, G.1
Rotilio, G.2
Ciriolo, M.R.3
-
13
-
-
0027378767
-
Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma
-
Finke J.H., Zea A.H., Stanley J., Longo D.L., Mizoguchi H., Tubbs R.R., et al. Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma. Cancer Res 53 (1993) 5613-5616
-
(1993)
Cancer Res
, vol.53
, pp. 5613-5616
-
-
Finke, J.H.1
Zea, A.H.2
Stanley, J.3
Longo, D.L.4
Mizoguchi, H.5
Tubbs, R.R.6
-
14
-
-
0028150839
-
Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction
-
Flescher E., Ledbetter J.A., Schieven G.L., Vela-Roch N., Fossum D., Dang H., et al. Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction. J Immunol 153 (1994) 4880-4889
-
(1994)
J Immunol
, vol.153
, pp. 4880-4889
-
-
Flescher, E.1
Ledbetter, J.A.2
Schieven, G.L.3
Vela-Roch, N.4
Fossum, D.5
Dang, H.6
-
15
-
-
0031573790
-
Mouse LIM-kinase 2 gene: cDNA cloning, genomic organization, and tissue-specific expression of two alternatively initiated transcripts
-
Ikebe C., Ohashi K., Fujimori T., Bernard O., Noda T., Robertson E.J., et al. Mouse LIM-kinase 2 gene: cDNA cloning, genomic organization, and tissue-specific expression of two alternatively initiated transcripts. Genomics 46 (1997) 504-508
-
(1997)
Genomics
, vol.46
, pp. 504-508
-
-
Ikebe, C.1
Ohashi, K.2
Fujimori, T.3
Bernard, O.4
Noda, T.5
Robertson, E.J.6
-
16
-
-
4444221709
-
T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
-
Jackson S.H., Devadas S., Kwon J., Pinto L.A., and Williams M.S. T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation. Nat Immunol 5 (2004) 818-827
-
(2004)
Nat Immunol
, vol.5
, pp. 818-827
-
-
Jackson, S.H.1
Devadas, S.2
Kwon, J.3
Pinto, L.A.4
Williams, M.S.5
-
17
-
-
0033869092
-
Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress
-
Klatt P., and Lamas S. Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 267 (2000) 4928-4944
-
(2000)
Eur J Biochem
, vol.267
, pp. 4928-4944
-
-
Klatt, P.1
Lamas, S.2
-
18
-
-
51349166966
-
Oxidation of cofilin mediates T cell hyporesponsiveness under oxidative stress conditions
-
Klemke M, Wabnitz GH, Funke F, Funk B, Kirchgessner H, Samstag Y. Oxidation of cofilin mediates T cell hyporesponsiveness under oxidative stress conditions. Immunity 2008;29:404-13.
-
(2008)
Immunity
, vol.29
, pp. 404-413
-
-
Klemke, M.1
Wabnitz, G.H.2
Funke, F.3
Funk, B.4
Kirchgessner, H.5
Samstag, Y.6
-
19
-
-
0029828089
-
Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer
-
Kono K., Ressing M.E., Brandt R.M., Melief C.J., Potkul R.K., Andersson B., et al. Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer. Clin Cancer Res 2 (1996) 1825-1828
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1825-1828
-
-
Kono, K.1
Ressing, M.E.2
Brandt, R.M.3
Melief, C.J.4
Potkul, R.K.5
Andersson, B.6
-
20
-
-
0030048536
-
Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity
-
Kono K., Salazar-Onfray F., Petersson M., Hansson J., Masucci G., Wasserman K., et al. Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity. Eur J Immunol 26 (1996) 1308-1313
-
(1996)
Eur J Immunol
, vol.26
, pp. 1308-1313
-
-
Kono, K.1
Salazar-Onfray, F.2
Petersson, M.3
Hansson, J.4
Masucci, G.5
Wasserman, K.6
-
21
-
-
25444456369
-
+ T cell tolerance induced by bone marrow-derived immature myeloid cells
-
+ T cell tolerance induced by bone marrow-derived immature myeloid cells. J Immunol 175 (2005) 4583-4592
-
(2005)
J Immunol
, vol.175
, pp. 4583-4592
-
-
Kusmartsev, S.1
Nagaraj, S.2
Gabrilovich, D.I.3
-
22
-
-
0031936187
-
Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes
-
Lahdenpohja N., Savinainen K., and Hurme M. Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes. J Immunol 160 (1998) 1354-1358
-
(1998)
J Immunol
, vol.160
, pp. 1354-1358
-
-
Lahdenpohja, N.1
Savinainen, K.2
Hurme, M.3
-
23
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth J.D. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 4 (2004) 181-189
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
24
-
-
0034004460
