Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreaticβ-cell function

Endocrinology

Volumn 150, Issue 5, 2009, Pages 2072-2079

  Hammar, Eva ^a   Tomas, Alejandra ^a   Bosco, Domenico ^b   Halban, Philippe A ^a,c  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY HOSPITAL   (Switzerland)

^c University Medical Center   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; CYCLIN DEPENDENT KINASE 1; EXOENZYME C3; GLUCOSE; INSULIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 METHYL 1 ((4 METHYL 5 ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; AMIDE; DRUG DERIVATIVE; ENZYME INHIBITOR; PYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL SPREADING; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MICROFILAMENT; PHYSIOLOGY; SECRETION; TIME; WISTAR RAT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMIDES; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MALE; MICROFILAMENTS; PYRIDINES; RATS; RATS, WISTAR; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 66449096364     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1135     Document Type: Article

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