Marked increase of insulin gene transcription by suppression of the Rho/Rho-kinase pathway

Biochemical and Biophysical Research Communications

Volumn 350, Issue 1, 2006, Pages 68-73

  Nakamura, Yumiko ^a   Kaneto, Hideaki ^a   Miyatsuka, Takeshi ^a   Matsuoka, Taka aki ^a   Matsuhisa, Munehide ^a   Node, Koichi ^b   Hori, Masatsugu ^a   Yamasaki, Yoshimitsu ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SAGA UNIVERSITY   (Japan)

Author keywords

Diabetes; Insulin; Rho kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; FASUDIL; LUCIFERASE; RHO FACTOR; RHO KINASE; RHO KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME INHIBITION; GENE INACTIVATION; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SYNTHESIS; MESSENGER RNA SYNTHESIS; MOUSE; NONHUMAN; NORTHERN BLOTTING; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE;

ANIMALS; CELL LINE; DIABETES MELLITUS; DNA; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; PANCREAS; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 33749071005     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.192     Document Type: Article

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