-
Cofilin: a missing link between T cell co-stimulation and rearrangement of the actin cytoskeleton
-
Lee K.H., Meuer S.C., and Samstag Y. Cofilin: a missing link between T cell co-stimulation and rearrangement of the actin cytoskeleton. Eur J Immunol 30 (2000) 892-899
-
(2000)
Eur J Immunol
, vol.30
, pp. 892-899
-
-
Lee, K.H.1
Meuer, S.C.2
Samstag, Y.3
-
25
-
-
0035451662
-
Inhibition of activated/memory (CD45RO(+)) T cells by oxidative stress associated with block of NF-kappaB activation
-
Malmberg K.J., Arulampalam V., Ichihara F., Petersson M., Seki K., Andersson T., et al. Inhibition of activated/memory (CD45RO(+)) T cells by oxidative stress associated with block of NF-kappaB activation. J Immunol 167 (2001) 2595-2601
-
(2001)
J Immunol
, vol.167
, pp. 2595-2601
-
-
Malmberg, K.J.1
Arulampalam, V.2
Ichihara, F.3
Petersson, M.4
Seki, K.5
Andersson, T.6
-
26
-
-
0029042847
-
Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease
-
Matsuda M., Petersson M., Lenkei R., Taupin J.L., Magnusson I., Mellstedt H., et al. Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. Int J Cancer 61 (1995) 765-772
-
(1995)
Int J Cancer
, vol.61
, pp. 765-772
-
-
Matsuda, M.1
Petersson, M.2
Lenkei, R.3
Taupin, J.L.4
Magnusson, I.5
Mellstedt, H.6
-
27
-
-
0028335706
-
Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif
-
Mizuno K., Okano I., Ohashi K., Nunoue K., Kuma K., Miyata T., et al. Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. Oncogene 9 (1994) 1605-1612
-
(1994)
Oncogene
, vol.9
, pp. 1605-1612
-
-
Mizuno, K.1
Okano, I.2
Ohashi, K.3
Nunoue, K.4
Kuma, K.5
Miyata, T.6
-
28
-
-
0029678546
-
Phosphorylation of Ser-3 of cofilin regulates its essential function on actin
-
Moriyama K., Iida K., and Yahara I. Phosphorylation of Ser-3 of cofilin regulates its essential function on actin. Genes Cells 1 (1996) 73-86
-
(1996)
Genes Cells
, vol.1
, pp. 73-86
-
-
Moriyama, K.1
Iida, K.2
Yahara, I.3
-
31
-
-
0027453988
-
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma
-
Nakagomi H., Petersson M., Magnusson I., Juhlin C., Matsuda M., Mellstedt H., et al. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res 53 (1993) 5610-5612
-
(1993)
Cancer Res
, vol.53
, pp. 5610-5612
-
-
Nakagomi, H.1
Petersson, M.2
Magnusson, I.3
Juhlin, C.4
Matsuda, M.5
Mellstedt, H.6
-
32
-
-
0242656355
-
Dephosphorylation of cofilin is regulated through Ras and requires the combined activities of the Ras-effectors MEK and PI3K
-
Nebl G., Fischer S., Penzel R., and Samstag Y. Dephosphorylation of cofilin is regulated through Ras and requires the combined activities of the Ras-effectors MEK and PI3K. Cell Signal 16 (2004) 235-243
-
(2004)
Cell Signal
, vol.16
, pp. 235-243
-
-
Nebl, G.1
Fischer, S.2
Penzel, R.3
Samstag, Y.4
-
33
-
-
0029841427
-
Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses
-
Otsuji M., Kimura Y., Aoe T., Okamoto Y., and Saito T. Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci USA 93 (1996) 13119-13124
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13119-13124
-
-
Otsuji, M.1
Kimura, Y.2
Aoe, T.3
Okamoto, Y.4
Saito, T.5
-
34
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll D. Does the immune system see tumors as foreign or self?. Annu Rev Immunol 21 (2003) 807-839
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
35
-
-
0036911138
-
Hydrogen peroxide as second messenger in lymphocyte activation
-
Reth M. Hydrogen peroxide as second messenger in lymphocyte activation. Nat Immunol 3 (2002) 1129-1134
-
(2002)
Nat Immunol
, vol.3
, pp. 1129-1134
-
-
Reth, M.1
-
36
-
-
8644227615
-
Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy
-
Robinson J.M., Ohira T., and Badwey J.A. Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy. Histochem Cell Biol 122 (2004) 293-304
-
(2004)
Histochem Cell Biol
, vol.122
, pp. 293-304
-
-
Robinson, J.M.1
Ohira, T.2
Badwey, J.A.3
-
37
-
-
0025823771
-
A serine phosphatase is involved in CD2-mediated activation of human T lymphocytes and natural killer cells
-
Samstag Y., Bader A., and Meuer S.C. A serine phosphatase is involved in CD2-mediated activation of human T lymphocytes and natural killer cells. J Immunol 147 (1991) 788-794
-
(1991)
J Immunol
, vol.147
, pp. 788-794
-
-
Samstag, Y.1
Bader, A.2
Meuer, S.C.3
-
38
-
-
0026499536
-
Dephosphorylation of pp19: a common second signal for human T cell activation mediated through different accessory molecules
-
Samstag Y., Henning S.W., Bader A., and Meuer S.C. Dephosphorylation of pp19: a common second signal for human T cell activation mediated through different accessory molecules. Int Immunol 4 (1992) 1255-1262
-
(1992)
Int Immunol
, vol.4
, pp. 1255-1262
-
-
Samstag, Y.1
Henning, S.W.2
Bader, A.3
Meuer, S.C.4
-
39
-
-
0028279844
-
Costimulatory signals for human T-cell activation induce nuclear translocation of pp19/cofilin
-
Samstag Y., Eckerskorn C., Wesselborg S., Henning S., Wallich R., and Meuer S.C. Costimulatory signals for human T-cell activation induce nuclear translocation of pp19/cofilin. Proc Natl Acad Sci USA 91 (1994) 4494-4498
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4494-4498
-
-
Samstag, Y.1
Eckerskorn, C.2
Wesselborg, S.3
Henning, S.4
Wallich, R.5
Meuer, S.C.6
-
40
-
-
0037244777
-
Actin cytoskeletal dynamics in T lymphocyte activation and migration
-
Samstag Y., Eibert S.M., Klemke M., and Wabnitz G.H. Actin cytoskeletal dynamics in T lymphocyte activation and migration. J Leukoc Biol 73 (2003) 30-48
-
(2003)
J Leukoc Biol
, vol.73
, pp. 30-48
-
-
Samstag, Y.1
Eibert, S.M.2
Klemke, M.3
Wabnitz, G.H.4
-
41
-
-
0035874990
-
Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
-
Schmielau J., and Finn O.J. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res 61 (2001) 4756-4760
-
(2001)
Cancer Res
, vol.61
, pp. 4756-4760
-
-
Schmielau, J.1
Finn, O.J.2
-
42
-
-
0035294392
-
Suppressed T-cell receptor zeta chain expression and cytokine production in pancreatic cancer patients
-
Schmielau J., Nalesnik M.A., and Finn O.J. Suppressed T-cell receptor zeta chain expression and cytokine production in pancreatic cancer patients. Clin Cancer Res 7 (2001) 933s-939s
-
(2001)
Clin Cancer Res
, vol.7
-
-
Schmielau, J.1
Nalesnik, M.A.2
Finn, O.J.3
-
43
-
-
31344474166
-
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression
-
Serafini P., Borrello I., and Bronte V. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol 16 (2006) 53-65
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 53-65
-
-
Serafini, P.1
Borrello, I.2
Bronte, V.3
-
44
-
-
27544443327
-
Molecular composition and regulation of the Nox family NAD(P)H oxidases
-
Sumimoto H., Miyano K., and Takeya R. Molecular composition and regulation of the Nox family NAD(P)H oxidases. Biochem Biophys Res Commun 338 (2005) 677-686
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 677-686
-
-
Sumimoto, H.1
Miyano, K.2
Takeya, R.3
-
45
-
-
34548770748
-
The CD16-/CD56bright subset of NK cells is resistant to oxidant-induced cell death
-
Thoren F.B., Romero A.I., Hermodsson S., and Hellstrand K. The CD16-/CD56bright subset of NK cells is resistant to oxidant-induced cell death. J Immunol 179 (2007) 781-785
-
(2007)
J Immunol
, vol.179
, pp. 781-785
-
-
Thoren, F.B.1
Romero, A.I.2
Hermodsson, S.3
Hellstrand, K.4
-
46
-
-
31144470414
-
Phosphatidylinositol 3-kinase functions as a Ras effector in the signaling cascade that regulates dephosphorylation of the actin-remodeling protein cofilin after costimulation of untransformed human T lymphocytes
-
Wabnitz G.H., Nebl G., Klemke M., Schroder A.J., and Samstag Y. Phosphatidylinositol 3-kinase functions as a Ras effector in the signaling cascade that regulates dephosphorylation of the actin-remodeling protein cofilin after costimulation of untransformed human T lymphocytes. J Immunol 176 (2006) 1668-1674
-
(2006)
J Immunol
, vol.176
, pp. 1668-1674
-
-
Wabnitz, G.H.1
Nebl, G.2
Klemke, M.3
Schroder, A.J.4
Samstag, Y.5
|